Genentech: Publications

February 13, 1998

A novel soluble tissue factor variant with an altered factor VIIa binding interface

Journal of Biological Chemistry, ISSN: 00219258

Geoffrey F. Lee; Robert F. Kelley

February 6, 1998

Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability

Journal of Biological Chemistry, ISSN: 00219258

Terri Davis-Smyth; Presta; Napoleone Ferrara

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February 5, 1998

Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain

Nature Structural Biology, ISSN: 10728368

Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III

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February 5, 1998

Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase

Nature Structural Biology, ISSN: 10728368

Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother

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February 3, 1998

Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis

Circulation, ISSN: 00097322

Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner

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February 3, 1998

Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial

Circulation, ISSN: 00097322

Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald

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February 3, 1998

Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial

Circulation, ISSN: 00097322

Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald

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February 1, 1998

Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)

Journal of Neuroscience, ISSN: 02706474

Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière

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February 1, 1998

Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages

European Journal of Neuroscience, ISSN: 0953816X

Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies

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February 1, 1998

An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2

Cancer Research, ISSN: 00085472

Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny

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February 1, 1998

Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis

Pediatric Pulmonology, ISSN: 87556863

David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan

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February 1, 1998

Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate

Journal of Cellular Biochemistry, ISSN: 07302312

Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth

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January 30, 1998

An induced proximity model for caspase-8 activation

Journal of Biological Chemistry, ISSN: 00219258

Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit

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January 26, 1998

Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis

Journal of Molecular Structure: THEOCHEM, ISSN: 01661280

Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent

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January 22, 1998

Calcium-dependent Ret activation by GDNF and neurturin

Oncogene, ISSN: 09509232

Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi

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January 15, 1998

Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis

Journal of Immunology, ISSN: 00221767

Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore

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January 9, 1998

Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein

Journal of Biological Chemistry, ISSN: 00219258

Dowbenko; Spencer; Quan; Lasky

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January 9, 1998

Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide

Journal of Biological Chemistry, ISSN: 00219258

Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis

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January 2, 1998

Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice

Journal of Biological Chemistry, ISSN: 00219258

Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff

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January 1, 1998

Disturbances of growth hormone-insulin-like growth factor axis and response to growth hormone in acidosis

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119

Karina Jandziszak; Carlos Suarez; Ethan Wasserman; Ross Clark; Bonnie Baker; Frances Liu; Hintz; Saenger; Luc P. Brion

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January 1, 1998

Expression analysis of the soluble and membrane-associated forms of the interleukin-1 receptor-related T1 protein in primary mast cells and fibroblasts

Hybridoma, ISSN: 0272457X

Dirk R. Moritz; Jacqueline Gheyselinck; Roman Klemenz

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January 1, 1998

A method of biased coin randomization, its implementation, and its validation

Drug Information Journal, ISSN: 00928615

James W. Frane

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January 1, 1998

X-linked chronic granulomatous disease: Mutations in the CYBB gene encoding the gp91-phox component of respiratory-burst oxidase

American Journal of Human Genetics, ISSN: 00029297

Julie Rae; Peter E. Newburger; Mary C. Dinauer; Noack; Penelope J. Hopkins; Ryoko Kuruto; John T. Curnutte

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January 1, 1998

P-glycoprotein (P-gp) mediated efflux in Caco-2 cell monolayers: The influence of culturing conditions and drug exposure on P-gp expression levels

Journal of Pharmaceutical Sciences, ISSN: 00223549

Pascale Anderle; Eva Niederer; Rubas; Constanze Hilgendorf; Hilde Spahn-Langguth; Heidi Wunderli-Allenspach; Hans P. Merkle; Peter Langguth

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January 1, 1998

Regulation of megakaryocytopoiesis and platelet production: Lessons from animal models

Journal of Laboratory and Clinical Medicine, ISSN: 00222143

Frederic J. De Sauvage; Jean-Luc Villeval; Ramesh A. Shivdasani

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January 1, 1998

Acetogenesis does not replace ketogenesis in fasting piglets infused with hexanoate

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Adams; Jack Odle

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January 1, 1998

Treatment of idiopathic bronchiectasis with aerosolized recombinant human DNase I

Chest, ISSN: 00123692

Anne E. O'Donnell; Alan F. Barker; Jonathan S. Ilowite; Robert B. Fick Jr.

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January 1, 1998

Magnetic resonance imaging detects suppression of tumor vascular permeability after administration of antibody to vascular endothelial growth factor

Cancer Investigation, ISSN: 07357907

Christine D. Pham; Timothy P.L. Roberts; Nicholas Van Bruggen; Ostap Melnyk; Jeffry Mann; Napoleone Ferrara; Robert L. Cohen; Robert C. Brasch

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January 1, 1998

E. coli-based in vitro transcription/translation: In vivo-specific synthesis rates and high yields in a batch system

BioTechniques, ISSN: 07366205

Ranjan Patnaik; James R. Swartz

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January 1, 1998

Effect of excipients on the stability and structure of lyophilized recombinant human growth hormone

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Karen G. Carrasquillo; Rocio A. Cordero; Mumenthaler; Chung C. Hsu; Kai Griebenow

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January 1, 1998

Mutational analysis of human DNase I at the DNA binding interface: Implications for DNA recognition, catalysis, and metal ion dependence

Protein Science, ISSN: 09618368

Clark Q. Pan; Jana S. Ulmer; Herzka; Lazarus

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January 1, 1998

Recent antibody targeting technologies - A survey of the patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

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January 1, 1998

For success, focus your strengths.

