Genentech: Publications

December 1, 2005

Heterogeneity of recombinant antibodies: Linking structure to function

Developments in Biologicals, ISSN: 14246074

Reed J. Harris

December 1, 2005

Agreement in histologic assessments of the pituitary pars intermedia in aged horses

American Journal of Veterinary Research, ISSN: 00029645

Dianne McFarlane; Lisa M. Miller; Linden E. Craig; Noel Dybdal; Perry L. Habecker; Margaret A. Miller; Jon S. Patterson; Alastair E. Cribb

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December 1, 2005

Class I FIPs, Rab11-binding proteins that regulate endocytic sorting and recycling

Methods in Enzymology, ISSN: 00766879

Elizabeth Tarbutton; Andrew A. Peden; Jagath R. Junutula; Rytis Prekeris

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December 1, 2005

Requirement for the SnoN oncoprotein in transforming growth factor β-induced oncogenic transformation of fibroblast cells

Molecular and Cellular Biology, ISSN: 02707306

Qingwei Zhu; Sonia Pearson-White; Kunxin Luo

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December 1, 2005

Targeted therapy: Wave of the future

Journal of Clinical Oncology, ISSN: 0732183X

Pegram; Pietras; Alex Bajamonde; Pam Klein; Gwendolyn Fyfe

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December 1, 2005

Development and the boundaries of the firm: A knowledge-based examination in drug development

Academy of Management 2005 Annual Meeting: A New Vision of Management in the 21st Century, AOM 2005,

Jeffrey T. Macher; Christopher S. Boerner

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December 1, 2005

Rituximab in combination with fludarabine chemotherapy in low-grade or follicular lymphoma

Journal of Clinical Oncology, ISSN: 0732183X

Myron S. Czuczman; Koryzna; Mohr; Stewart; Donohue; Blumenson; Bernstein; McCarthy; Alam; Hernandez-Ilizaliturri; Skipper; Brown; Chanan-Khan; Klippenstein; Loud; Mike K Rock; Benyunes; Grillo-Lopez; Bernstein

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December 1, 2005

Expression of HIF-1α in human tumours [5]

Journal of Clinical Pathology, ISSN: 00219746

Adrian M. Jubb; Kenneth J. Hillan

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December 1, 2005

Quantitative structure-activity relationships of methotrexate and methotrexate analogues transported by the rat multispecific resistance- associated protein 2 (rMrp2)

European Journal of Pharmaceutical Sciences, ISSN: 09280987

Chee Ng; Yun-De Xiao; Bert L. Lum; Yong-Hae Han

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December 1, 2005

Analysis of protein therapeutics by capillary electrophoresis: Applications and challenges

Developments in Biologicals, ISSN: 14246074

Stacey Ma

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December 1, 2005

Salutary effects of combining early very low-dose systemic estradiol with growth hormone therapy in girls with Turner syndrome

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X

Rosenfield; Nancy Devine; Joanne Julius Hunold; Nelly Mauras; Thomas Moshang Jr.; Allen W. Root

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November 25, 2005

Attenuating lymphocyte activity: The crystal structure of the BTLA-HVEM complex

Journal of Biological Chemistry, ISSN: 00219258

Deanne M. Compaan; Lino C. Gonzalez Jr.; Irene Tom; Kelly M. Loyet; Dan L. Eaton; Sarah G. Hymowitz

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November 22, 2005

Isolation and characterization of the B-cell marker CD20

Biochemistry, ISSN: 00062960

James A. Ernst; Hong Li; Hok Seon Kim; Nakamura; Yansura; Richard L. Vandlen

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November 21, 2005

Yersinia virulence factor YopJ acts as a deubiquitinase to inhibit NF-κB activation

Journal of Experimental Medicine, ISSN: 00221007 00221007

Honglin Zhou; Denise M. Monack; Nobuhiko Kayagaki; Ingrid E. Wertz; Jianping Yin; Beni B. Wolf; Vishva M. Dixit

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November 15, 2005

Immune thrombocytopenia associated with efalizumab therapy for psoriasis [7]

Annals of Internal Medicine, ISSN: 00034819

Theodore E. Warkentin; Paul Kwon

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November 15, 2005

Loss of the retrograde motor for IFT disrupts localization of Smo to cilia and prevents the expression of both activator and repressor functions of Gli

