Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13051 - 13100 OF 16681 RESULTS

January 1, 2000

Magnetic resonance imaging in an experimental model of human ovarian cancer demonstrating altered microvascular permeability after inhibition of vascular endothelial growth factor

American Journal of Obstetrics and Gynecology, ISSN: 00029378

Axel Gossmann; Thomas H. Helbich; Sam Mesiano; David M. Shames; Michael F. Wendland; Timothy P.L. Roberts; Napoleone Ferrara; Robert B. Jaffe; Robert C. Brasch

January 1, 2000

Translation and linguistic validation of a disease-specific quality of life measure for cystic fibrosis

Journal of Pediatric Psychology, ISSN: 01468693

Alexandra L. Quittner; Sheri Sweeny; Marc Watrous; Paul Munzenberger; Karen Bearss; Amy Gibson Nitza; Lisa A. Fisher; Bernadette Henry

January 1, 2000

Consequences of inhibition of plasma carboxypeptidase B on in vivo thrombolysis, thrombosis and hemostasis

Fibrinolysis and Proteolysis, ISSN: 13690191

Refino; Leo Deguzman; Schmitt; Rowena Smyth; Surinc Er Jeet; Michael T. Lipari; Dan L. Eaton; Bunting

January 1, 2000

Anticalins versus antibodies: Made-to-order binding proteins for small molecules

Chemistry and Biology, ISSN: 10745521

Gregory A. Weiss; Henry B. Lowman

January 1, 2000

VEGF enhances angiogenesis and promotes blood-brain barrier leakage in the ischemic brain

Journal of Clinical Investigation, ISSN: 00219738

Zheng Gang Zhang; Li Zhang; Quan Jiang; Ruilan Zhang; Kenneth Davies; Cecylia Powers; Nicholas Van Bruggen; Michael Chopp

January 1, 2000

Anti-VEGF antibody treatment of glioblastoma prolongs survival but results in increased vascular cooption

Neoplasia (United States), ISSN: 15228002

James L. Rubenstein; Jin Kim; Tomoko Ozawa; Michael Zhang; Manfred Westphal; Dennis F. Deen; Shuman

January 1, 2000

The effects of a histidine residue on the C-terminal side of an asparaginyl residue on the rate of deamidation using model pentapeptides

Journal of Pharmaceutical Sciences, ISSN: 00223549

Chimanlall Goolcharran; Lori L. Stauffer; Cleland; Ronald T. Borchardt

January 1, 2000

Combining enhanced metabolic labeling with immunoblotting to detect interactions of endogenous cellular proteins

BioTechniques, ISSN: 07366205

Frank C. Kischkel; Avi Ashkenazi

January 1, 2000

Mapping the phosphorylation sites of proteins using on-line immobilized metal affinity chromatography/capillary electrophoresis/electrospray ionization multiple stage tandem mass spectrometry

Rapid Communications in Mass Spectrometry, ISSN: 09514198

Ping Cao; Stults

January 1, 2000

Impact of endotoxin on UCP homolog mRNA abundance, thermoregulation, and mitochondrial proton leak kinetics

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Yu; Jamie L. Barger; Bert B. Boyer; Martin D. Brand; Pan; Adams

January 1, 2000

Experimental histoplasmosis in mice treated with anti-murine interferon- γ antibody and in interferon-γ gene knockout mice

Microbes and Infection, ISSN: 12864579

Karl V. Clemons; Darbonne; John T. Curnutte; Raymond A. Sobel; David A. Stevens

January 1, 2000

Recombinant decorsin: Dynamics of the RGD recognition site

Protein Science, ISSN: 09618368

Andrzej M. Krezel; Jana S. Ulmer; Gerhard Wagner; Lazarus

January 1, 2000

Application of microwave technology to the processing and immunolabeling of plastic-embedded and cryosections

Journal of Histochemistry and Cytochemistry, ISSN: 00221554

Linda Rangell; Gilbert-Andre Keller

January 1, 2000

Characterization of novel UCP5/BMCP1 isoforms and differential regulation of UCP4 and UCP5 expression through dietary or temperature manipulation

