Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13351 - 13400 OF 15806 RESULTS

February 16, 1996

The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution

Journal of Molecular Biology, ISSN: 00222836

Yves A. Muller; Ultsch; De Vos

February 15, 1996

HGF and HGF receptor expresion in the lacrimal gland

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson

February 15, 1996

Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation

Circulation, ISSN: 00097322

Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas

February 15, 1996

Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson

February 15, 1996

Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth

Cancer Research, ISSN: 00085472

Ostap Melnyk; Shuman; K.Jin Kim

February 15, 1996

Macrophage-mediated apoptosis in the developing mouse eye

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang

February 13, 1996

Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity

Biochemistry, ISSN: 00062960

Cacia; Rodney Keck; Presta; John Frenz

February 10, 1996

A model for metal affinity protein precipitation

Journal of Colloid and Interface Science, ISSN: 00219797

Harish V. Iyer; Todd M. Przybycien

February 9, 1996

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

Cell, ISSN: 00928674

Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber

February 8, 1996

High level secretion of a humanized bispecific diabody from Escherichia coli

Bio/Technology, ISSN: 0733222X

Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter

February 1, 1996

Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin

Journal of Experimental Medicine, ISSN: 00221007

Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore

February 1, 1996

The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation

Laboratory Investigation, ISSN: 00236837

Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

February 1, 1996

Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods

Electrophoresis, ISSN: 01730835

Kathy Moorhouse; Carina A. Rickel; Chen

February 1, 1996

Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival

Development (Cambridge), ISSN: 09501991

Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien

February 1, 1996

Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma

Cell Growth and Differentiation, ISSN: 10449523

Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott

January 31, 1996

Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice

International Immunology, ISSN: 09538178

Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel

January 15, 1996

Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression

Journal of Clinical Investigation, ISSN: 00219738

Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky

January 15, 1996

Hematopoietic defects in mice lacking the sialomucin CD34

Blood, ISSN: 00064971

Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky

January 11, 1996

Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas

January 11, 1996

Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles

Journal of Cardiovascular Pharmacology, ISSN: 01602446

Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith

January 9, 1996

Binding in the growth hormone receptor complex

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

James A. Wells

January 4, 1996

Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy

Carbohydrate Research, ISSN: 00086215

Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell

January 1, 1996

Hematopoietic receptor complexes

Annual Review of Biochemistry, ISSN: 00664154

James A. Wells; De Vos

January 1, 1996

Trends in mortality in older women: Findings from the Nun Study

Journals of Gerontology - Series B Psychological Sciences and Social Sciences, ISSN: 10795014

Steven M. Butler; David A. Snowdon

January 1, 1996

RhNGF slow unfolding is not due to proline isomerization: Possibility of a cystine knot loop-threading mechanism

Protein Science, ISSN: 09618368

Linda R. De Young; Louis E. Burton; Jun Liu; Powell; Charles H. Schmelzer; Nicholas J. Skelton

January 1, 1996

The role of protein-solvent interactions in protein unfolding

Current Opinion in Biotechnology, ISSN: 09581669

Celia A. Schiffer; Volker Dötsch

January 1, 1996

Technical and regulatory hurdles in delivery aspects of macromolecular drugs

Journal of Controlled Release, ISSN: 01683659

Andrew J.S. Jones; Cleland

January 1, 1996

Cardiac fibroblasts produce leukemia inhibitory factor and endothelin, which combine to induce cardiac myocyte hypertrophy in vitro

Endocrine, ISSN: 15590100 1355008X

King; Lai; Jane Winer; Luis; Randy Yen; Jeff Hooley; Mickey Williams; Mather

January 1, 1996

Inhibitory effect of sugars and polyols on the metal-catalyzed oxidation of human relaxin

Journal of Pharmaceutical Sciences, ISSN: 00223549

Shihong Li; Thomas W. Patapoff; Tue H. Nguyen; Ronald T. Borchardt

January 1, 1996

Vascular endothelial growth factor is sufficient to produce iris neovascularization and neovascular glaucoma in a nonhuman primate

Archives of Ophthalmology, ISSN: 00039950

Michael J. Tolentino; Joan W. Miller; Evangelos S. Gragoudas; Klio Chatzistefanou; Napoleone Ferrara; Anthony P. Adamis

January 1, 1996

Expression and characterization of cysteine-modified variants of an amino-terminal fragment of bactericidal/permeability-increasing protein

Protein Expression and Purification, ISSN: 10465928

Arnold H. Horwitz; Scott Leigh; Susan L. Abrahamson; Hélène Gazzano-Santoro; Pei-Syan Liu; Robert E. Williams; Stephen F. Carroll; Georgia Theofan

