Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13151 - 13200 OF 15758 RESULTS

Glycerophosphorylethanolamine (GPEA) identified as an hepatocyte growth stimulator in liver extracts
Experimental Cell Research, ISSN: 00144827
Nelson; Moffat; Neil E. Jacobsen; William J. Henzel; Stults; King; Amy E. McMurtrey; Richard L. Vandlen; Steven A. Spencer
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A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Paul M. Martha Jr.; Alan D. Rogol; Johannes D. Veldhuis; Robert M. Blizzard
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Recombinant human inhibin-A administered early in the menstrual cycle alters concurrent pituitary and follicular, plus subsequent luteal, function in rhesus monkeys
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Theodore A. Molskness; Woodruff; David L. Hess; Dahl; Richard L. Stouffer
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Spray-coating of rhDNase on lactose: Effect of system design, operational parameters and protein formulation
International Journal of Pharmaceutics, ISSN: 03785173
Maa; Phuong-Anh Nguyen; Chung C. Hsu
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A negative regulatory region in the intracellular domain of the human interferon-α receptor
Journal of Biological Chemistry, ISSN: 00219258
Gibbs; Michelle Takahashi; Michel Aguet; Anan Chuntharapai
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Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics
Journal of Biological Chemistry, ISSN: 00219258
Alexandra Kalb; Horst Bluethmann; Mark Moore; Werner Lesslauer
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Confirmation by mass spectrometry of a trisulfide variant in methionyl human growth hormone biosynthesized in Escherichia coli
Analytical Chemistry, ISSN: 00032700
Eleanor Canova-Davis; Ida P. Baldonado; Chloupek; Victor Ling; Richard L. Gehant; Olson; Beth Gillece-Castro
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Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease
Journal of Neuroscience, ISSN: 02706474
Christian Winkler; Hans Sauer; Lee; Anders Bjorklund
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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
Nature, ISSN: 00280836
Donna Stone; Mary Hynes; Armanini; Todd A. Swanson; Qimin Gu; Ronald L. Johnson; Matthew P. Scott; Diane Pennica; Goddard; Phillips; Markus Noll; Joan E. Hooper; Frederic J. De Sauvage; Rosenthal
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An evaluation of the accuracy of four ELISA methods for measuring natural and recombinant human interferon-g
Journal of Immunological Methods, ISSN: 00221759
Paasch; Baron R. Reed; Rodney Keck; Bryan Sandlund; Ellen Gilkerson; Shalaby
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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David M. Holtzman; Daniela Santucci; Joshua Kilbridge; Jane Chua-Couzens; David J. Fontana; Scott E. Daniels; Johnson; Grace Chan; Yuling Sun; Elaine J. Carlson; Enrico Alleva; Charles J. Epstein; William C. Mobley
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Purification of insulin-like growth factor-I and related proteins using underivatized silica
Journal of Chromatography A, ISSN: 00219673
David H. Reifsnyder; Charles V. Olson; Etcheverry; Prashad; Stuart E. Builder
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Furilisin: A variant of subtilisin BPN' engineered for cleaving tribasic substrates
Biochemistry, ISSN: 00062960
Ballinger; Jeffrey Tom; James A. Wells
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Stable formulations of recombinant human growth hormone and interferon-γ for microencapsulation in biodegradable microspheres
Pharmaceutical Research, ISSN: 07248741
Cleland; Andrew J.S. Jones
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Design of biological equivalence programs for therapeutic biotechnology products in clinical development: A perspective
Pharmaceutical Research, ISSN: 07248741
Joyce Mordenti; Joy A. Cavagnaro; Green
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Involvement of interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: Evidence from mice lacking the murine IL-8 receptor homologue
Journal of Experimental Medicine, ISSN: 00221007
Hal E. Broxmeyer; Scott Cooper; Cacalano; Hague; Edward Bailish; Mark Moore
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Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants
Biotechnology Progress, ISSN: 87567938
Narendra B. Bam; Cleland; Theodore W. Randolph
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When perfectly HLA-matched kidneys are refused for transplant: Implications for a national cooperative sharing system
Journal of the American College of Surgeons, ISSN: 10727515
