Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9951 - 10000 OF 15583 RESULTS

Randomized, Double-Masked, Sham-Controlled Trial of Ranibizumab for Neovascular Age-related Macular Degeneration: PIER Study Year 1
American Journal of Ophthalmology, ISSN: 00029394
Carl D. Regillo; David M. Brown; Prema Abraham; Huibin Yue; Tsontcho Ianchulev; Susan Schneider; Naveed Shams
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Personalized medicine complicates medical decision-making
Managed Care, ISSN: 10623388
Thomas Morrow
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Height velocity targets from the national cooperative growth study for first-year growth hormone responses in short children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Bert Bakker; James W. Frane; Henry Anhalt; Barbara M. Lippe; Rosenfeld
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Long-term safety of recombinant human growth hormone in Turner syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Katrina Bolar; Andrew R. Hoffman; Thomas J. Maneatis; Barbara M. Lippe
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T-cell lymphomas in T-cell-specific Pten-deficient mice originate in the thymus
Leukemia, ISSN: 14765551 08876924
Thijs Hagenbeek; Hergen Spits
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Recently-approved sapropterin reduces phenylalanine levels
Managed Care, ISSN: 10623388
Thomas Morrow
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Compliance and persistence in pediatric and adult patients receiving growth hormone therapy
Endocrine Practice, ISSN: 1530891X
Rosenfeld; Bert Bakker
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Assessing productivity loss and activity impairment in severe or difficult-to-treat asthma
Value in Health, ISSN: 15244733 10983015
Hubert Chen; Paul D. Blanc; Mary Lou Hayden; Eugene R. Bleecker; Chawla; June H. Lee
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Insurance status and asthma-related health care utilization in patients with severe asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Anju T. Peters; Julie C. Klemens; Tmirah Haselkorn; Weiss; Leslie C. Grammer; June H. Lee; Hubert Chen
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Ranibizumab for macular edema due to retinal vein occlusions: Implication of VEGF as a critical stimulator
Molecular Therapy, ISSN: 15250024 15250016
Peter A. Campochiaro; Gulnar Hafiz; Syed Mahmood Shah; Quan Dong Nguyen; Howard Ying; Diana V. Do; Edward Quinlan; Ingrid Zimmer-Galler; Julia A. Haller; Sharon D. Solomon; Jennifer U. Sung; Yasmin Hadi; Kashif A. Janjua; Nida Jawed; David F. Choy; Joseph R. Arron
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A key claudin extracellular loop domain is critical for epithelial barrier integrity
American Journal of Pathology, ISSN: 00029440
Mrsny; G. Thomas Brown; Kirsten Gerner-Smidt; Andre G. Buret; Jon B. Meddings; Quan; Michael Koval; Asma Nusrat
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Blockade of CD11a by efalizumab in psoriasis patients induces a unique state of T-cell hyporesponsiveness
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Emma Guttman-Yassky; Yulia Vugmeyster; Michelle A. Lowes; Francesca Chamian; Toyoko Kikuchi; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Brisdell Hunte; Howell; Wolfgang Dummer; Bodary; James G. Krueger
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Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results
American Journal of Ophthalmology, ISSN: 00029394
Andrew N. Antoszyk; Lisa Tuomi; Carol Chung; Angele Singh
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Ten-year outcomes following traumatic brain injury: A population-based cohort
Brain Injury, ISSN: 1362301X 02699052
Cameron; David M. Purdie; Kliewer; Rod J. McClure
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Prediction of the possibility of the second peak of drug plasma concentration time curve after iv bolus administration from the standpoint of the traditional multi-compartmental linear pharmacokinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Summary statement novel agents in the treatment of lung cancer: Fifth Cambridge conference assessing opportunities for combination therapy
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Thomas J. Lynch; George R. Blumenschein; Jeff A. Engelman; Igor Espinoza-Delgado; Ramaswamy Govindan; Jeffrey H. Hanke; Nasser H. Hanna; John V. Heymach; Fred R. Hirsch; Pasi A. Jänne; Rogerio C. Lilenbaum; Ronald B. Natale; Gregory J. Riely; Lecia V. Sequist; Geoffrey I. Shapiro; Alice T. Shaw; Frances A. Shepherd; Mark A. Socinski; A Gregory Sorensen; Heather A. Wakelee; Aaron Weitzman