Nature Biotechnology, ISSN: 10870156

Levinson

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January 1, 1998

Hinge bending within the cytokine receptor superfamily revealed by the 2.4 Å crystal structure of the extracellular domain of rabbit tissue factor

Protein Science, ISSN: 09618368

Yves A. Muller; Robert F. Kelley; De Vos

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January 1, 1998

Phage display of peptide libraries on protein scaffolds.

Methods in Molecular Biology, ISSN: 10643745

Henry B. Lowman

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January 1, 1998

New branches on the neuregulin family tree

Molecular Psychiatry, ISSN: 13594184

Godowski; Zhang; Gretchen D. Frantz

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January 1, 1998

Rapid identification of comigrating gel-isolated proteins by ion trap- mass spectrometry

Electrophoresis, ISSN: 01730835

David Arnott; William J. Henzel; Stults

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January 1, 1998

Crystallization and preliminary X-ray analysis of a 1:1 complex between a designed monomeric interferon-gamma and its soluble receptor

Protein Science, ISSN: 09618368

Michael Randal; Anthony A. Kossiakoff

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January 1, 1998

Short communication: Renal tubular vacuolation in animals treated with polyethylene-glycol-conjugated proteins

Toxicological Sciences, ISSN: 10966080

Alison Bendele; Jim Seely; Carl Richey; Gina Sennello; Shopp

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January 1, 1998

Cardiotrophin-1 induces heat shock protein accumulation in cultured cardiac cells and protects them from stressful stimuli

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Anastatis Stephanou; Bhawanjit K. Brar; Heads; Knight; Marber; Diane Pennica; David S. Latchman

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January 1, 1998

Maintenance of myonuclear domain size in rat soleus after overload and growth hormone/IGF-I treatment

Journal of Applied Physiology, ISSN: 87507587

McCall; Allen; Jon K. Linderman; Richard E. Grindeland; Roy; Mukku; Edgerton

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January 1, 1998

Humanization of an antibody against human protein C and calcium-dependence involving framework residues

Protein Engineering, ISSN: 02692139

Shane J. O'Connor; Meng; Alireza R. Rezaie; Presta

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January 1, 1998

Inorganic polyphosphate in Escherichia coli: The phosphate regulon and the stringent response

Journal of Bacteriology, ISSN: 00219193

Narayana N. Rao; Shengjiang Liu; Arthur Kornberg

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January 1, 1998

Inhibin gene expression in a large cell calcifying Sertoli cell tumour and serum inhibin and activin levels

APMIS, ISSN: 09034641

Jorma Toppari; Antti Kaipia; Marko Kaleva; Matti Laato; David M. De Kretser; Lynne Krummen; Mather; Toivo T. Salmi

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January 1, 1998

Comparison of VEGF delivery techniques on collateral-dependent microvascular reactivity

Microvascular Research, ISSN: 00262862

Frank W Sellke; Motohisa Tofukuji; Roger J Laham; Jianyi Li; Mukesh D. Hariawala; Bunting; Michael Simons

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January 1, 1998

A cell-based potency assay for insulin-like growth factor-I

Biologicals, ISSN: 10451056

Hélène Gazzano-Santoro; Chen; Mukku

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January 1, 1998

Hematopoietic deficiencies in c-mpl and TPO knockout mice

Stem Cells, ISSN: 10665099

Maximilien Murone; David Carpenter; Frederic J. De Sauvage

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January 1, 1998

Endogenous serum thrombopoietin concentrations in patients with myelodysplastic syndromes

Leukemia, ISSN: 08876924

Heinz Zwierzina; Rollinger-Holzinger; Nuessler; Herold; Meng

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January 1, 1998

Persephin, a novel neurotrophic factor related to GDNF and neurturin

Neuron, ISSN: 08966273

Jeffrey Milbrandt; Frederic J. De Sauvage; Timothy J. Fahrner; Robert H. Baloh; Melanie L. Leitner; Malú G. Tansey; Patricia A. Lampe; Robert O. Heuckeroth; Paul T. Kotzbauer; Kelli S. Simburger; Judith P. Golden; Jamie A. Davies; Richard Vejsada; Ann C. Kato; Mary Hynes; Sherman; Merry Nishimura; Li-Chong Wang; Richard L. Vandlen; Moffat; Robert D. Klein; Kris Poulsen; Christa Gray; Alain Garces; Christopher E. Henderson; Phillips; Eugene M. Johnson Jr.

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January 1, 1998

Spray-drying of air-liquid interface sensitive recombinant human growth hormone

Journal of Pharmaceutical Sciences, ISSN: 00223549

Maa; Phuong-Anh Nguyen; Selena W. Hsu

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