FASEB Journal, ISSN: 08926638

Xing Xian Yu; Mao; Zhong; Peter Schow; Brush; Steve Sherwood; Adams; Pan

January 1, 2000

Development of Herceptin

Breast Disease, ISSN: 08886008

Paul J. Carter; Brian M. Fendly; Gail D. Lewis; Mark X. Sliwkowski

January 1, 2000

Ligand-binding sites in Ig-like domains of receptor tyrosine kinases

Journal of Molecular Medicine, ISSN: 09462716

Wiesmann; Yves A. Muller; De Vos

January 1, 2000

The impact of recombinant human growth hormone treatment during chronic renal insufficiency on renal transplant recipients

Journal of Pediatrics, ISSN: 00223476

Richard N. Fine; E. Kenneth Sullivan; Joyce Kuntze; Sandra L. Blethen; Edward C. Kohaut

January 1, 2000

Choice of microcentrifuge tubes influences T cell proliferation assay

BioTechniques, ISSN: 07366205

Wei; Mrsny; Blumberg; Fried; Andreas D. Christ

January 1, 2000

New approaches to antigen delivery

Critical Reviews in Therapeutic Drug Carrier Systems, ISSN: 07434863

David FitzGerald; Mrsny

January 1, 2000

Identification of a receptor for BLyS demonstrates a crucial role in humoral immunity

Nature Immunology, ISSN: 15292908

Minhong Yan; Scot A. Marsters; Iqbal S. Grewal; Hua Wang; Avi Ashkenazi; Vishva M. Dixit

December 23, 1999

Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways

Oncogene, ISSN: 09509232

Songqing Na; Baiyong Li; Iqbal S. Grewal; Hervé Enslen; Roger J. Davis; Jeffrey H. Hanke; Richard A. Flavell

December 23, 1999

Treatment of allergic asthma with monoclonal anti-IgE antibody

New England Journal of Medicine, ISSN: 00284793

Henry Milgrom; Robert B. Fick Jr.; John Q. Su; Reimann; Robert K. Bush; Marc Watrous; W. James Metzger

December 17, 1999

Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP

Journal of Biological Chemistry, ISSN: 00219258

Somasekar Seshagiri; Domagoj Vucic; James Lee; Vishva M. Dixit

December 17, 1999

Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk

Journal of Biological Chemistry, ISSN: 00219258

Jingwei Meng; Jennifer L. Glick; Paul G. Polakis; Patrick J. Casey

December 10, 1999

Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase

Human Genetics, ISSN: 03406717

Noack; Julie Rae; Andrew R. Cross; José Muñoz; Siham Salmen; José A. Mendoza; Nineth Rossi; John T. Curnutte; Heyworth

December 7, 1999

Overexpression of thioredoxin h leads to enhanced activity of starch debranching enzyme (pullulanase) in barley grain

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Myeong-Je Cho; Joshua H. Wong; Corina Marx; Jiang; Peggy G. Lemaux; Bob B. Buchanan

December 5, 1999

Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand

Virology, ISSN: 00426822

Berman; Wei Huang; Riddle; Gray; Wrin; Vennari; Johnson; Michael Klaussen; Prashad; Christiane Köhne; Christina De Wit; Timothy Gregory

December 1, 1999

Chapter 3.1.10 Targeting genes associated with mammalian behavior: past mistakes and future solutions

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Gerlai

December 1, 1999

Preface. Behavioral neurogenetics: the new synthesis

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Wim E. Crusio; Gerlai

December 1, 1999

Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli

Journal of Cell Science, ISSN: 00219533

Donna Stone; Maximilien Murone; Shiuh-Ming Luoh; Weilan Ye; Armanini; Austin L. Gurney; Phillips; Brush; Goddard; Frederic J. De Sauvage; Rosenthal

December 1, 1999

Clinical applications of angiogenic growth factors and their inhibitors

Nature Medicine, ISSN: 10788956

Napoleone Ferrara; Kari Alitalo

December 1, 1999

Chapter 3.2.7 Protein targeting in the functional analysis of EphA receptors: the use of immunoadhesins

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Gerlai; Natasha Shinsky; Shih; P. Mickey Williams; Jane Winer; Armanini; Paul Moran; Cairns; Winslow; Gao; Phillips