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Stopping replication, at the beginning
Nature Chemical Biology, ISSN: 15524469 15524450
Peter K Jackson
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Synthesis of a cross-bridged cyclam derivative for peptide conjugation and 64Cu radiolabeling
Bioconjugate Chemistry, ISSN: 10431802
C. Andrew Boswell; Celeste A. S. Regino; Kwamena E. Baidoo; Karen J. Wong; Ambika Bumb; Heng Xu; Diane E. Milenic; James A. Kelley; Christopher C. Lai; Martin W. Brechbiel
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Evaluation of hydrate-screening methods
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yonc Cui; Erica Yao
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The Notch pathway in prostate development and cancer
Differentiation, ISSN: 14320436 03014681
Kevin G. Leong; Gao
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15 Capillary electrophoresis and bioanalysis
Separation Science and Technology, ISSN: 01496395
Oscar Salas-Solano; Chantal Felten
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Anti-CD22-MCC-DM1 and MC-MMAF conjugates: Impact of assay format on pharmacokinetic parameters determination
Bioconjugate Chemistry, ISSN: 10431802
Jean-Philippe Stephan; Pamela Chan; Chien C. Lee; Nelson; J. Michael Elliott; Charity Bechtel; Helga Raab; David Xie; Jon Akutagawa; Jakub Baudys; Ola M. Saad; Saileta Prabhu; Wai Lee T. Wong; Richard L. Vandlen; Fred Jacobson; Allen Ebens
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The complex inter-relationships between protein flexibility and stability
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Tim J. Kamerzell; C. Russell Middaugh
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The safety of bone allografts used in dentistry: A review
Journal of the American Dental Association, ISSN: 00028177
Dan Holtzclaw; Nicholas Toscano; Lisa Eisenlohr; Don Callan
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Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus
Nature Genetics, ISSN: 15461718 10614036
Robert R. Graham; Chris Cotsapas; Leela R. L. Davies; Rachel Hackett; Christopher J. Lessard; Joanlise M. Leon; Noel Burtt; Candace Guiducci; Melissa Parkin; Casey Gates; Robert M. Plenge; Timothy W. Behrens; Joan E. Wither; John D. Rioux; Fortin; Deborah S. Cunninghame Graham; Andrew K. Wong; Timothy J. Vyse; Mark J. Daly; David Altshuler; Kathy L. Moser; Patrick M. Gaffney
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Racial disparities in asthma-related health outcomes in severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 15344436 10811206
Tmirah Haselkorn; June H. Lee; David R. Mink; Weiss
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Reversible self-association of a concentrated monoclonal antibody solution mediated by fab-fab interaction that impacts solution viscosity
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sonoko Kanai; Jun Liu; Thomas W. Patapoff; Steven J. Shire
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A role of macrophage complement receptor crig in immune clearance and inflammation
Molecular Immunology, ISSN: 18729142 01615890
Jeannie Q. He; Wiesmann; Menno Van Lookeren Campagne
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Recognition of genetic factors influencing the progression of hepatitis C: Potential for personalized therapy
Molecular Diagnosis and Therapy, ISSN: 11771062
Julie R. Jonsson; David M. Purdie; Andrew D. Clouston; Elizabeth E. Powell
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Neuromyelitis optica and the optic neuritis treatment trial - Reply
Archives of Neurology, ISSN: 15383687 00039942
Craig H. Smith
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Influence of race on tolerance of platinum-based chemotherapy and clinical outcomes in women with advanced and recurrent cervical cancer: a pooled analysis of 3 Gynecologic Oncology Group studies
American Journal of Obstetrics and Gynecology, ISSN: 00029378
Steven C. Plaxe; Sandra E. Brooks; Chunquiao Tian; Jeffrey D. Bloss; David H. Moore; Harry J. Long
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Systematic comparison of gene expression between murine memory and naive B cells demonstrates that memory B cells have unique signaling capabilities
Journal of Immunology, ISSN: 15506606 00221767
Mary M. Tomayko; Shannon M. Anderson; Catherine E. Brayton; Saheli Sadanand; Natalie C. Steinel; Timothy W. Behrens; Mark J. Shlomchik
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Therapeutic anti-VEGF antibodies
Handbook of Experimental Pharmacology, ISSN: 18650325 01712004
Samantha Lien; Henry B. Lowman
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Oral involvement in primary Sjögren syndrome