Mary D. Ellison; Timothy J. Breen; Darcy B. Davies; Erick B. Edwards; Richard J. Mahoney; Otis P. Daily; Douglas J. Norman
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Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Judy Fox; Hotaling; Craig Struble; Jane Ruppel; Dorothy J. Bates; Schoenhoff
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L-Selectin Binds to P-Selectin Glycoprotein Ligand-1 on Leukocytes: Interactions between the Lectin, Epidermal Growth Factor, and Consensus Repeat Domains of the Selectins Determine Ligand Binding Specificity
Journal of Immunology, ISSN: 00221767
Lili Tu; Anjun Chen; Martha D. Delahunty; Kevin L. Moore; Susan R. Watson; Rodger P. McEver; Thomas F. Tedder
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Interleukin-8 (IL-8), melanoma growth-stimulatory activity, and neutrophil-activating peptide selectively mediate priming of the neutrophil NADPH oxidase through the type A or type B IL-8 receptor
Journal of Biological Chemistry, ISSN: 00219258
Green; Anan Chuntharapai; John T. Curnutte
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On-line simultaneous monitoring of ammonia and glutamine in a hollow-fiber reactor using flow injection analysis
Journal of Biotechnology, ISSN: 01681656
Stoll; Ruffieux; Schneider; Von Stockar; Ian W. Marison
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The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21- activated kinases
Journal of Biological Chemistry, ISSN: 00219258
Jiabing Ding; Ulla G. Knaus; Jian P. Lian; Bokoch; John A. Badwey
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Regulation of WT1 by phosphorylation: Inhibition of DNA binding, alteration of transcriptional activity and cellular translocation
EMBO Journal, ISSN: 02614189
Ying Ye; Baisakhi Raychaudhuri; Austin L. Gurney; Christine E. Campbell; Bryan R. G. Williams
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Defective B Cell Development in Snell Dwarf (dw/dw) Mice Can Be Corrected by Thyroxine Treatment
Journal of Immunology, ISSN: 00221767
Encarnacion Montecino-Rodriguez; Ross Clark; Anne Johnson; Linda Collins; Kenneth Dorshkind
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Therapeutic angiogenesis following arterial gene transfer of vascular endothelial growth factor in a rabbit model of hindlimb ischemia
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Satoshi Takeshita; Lawrence Weir; Dongfen Chen; Lu P. Zheng; Reimer Riessen; Christophe Bauters; James F. Symes; Napoleone Ferrara; Jeffrey M. Isner
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The cellular patterns of BDNF and trkB expression suggest multiple roles of BDNF during Xenopus visual system development
Developmental Biology, ISSN: 00121606
Susana Cohen-Cory; Escandon; Scott E. Fraser
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Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: Implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Jan L. Shifren; Jennifer F. Tseng; Charles J. Zaloudek; Isabelle P. Ryan; Meng; Napoleone Ferrara; Robert B. Jaffe; Robert N. Taylor
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Changes in body composition of human immunodeficiency virus-infected males receiving insulin-like growth factor I and growth hormone
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Ellis; Lee; Pivarnik; Julie Bukar; Gesundheit
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Structural stability of disulfide mutants of basic pancreatic trypsin inhibitor: A molecular dynamics study
Proteins: Structure, Function and Bioinformatics, ISSN: 08873585
Celia A. Schiffer; Wilfred F. Van Gunsteren
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Gene transfer of naked DNA encoding for three isoforms of vascular endothelial growth factor stimulates collateral development in vivo
Laboratory Investigation, ISSN: 00236837
Satoshi Takeshita; Yukio Tsurumi; Thierry Couffinahl; Takayuki Asahara; Christophe Bauters; James F. Symes; Napoleone Ferrara; Jeffrey M. Isner
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Adenosine mediates hypoxic induction of vascular endothelial growth factor in retinal pericytes and endothelial cells
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Hitoshi Takagi; George L. King; Gregory S. Robinson; Napoleone Ferrara; Lloyd Paul Aiello
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Monoclonal antiidiotypic antibodies neutralize cytotoxic effects of anti-αGal antibodies
Transplantation, ISSN: 00411337
Koren; Franko Milotic; Francisca A. Neethling; Mirna Koscec; David T.W. Fei; Takaaki Kobayashi; Shigeki Taniguchi; David K.C. Cooper
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Replacing succinate with glycolate buffer improves the stability of lyophilized interferon-
International Journal of Pharmaceutics, ISSN: 03785173
