Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 16681 RESULTS

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin
Journal of Cell Biology, ISSN: 00219525
Danxi Li; Mrsny
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Comparison of three treatment options for single brain metastasis from lung cancer
International Journal of Cancer, ISSN: 00207136
Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc
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High copy display of large proteins on phage for functional selections
Journal of Molecular Biology, ISSN: 00222836
Sachdev S. Sidhu; Gregory A. Weiss; James A. Wells
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Convergent solutions to binding at a protein-protein interface
Science, ISSN: 00368075
Warren L. DeLano; Ultsch; De Vos; James A. Wells
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Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor- related apoptosis-inducing ligand in vitro and in vivo
Cancer Research, ISSN: 00085472
Motoo Nagane; Pan; Jessie J. Weddle; Vishva M. Dixit; Cavenee; Su Huang
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Assessment of the myotoxicity of pharmaceutical buffers using an in vitro muscle model: Effect of pH, capacity, tonicity, and buffer type
Pharmaceutical Development and Technology, ISSN: 10837450
Jintana Napaporn; Maike Thomas; Kari A. Svetic; Shahrokh; Gayle A. Brazeau
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Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling
Journal of Experimental Medicine, ISSN: 00221007
Tomasz Sosinowski; Akhilesh Pandey; Vishva M. Dixit; Arthur Weiss
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Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3- containing proapoptosis protein in the cytoplasm
Journal of Biological Chemistry, ISSN: 00219258
Shih-Chong Tsai; Kishore B. S. Pasumarthi; Laura Pajak; Michael Franklin; Brian Patton; He Wang; William J. Henzel; Stults; Loren J. Field
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Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator
American Journal of Cardiology, ISSN: 00029149
Hal V. Barron; Amy Chen Rundle; Joel M. Gore; Jerry H. Gurwitz; Jan Penney
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High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update
Cancer Journal from Scientific American, ISSN: 10814442
Michael B. Atkins; Lori Kunkel; Mario Sznol; Steven A. Rosenberg
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Isolation and characterization of CRF-related diuretic hormones from the whitelined sphinx moth Hyles lineata
Insect Biochemistry and Molecular Biology, ISSN: 09651748
Kenji Furuya; Marilyn A. Harper; Kathleen M. Schegg; David A. Schooley
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Transient focal cerebral ischemia induces sensorimotor deficits in mice
Behavioural Brain Research, ISSN: 01664328
Gerlai; Harold Thibodeaux; James T. Palmer; Menno Van Lookeren Campagne; Nicholas Van Bruggen
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Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma
Cancer Journal from Scientific American, ISSN: 10814442
Richard I. Fisher; Steven A. Rosenberg; Gwendolyn Fyfe
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Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway
Journal of Neurochemistry, ISSN: 00223042
Hugh J. L. Fryer; Daniel H. Wolf; Ronald J. Knox; Stephen M. Strittmatter; Diane Pennica; O'Leary; David S. Russell; Robert G. Kalb
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Green fluorescent protein as a second selectable marker for selection of high producing clones from transfected CHO cells
Gene, ISSN: 03781119
Meng; Jie Liang; Wai Lee T. Wong; Chisholm
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Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons
Journal of Cell Biology, ISSN: 00219525
Gayle Middleton; Makoto Hamanoue; Yasushi Enokido; Sean Wyatt; Diane Pennica; Ellis Jaffray; Ronald T. Hay; Alun M. Davies
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Coarse spray delivery to a localized region of the pulmonary airways for gene therapy
Human Gene Therapy, ISSN: 10430342
Cipolla; Gonda; Steven Shak; Kovesdi; Crystal; Sweeney