Developmental Biology, ISSN: 00121606

Scott R. May; Amir M. Ashique; Mattias Karlen; Baolin Wang; Yiguo Shen; Konstantinos Zarbalis; Jeremy Reiter; Johan Ericson; Andrew S. Peterson

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November 11, 2005

Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking

Journal of Biological Chemistry, ISSN: 00219258

Mark Larance; Georg Ramm; Jacqueline Stöckli; Ellen M. Van Dam; Stephanie Winata; Valerie Wasinger; Fiona Simpson; Michael Graham; Jagath R. Junutula; Michael Guilhaus; David E. James

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November 9, 2005

Concomitant administration of bevacizumab, irinotecan, 5-fluorouracil, and leucovorin: Nonclinical safety and pharmacokinetics

International Journal of Toxicology, ISSN: 10915818 1092874X

Jacques Gaudreault; Vanessa Shiu; Ann Bricarello; Brian J. Christian; Christina L. Zuch; Barbara Mounho

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November 1, 2005

Functions of adaptor protein (AP)-3 and AP-1 in tyrosinase sorting from endosomes to melanosomes

Molecular Biology of the Cell, ISSN: 10591524

Alexander C. Theos; Danièle Tenza; José A. Martina; Ilse Hurbain; Andrew A. Peden; Elena V. Sviderskaya; Abigail Stewart; Margaret S. Robinson; Dorothy C. Bennett; Daniel F. Cutler; Juan S. Bonifacino; Michael S. Marks; Graça Raposo

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November 1, 2005

Maternal embryonic leucine zipper kinase/murine protein serine-threonine kinase 38 is a promising therapeutic target for multiple cancers

Cancer Research, ISSN: 00085472

Daniel C. Gray; Adrian M. Jubb; Deborah A. Hogue; Patrick Dowd; Noelyn Kljavin; Sothy Yi; Wei Bai; Gretchen D. Frantz; Zemin Zhang; Koeppen; Frederic J. De Sauvage; David P. Davis

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November 1, 2005

Severity assessment in asthma: An evolving concept

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Mary K. Miller; Charles A. Johnson; Dave P. Miller; Yamo Deniz; Eugene R. Bleecker; Sally E. Wenzel

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November 1, 2005

Cutting edge: TRAIL deficiency accelerates hematological malignancies

Journal of Immunology, ISSN: 00221767

Nadeen Zerafa; Jennifer A. Westwood; Erika Cretney; Sally Mitchell; Waring; Manuela Iezzi; Mark J. Smyth

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November 1, 2005

IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines

Immunity, ISSN: 10747613

Jochen Schmitz; Alexander M. Owyang; Elizabeth Oldham; Yaoli Song; Erin Murphy; Terrill McClanahan; Gerard Zurawski; Mehrdad Moshrefi; Jinzhong Qin; Xiaoxia Li; Daniel M. Gorman; J.Fernando Bazan; Robert A. Kastelein

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November 1, 2005

Rapid on-membrane proteolytic cleavage for Edman sequencing and mass spectrometric identification of proteins

Electrophoresis, ISSN: 01730835

Victoria Pham; William J. Henzel; Jennie R. Lill

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November 1, 2005

VEGF as a therapeutic target in cancer

Oncology, ISSN: 00302414

Napoleone Ferrara

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November 1, 2005

Risk-based cleaning validation in biopharmaceutical API manufacturing

BioPharm International, ISSN: 1542166X

A. Hamid Mollah; Edward K. White

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November 1, 2005

A causal inference approach for constructing transcriptional regulatory networks

Bioinformatics, ISSN: 13674803 14602059

Biao Xing; Mark J. van der Laan

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November 1, 2005

The ATPase motif in RAD51D is required for resistance to DNA interstrand crosslinking agents and interaction with RAD51C

Mutagenesis, ISSN: 02678357 14643804

Aaron M. Gruver; Kristi A. Miller; Changanamkandath Rajesh; Phillip G. Smiraldo; Saravanan Kaliyaperumal; Rachel Balder; Katie M. Stiles; Joanna S. Albala; Douglas L. Pittman

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November 1, 2005

Aspirin sensitivity and severity of asthma: Evidence for irreversible airway obstruction in patients with severe or difficult-to-treat asthma

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Kimberly Mascia; Tmirah Haselkorn; Yamo Deniz; Dave P. Miller; Eugene R. Bleecker; Larry Borish