January 1, 1996

Memory and the effect of cold shock in the water maze in S100β transgenic mice

Physiology and Behavior, ISSN: 00319384

Jessica K. Roder; John C. Roder; Gerlai

January 1, 1996

Endogenous cardiac vasoactive factors modulate endothelin production by cardiac fibroblasts in culture

Endocrine, ISSN: 15590100 1355008X

King; Jane Winer; Mather

January 1, 1996

Effects of reducing sugars on the chemical stability of human relaxin in the lyophilized state

Journal of Pharmaceutical Sciences, ISSN: 00223549

Shihong Li; Thomas W. Patapoff; David E. Overcashier; Chung C. Hsu; Tue H. Nguyen; Ronald T. Borchardt

January 1, 1996

Tumor necrosis factor promotes motor functional recovery in crushed peripheral nerve

Neurochemistry International, ISSN: 01970186

Long-En Chen; Anthony V. Seaber; Grace H.W. Wong; Urbaniak Jamesr

January 1, 1996

Relative toxicity of di(2-ethylhexyl) sebacate and related compounds in an in vivo hamster bioassay

Inhalation Toxicology, ISSN: 08958378

Joseph D. Brain; Blanchard; Heyder; Susan F. Wolfthal; Barbara D. Beck

January 1, 1996

Results of a prospective, randomized trial of surgery versus thrombolysis for occluded lower extremity bypass grafts

American Journal of Surgery, ISSN: 00029610

Anthony J. Comerota; Fred A. Weaver; James Hosking D; Froehlich; Folander Hal; Barry Sussman; Ken Rosenfield

January 1, 1996

Induced expression of the new cytokine, activin A, in human monocytes: Inhibition by glucocorticoids and retinoic acid

Immunology, ISSN: 00192805

Yu; Shao; Frigon Jr.; James A. Lofgren; Ralph H. Schwall

January 1, 1996

Effects of 14-day infusions of growth hormone and/or insulin-like growth factor I on the obesity of growing Zucker rats

Endocrinology, ISSN: 00137227

Dubuis; Deal; Tsagaroulis; Ross Clark; Van Vliet

January 1, 1996

Cardiotrophin-1, a cytokine present in embryonic muscle, supports long- term survival of spinal motoneurons

Neuron, ISSN: 08966273

Diane Pennica; Vilma Arce; Todd A. Swanson; Richard Vejsada; Richard A. Pollock; Armanini; Dudley; Phillips; Rosenthal; Ann C. Kato; Christopher E. Henderson

January 1, 1996

Cardiotrophin-1: A multifunctional cytokine that signals via LIF receptor-gp130 dependent pathways

Cytokine and Growth Factor Reviews, ISSN: 13596101

Diane Pennica; William I. Wood; Kenneth R. Chien

January 1, 1996

The bglX gene located at 47.8 min on the Escherichia coli chromosome encodes a periplasmic β-glucosidase

Microbiology, ISSN: 13500872

Yang; Shiuh-Ming Luoh; Goddard; Dorothea Reilly; William J. Henzel; Bass

January 1, 1996

Pulmonary and mediastinal metastases of a vaccination-site sarcoma in a cat

Veterinary Pathology, ISSN: 03009858

Daniel G. Rudmann; Van Alstine; Doddy; Sandusky; Barkdull; Evan B. Janovitz

January 1, 1996

Establishment of Schwann cell lines from normal adult and embryonic rat dorsal root ganglia

Journal of Neuroscience Methods, ISSN: 01650270

Li; Mark X. Sliwkowski; Jeannie Lo; Mather

January 1, 1996

'Knobs-into-holes' engineering of antibody C(H)3 domains for heavy chain heterodimerization

Protein Engineering, ISSN: 02692139

John B.B. Ridgway; Presta; Paul J. Carter

January 1, 1996

Liquid-liquid emulsification by static mixers for use in microencapsulation

Journal of Microencapsulation, ISSN: 02652048

Maa; Chung C. Hsu

January 1, 1996

Testicular germ cell populations in the adult rat after continuous in-vivo testicular infusion of inhibin-A and activin-A

International Journal of Andrology, ISSN: 01056263

Adeeko; Dunne; Mather; Alison Moore; Morris

January 1, 1996

Adaptation to ozone in rats and its association with ascorbic acid in the lung

Fundamental and Applied Toxicology, ISSN: 02720590

Wiester; Tepper; Winsett; Crissman; Richards; Costa

January 1, 1996

Genetic absence of γ-interferon delays but does not prevent diabetes in NOD mice

Diabetes, ISSN: 00121797

Hultgren; Huang; Noel Dybdal; Stewart

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