December 1, 1999

Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system

Journal of Cell Science, ISSN: 00219533

Andrew D. Rogove; Chia-Jen Siao; Keyt; Sidney Strickland; Stella E. Tsirka

December 1, 1999

Recovery of severe sciatica

Spine, ISSN: 03622436

Federico Balagué; Margareta Nordin; Ali Sheikhzadeh; Anne-Catherine Echegoyen; Helena Brisby; Henri Marcel Hoogewoud; Pam Fredman; Mary Louise Skovron

December 1, 1999

Chapter 2.2.4 Application of real-time RT-PCR for quantification of gene expression

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Jane Winer; Natasha Shinsky; Gerlai; P. Mickey Williams

December 1, 1999

Chapter 4.1 Ethological approaches in behavioral neurogenetic research

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Gerlai

December 1, 1999

Chapter 3.2.6 The use of immunoadhesins in neurobiology

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

David L. Shelton

December 1, 1999

Control of apoptosis signaling by Apo2 ligand

Recent Progress in Hormone Research, ISSN: 00799963

Scot A. Marsters; Pitti; James P. Sheridan; Avi Ashkenazi

December 1, 1999

Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro

RNA, ISSN: 13558382

Craig A. Smibert; Yung S. Lie; Wendy Shillinglaw; William J. Henzel; Paul M. Macdonald

December 1, 1999

Prolonging cell-free protein synthesis with a novel ATP regeneration system

Biotechnology and Bioengineering, ISSN: 00063592

Dong-Myung Kim; James R. Swartz

December 1, 1999

Chapter 2.1.8 Mutagenesis in zebra fish: studying the brain dopamine systems

Techniques in the Behavioral and Neural Sciences, ISSN: 09210709

Guo; Wolfgang Driever; Rosenthal

December 1, 1999

Role of oestrogen therapy in the management of short stature in Turner syndrome

Acta Paediatrica, International Journal of Paediatrics, Supplement, ISSN: 08035326

Chernausek; Kenneth M. Attie

December 1, 1999

Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset the ATLANTIS study: A randomized controlled trial

JAMA - Journal of the American Medical Association, ISSN: 00987484

Wayne M. Clark; Stanley Wissman; Gregory W. Albers; Jack H. Jhamandas; Kenneth Madden; Scott Hamilton

December 1, 1999

Secretion of glycosylation site mutants can be rescued by the signal/pro sequence of tissue plasminogen activator

Journal of Cellular Biochemistry, ISSN: 07302312

Christiane Köhne; Johnson; Sabrina Tom; Peers; Richard L. Gehant; Hotaling; Dave Brousseau; Thomas Ryll; Judy Fox; Steven M. Chamow; Berman

December 1, 1999

Validation of a rat pheochromocytoma (PC12)-based cell survival assay for determining biological potency of recombinant human nerve growth factor

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Hélène Gazzano-Santoro; Chen; Barbara Casto; Chu; Ellen Gilkerson; Mukku; Eleanor Canova-Davis; Claire Kotts

November 26, 1999

Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas

FEBS Letters, ISSN: 00145793

Yoshiko Chuman; Ann-Charlotte Bergman; Takayuki Ueno; Shin'Ichi Saito; Kazuyasu Sakaguchi; Ayodele A. Alaiya; Bo Franzén; Tomas Bergman; David Arnott; Gert Auer; Ettore Appella; Hans Jörnvall; Stig Linder

November 25, 1999

Hedgehog signal transduction: From flies to vertebrates

Experimental Cell Research, ISSN: 00144827

Maximilien Murone; Rosenthal; Frederic J. De Sauvage

November 25, 1999

Establishing equivalence by showing that a specified percentage of the effect of the active control over placebo is maintained

Journal of Biopharmaceutical Statistics, ISSN: 10543406

Holmgren

November 19, 1999

RIP2 is a Raf1-activated mitogen-activated protein kinase kinase

Journal of Biological Chemistry, ISSN: 00219258

Tony A. Navas; Daryl T. Baldwin; Stewart

November 19, 1999

Locoregional Apo2L/TRAIL eradicates intracranial human malignant glioma xenografts in athymic mice in the absence of neurotoxicity

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Wilfried Roth; Stefan Isenmann; Ulrike Naumann; Sebastian Kügler; Mathias Bähr; Johannes Dichgans; Avi Ashkenazi; Michael Weller

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