Journal of the American Dental Association, ISSN: 00028177
Philip C. Fox; Simon J. Bowman; Barbara Segal; Frederick B. Vivino; Murukutla; Karen Choueiri; Sarika Ogale; Lachy McLean
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DNA microarray gene expression profile of marginal zone versus follicular B cells and idiotype positive marginal zone B cells before and after immunization with Streptococcus pneumoniae
Journal of Immunology, ISSN: 15506606 00221767
Nicholas W. Kin; Dianna Crawford; Jiabin Liu; Timothy W. Behrens; John F. Kearney
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Cytokine, chemokine, and co-stimulatory fusion proteins for the immunotherapy of solid tumors
Handbook of Experimental Pharmacology, ISSN: 18650325 01712004
Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
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Accounting for interim analyses in the assessment of program expected net present value
Drug Information Journal, ISSN: 00928615
Lee D. Kaiser; Jeffrey D. Helterbrand; Hal V. Barron
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Ranibizumab Combined With Verteporfin Photodynamic Therapy in Neovascular Age-related Macular Degeneration (FOCUS): Year 2 Results
American Journal of Ophthalmology, ISSN: 00029394
Andrew N. Antoszyk; Lisa Tuomi; Carol Y. Chung; Angele Singh
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A two-dimensional protein map of chinese hamster ovary cells
From Genome to Proteome: Advances in the Practice & Application of Proteomics,
Kathleen M. Champion; David Arnott; William J. Henrel; Sam Hermes; Weikert; Stults; Vanderlaan; Lynne Krummen
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Role of cytokine therapy in the treatment of psoriasis
Drug Discovery Today: Therapeutic Strategies, ISSN: 17406773
Yan Zheng; Ivor Caro; Wenjun Ouyang
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PADGE: Analysis of heterogeneous patterns of differential gene expression
Physiological Genomics, ISSN: 10948341 15312267
Li Li; Amitabha Chaudhuri; John Chant; Zhijun Tang
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Par3 functions in the biogenesis of the primary cilium in polarized epithelial cells
Journal of Cell Biology, ISSN: 00219525 00219525
Jeff Sfakianos; Akashi Togawa; Sandra Maday; Mike Hull; Marc Pypaert; Lloyd Cantley; Derek Toomre; Ira Mellman
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Delta-like 4/notch signaling and its therapeutic implications
Clinical Cancer Research, ISSN: 10780432
Minhong Yan; Greg D. Plowman
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Clinical poly(ADP-ribose) polymerase inhibitors for the treatment of cancer
Current Opinion in Investigational Drugs, ISSN: 14724472
Lewis; Low
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Structural insight into distinct mechanisms of protease inhibition by antibodies
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Yan Wu; Eigenbrot; Wei-Ching Liang; Scott Stawicki; Steven Shia; Bin Fan; Rajkumar Ganesan; Michael T. Lipari; Daniel Kirchhofer
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DUBA: A deubiquitinase that regulates type I interferon production
Science, ISSN: 00368075 10959203
Nobuhiko Kayagaki; Qui Phung; Salina Chan; Ruchir Chaudhari; Casey Quan; Karen M. O'Rourke; Mike Eby; Eric Pietras; Genhong Cheng; J.Fernando Bazan; Zemin Zhang; David Arnott; Vishva M. Dixit
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Bv8 regulates myeloid-cell-dependent tumour angiogenesis
Nature, ISSN: 14764687 00280836
Farbod Shojaei; Xiumin Wu; Cuiling Zhong; Lanlan Yu; Xiao Huan Liang; Jenny Yao; Dominique Blanchard; Carlos Bais; Franklin V. Peale Jr.; Nicholas Van Bruggen; Calvin Ho; Ross; Martha Tan; Richard A. D. Carano; Meng; Napoleone Ferrara
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Advances in Experimental Medicine and Biology: Foreword
Advances in Experimental Medicine and Biology, ISSN: 00652598
Vishva M. Dixit
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Efalizumab for the treatment of psoriatic arthritis
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Kim Papp; Ivor Caro; Hoi M. Leung; Marvin Garovoy; Philip J. Mease
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Safety and efficacy of additional courses of rituximab in patients with active rheumatoid arthritis: An open-label extension analysis
Arthritis and Rheumatism, ISSN: 00043591
Edward Keystone; Roy Fleischmann; Paul Emery; Daniel E. Furst; Ronald Van Vollenhoven; Joan Bathon; Maxime Dougados; Andrew Baldassare; Gianfranco Ferraccioli; Andrew Chubick; James Udell; Matthew W. Cravets; Sunil Agarwal; Simon Cooper; Fabio Magrini
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