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Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hanzhong Li; Jian Chen; Arthur Huang; Stinson; Sherry Heldens; Foster; Patrick Dowd; Austin L. Gurney; William I. Wood
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RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Peyman; Volkmar Wehner; Knolle; Stilz; Breipohl; Karl-Heinz Scheunemann; Denis Carniato; Ruxer; Gourvest; Thomas Gadek; Bodary
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Kistrin inhibits human smooth muscle cell interaction with fibrin
Thrombosis Research, ISSN: 00493848
Karen O Yee; Yuji Ikari; Bodary; Schwartz
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A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain
Journal of Neuroscience, ISSN: 02706474
Ted Zerucha; Thorsten Stühmer; Gary Hatch; Byung K. Park; Qiaoming Long; Guoying Yu; Adrianna Gambarotta; Joshua R. Schultz; John L. R. Rubenstein; Marc Ekker
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Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment
Biochemistry, ISSN: 00062960
David Meininger; Mark Rance; Melissa A. Starovasnik; Wayne J. Fairbrother; Nicholas J. Skelton
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Endothelial dysfunction, hemodynamic forces, and atherogenesis
Annals of the New York Academy of Sciences, ISSN: 00778923
Gimbrone Jr.; James N. Topper; Tobi Nagel; Keith R. Anderson; Guillermo Garcia-Cardeña
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Mobilization of vitamin A stores in rats after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin: A kinetic analysis
Toxicological Sciences, ISSN: 10966080
Sean K. Kelley; Charlotte B. Nilsson; Michael H. Green; Joanne Balmer Green; Helen Håkansson
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Measurement of the acid-labile subunit of the insulin-like growth factor binding protein complex in human serum: A comparison of four immunoassays
Journal of Endocrinology, ISSN: 00220795
Baxter; Svejkar; Khosravi; Bennett; Hardman; Senese; Mistry; Walton; Quarmby
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Can retinoic acid ameliorate the physiologic and morphologic effects of elastase instillation in the rat?
Chest, ISSN: 00123692
Tepper; Juergen Pfeifer; Melinda C. Aldrich; Daniel B. Tumas; Jeffrey Kern; Eric Hoffman; Geoffrey McLennan; Dallas M. Hyde
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Stimulation of osteoclast differentiation in vitro by mouse oncostatin M, leukaemia inhibitory factor, cardiotrophin-1 and interleukin 6: Synergy with dexamethasone
Cytokine, ISSN: 10434666
Richards; Langdon; Paula Deschamps; Diane Pennica; Stephen G. Shaughnessy
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Thrombopoietin in the thrombocytopenic term and preterm newborn
Pediatrics, ISSN: 00314005
Timothy S. E. Albert; Meng; Paul Simms; Robert L. Cohen; Roderic H. Phibbs
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Mutational analysis of the major coat protein of M13 identifies residues that control protein display
Protein Science, ISSN: 09618368
Gregory A. Weiss; James A. Wells; Sachdev S. Sidhu
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Species-specific variation in glycosylation of Igc: Evidence for the species-specific sialylation and branch-specific galactosylation and importance for engineering recombinant glycoprotein therapeutics
Glycobiology, ISSN: 09596658
T. Shantha Raju; Briggs; Steve M. Borge; Andrew J.S. Jones
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Integrin αIIbβ3 and ανβ3 inhibition reduces neointima after porcine coronary angioplasty
Heart, ISSN: 13556037
Chico; Gunn; Arnold; Sherron L. Bullens; Michael T. Lipari; Bunting; Cumberland; Crossman
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Uncoupling protein homologs: Emerging views of physiological function
Journal of Nutrition, ISSN: 00223166
Adams
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Alteplase as an alternative to urokinase
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Charles P. Semba; Curtis W. Bakal; Karim A. Calis; Gerald E. Grubbs; David W. Hunter; Terence A. S. Matalon; Timothy P. Murphy; David Stump; Steven Thomas; David L. Warner
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The rtPA (Alteplase) 0- to 6-hour acute stroke trial, part A (A0276g): Results of a double-blind, placebo-controlled, multicenter study