Lam; Henry R. Costantino; David E. Overcashier; Tue H. Nguyen; Chung C. Hsu
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Natural killer cells, adhesion and tumor angiogenesis
Nature Medicine, ISSN: 10788956
Napoleone Ferrara
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Long-acting growth hormones produced by conjugation with polyethylene glycol
Journal of Biological Chemistry, ISSN: 00219258
Ross Clark; Olson; Fuh; Marian; Deborah L. Mortensen; Glen Teshima; Suh Chang; Chu; Mukku; Eleanor Canova-Davis; Todd C. Somers; Cronin; Winkler; James A. Wells
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Solvent isotope effects in H2O-D2O mixtures (proton inventories) on serine-protease-catalyzed hydrolysis reactions. Influence of oxyanion hole interactions and medium effects
Journal of the American Chemical Society, ISSN: 00027863
Chang; Chiang; Guo; Kresge; Mathew; Powell; James A. Wells
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Characterization of a novel member of the macrophage mannose receptor type C lectin family
Journal of Biological Chemistry, ISSN: 00219258
Kai Wu; Jean Yuan; Lasky
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The second immunoglobulin-like domain of the VEGF tyrosine kinase receptor Flt-1 determines ligand binding and may initiate a signal transduction cascade
EMBO Journal, ISSN: 02614189
Terri Davis-Smyth; Helen Chen; Jeanie Park; Presta; Napoleone Ferrara
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Mucosal Addressin Cell Adhesion Molecule-1: A Structural and Functional Analysis Demarcates the Integrin Binding Motif
Journal of Immunology, ISSN: 00221767
Joanne L. Viney; Susan Jones; Chiu; Bill Lagrimas; Renz; Presta; Jackson; Kenneth J. Hillan; Sandra Lew; Fong
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Mucosal Addressin Cell Adhesion Molecule-1: A Structural and Functional Analysis Demarcates the Integrin Binding Motif
Journal of Immunology, ISSN: 00221767
Joanne L. Viney; Susan Jones; Chiu; Bill Lagrimas; Renz; Presta; Jackson; Kenneth J. Hillan; Sandra Lew; Sherman Fong
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Long-term survival of solid organ allografts by brief anti-lymphocyte function-associated antigen-1 monoclonal antibody monotherapy
Transplantation, ISSN: 00411337
Eric K. Nakakura; Randi A. Shorthouse; Biru Zheng; McCabe; Paula Jardieu; Randall E. Morris
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Analysis of Acidic Oligosaccharides and Glycopeptides by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry
Analytical Chemistry, ISSN: 00032700
Damon I. Papac; Anissa Wong; Andrew J.S. Jones
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Capillary isoelectric focusing and sodium dodecyl sulfate - Capillary gel electrophoresis of recombinant humanized monoclonal antibody HER2
Journal of Chromatography A, ISSN: 00219673
Glenn Hunt; Kathy Moorhouse; Chen
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Separation of recombinant human growth hormone from Escherichia coli cell pellet extract by capillary zone electrophoresis
Journal of Chromatography A, ISSN: 00219673
McNerney; Sarah K. Watson; Jek H. Sim; Robert L. Bridenbaugh
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Examination of capillary zone electrophoresis, capillary isoelectric focusing and sodium dodecyl sulfate capillary electrophoresis for the analysis of recombinant tissue plasminogen activator
Journal of Chromatography A, ISSN: 00219673
Jacqueline M. Thorne; Wolfgang K. Goetzinger; Chen; Kathy Moorhouse; Karger
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Comparison of ampholytes used for slab gel and capillary isoelectric focusing of recombinant tissue-type plasminogen activator glycoforms
Journal of Chromatography A, ISSN: 00219673
Chen; Carina A. Rickel; Flanigan; Glenn Hunt; Kathy Moorhouse
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Fmoc-based synthesis of glycolate ester peptides for the assembly of de novo designed multimeric proteins using subtiligase
Tetrahedron Letters, ISSN: 00404039
Daniel J. Suich; Ballinger; James A. Wells; William F. DeGrado
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Identification of ligand binding determinants in the somatostatin receptor subtypes 1 and 2
Journal of Biological Chemistry, ISSN: 00219258
George Liapakis; Daniel Fitzpatrick; Carl Hoeger; Jean Rivier; Richard L. Vandlen; Terry Reisine
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Diverging signal transduction pathways activated by interleukin 8 (IL- 8) and related chemokines in human neutrophils. IL-8 and Gro-α differentially stimulate calcium influx through IL-8 receptors A and B
Journal of Biological Chemistry, ISSN: 00219258
Bassam B. Damaj; Shaun R. McColl; Kuldeep Neote; Caroline A. Heber; Paul H. Naccache
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