Stroke, ISSN: 00392499
Wayne M. Clark; Gregory W. Albers; Kenneth Madden; Scott Hamilton
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Use of rhDNase therapy and costs of respiratory-related care in patients with cystic fibrosis
Annals of Pharmacotherapy, ISSN: 10600280
Daniel A. Ollendorf; Lisa J. McGarry; Marc Watrous; Gerry Oster
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Recombination events between the p47-phox gene and its highly homologous pseudogenes are the main cause of autosomal recessive chronic granulomatous disease
Blood, ISSN: 00064971
Joachim Roesler; John T. Curnutte; Julie Rae; David Barrett; Pablo Patino; Stephen J. Chanock; Agnes Goerlach
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Genomic structure of the human p47-phox (NCF1) gene
Blood Cells, Molecules, and Diseases, ISSN: 10799796
Stephen J. Chanock; Joachim Roesler; Shixing Zhan; Penelope J. Hopkins; Pauline L. Lee; David Barrett; Barbara Christensen; John T. Curnutte; Agnes Görlach
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Body mass index (BMI) in Turner syndrome before and during growth hormone (GH) therapy
International Journal of Obesity, ISSN: 03070565
Blackett; Amy Chen Rundle; James W. Frane; Sandra L. Blethen
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Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis
Journal of the American Academy of Dermatology, ISSN: 01909622
Alice Gottlieb; James G. Krueger; Ross Bright; Mark Ling; Mark Lebwohl; Sewon Kang; Steve Feldman; Mary Spellman; Knut Wittkowski; Hans D. Ochs; Paula Jardieu; Bauer; Mark White; Russell L Dedrick; Marvin Garovoy
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Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1β
Molecular Human Reproduction, ISSN: 13609947
Dan I. Lebovic; Frauke Bentzien; Victor A. Chao; Evelyn N. Garrett; Meng; Robert N. Taylor
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Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium
Journal of Pharmaceutical Sciences, ISSN: 00223549
M. Christiane Schmidt; Daniel Simmen; Monika Hilbe; Peter Boderke; Günter Ditzinger; Jürgen Sandow; Steffen Lang; Rubas; Hans P. Merkle
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Fast probabilistic analysis of sequence function using scoring matrices
Bioinformatics, ISSN: 13674803
Thomas D Wu; Craig G. Nevill-Manning; Douglas L. Brutlag
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Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN
Experimental Neurology, ISSN: 00144886
Michael R. Hoane; Kamal D. Puri; Lei Xu; Paul F. Stabila; Hongmei Zhao; Amit G. Gulwadi; Phillips; Devaux; Mark D. Lindner; Weng Tao
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Estimation in a Cox proportional hazards cure model
Biometrics, ISSN: 0006341X
Sy; Jeremy M.G. Taylor
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Identification and regulation of receptor tyrosine kinases Rse and Mer and their ligand Gas6 in testicular somatic cells
Journal of Andrology, ISSN: 01963635
Michael C. W. Chan; Mather; Glynis McCray; Will M. Lee
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Use of phage display for the generation of human antibodies that neutralize factor IXa function
Blood Coagulation and Fibrinolysis, ISSN: 09575235
Shelley Suggett; Daniel Kirchhofer; Hass; Michael T. Lipari; Paul Moran; Nagel; Judice; Kurt A. Schroeder; Jeffrey Tom; Henry B. Lowman; Adams; Dan L. Eaton; Devaux
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Substrate-assisted catalysis: Molecular basis and biological significance
Protein Science, ISSN: 09618368
William Dall'Acqua; Paul J. Carter
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Web Alert. Apoptosis.
Chemistry and Biology, ISSN: 10745521
Eric W. Humke
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WECHE: A novel hematopoietic regulatory factor
Immunity, ISSN: 10747613
Osamu Ohneda; Kinuko Ohneda; Hisayuki Nomiyama; Zhong Zheng; Steven A. Gold; Fumio Arai; Takeshi Miyamoto; Bruce E. Taillon; Richard A. McIndoe; Richard A. Shimkets; Lewin; Toshio Suda; Lasky
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Targeting genes and proteins in the analysis of learning and memory: Caveats and future directions
Reviews in the Neurosciences, ISSN: 03341763
Gerlai
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