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November 1, 2005

Angiogenic inhibitors: A new therapeutic strategy in oncology

Nature Clinical Practice Oncology, ISSN: 17434254 17434262

Giampietro Gasparini; Raffaele Longo; Masakazu Toi; Napoleone Ferrara

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October 30, 2005

Involvement of α4 integrins in maintenance of cardiac sympathetic axons

Autonomic Neuroscience: Basic and Clinical, ISSN: 15660702

Kevin L. Wingerd; William C. Wayne; Jackson; Dennis O. Clegg

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October 20, 2005

Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

New England Journal of Medicine, ISSN: 00284793 15334406

Edward H. Romond; Edith A. Perez; John Bryant; Vera J. Suman; Charles E. Geyer Jr.; Nancy E. Davidson; Elizabeth Tan-Chiu; Silvana Martino; Soonmyung Paik; Peter A. Kaufman; Sandra M. Swain; Thomas M. Pisansky; Louis Fehrenbacher; Leila A. Kutteh; Victor G. Vogel; Daniel W. Visscher; Greg Yothers; Robert B. Jenkins; Ann M. Brown; Shaker R. Dakhil; Eleftherios P. Mamounas; Wilma L. Lingle; Pam Klein; James N. Ingle; Norman Wolmark

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October 17, 2005

Innate immunity against Francisella tularensis is dependent on the ASC/caspase-1 axis

Journal of Experimental Medicine, ISSN: 00221007 00221007

Sanjeev Mariathasan; David S. Weiss; Vishva M. Dixit; Denise M. Monack

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October 14, 2005

Identification of hepatocyte growth factor activator inhibitor-1B as a potential physiological inhibitor of prostasin

Journal of Biological Chemistry, ISSN: 00219258

Bin Fan; Thomas D Wu; Wei Li; Daniel Kirchhofer

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October 7, 2005

Neuroscience: EGFR activation mediates inhibition of axon regeneration by myelin and chondroitin sulfate proteoglycans

Science, ISSN: 00368075 10959203

Vuk Koprivica; Kin-Sang Cho; Jong Bae Park; Glenn Yiu; Jasvinder K. Atwal; Bryan B. Gore; Jieun A. Kim; Estelle Lin; Marc Tessier-Lavigne; Dong Feng Chen; Zhigang He

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October 4, 2005

Achieving door-to-balloon times that meet quality guidelines: How do successful hospitals do it?

Journal of the American College of Cardiology, ISSN: 07351097

Elizabeth H. Bradley; Sarah A. Roumanis; Martha J. Radford; Tashonna R. Webster; Robert L. McNamara; Jennifer A. Mattera; Barbara A. Barton; David N. Berg; Edward L. Portnay; Harry Moscovitz; Janet Parkosewich; Eric S. Holmboe; Martha Blaney; Harlan M. Krumholz

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October 1, 2005

Pathogen recognition: TLRs throw us a curve

Immunity, ISSN: 10747613

Peter Kirk; J.Fernando Bazan

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October 1, 2005

Population pharmacokinetics of trastuzumab in patients with HER2+ metastatic breast cancer

Cancer Chemotherapy and Pharmacology, ISSN: 03445704

Rene Bruno; Carla Washington; Jian-Feng Lu; Lieberman; Ludger Banken; Pam Klein

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October 1, 2005

The septin-binding protein anillin is overexpressed in diverse human tumors

Clinical Cancer Research, ISSN: 10780432

Peter A. Hall; Christopher B. Todd; Paula L. Hyland; Simon S. McDade; Grabsch; Mit Dattani; Kenneth J. Hillan; S. E. Hilary Russell

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October 1, 2005

The external RNA controls consortium: A progress report

Nature Methods, ISSN: 15487091 15491676

Shawn C. Baker; Steven R. Bauer; Richard P. Beyer; James D. Brenton; Bud Bromley; John Burrill; Helen Causton; Michael P. Conley; Rosalie Elespuru; Michael Fero; Carole Foy; James Fuscoe; Xiaolian Gao; David Lee Gerhold; Patrick Gilles; Federico Goodsaid; Xu Guo; Joe Hackett; Richard D. Hockett; Pranvera Ikonomi; Rafael A. Irizarry; Ernest S. Kawasaki; Tamma Kaysser-Kranich; Kathleen Kerr; Gretchen Kiser; Walter H. Koch; Kathy Y. Lee; Chunmei Liu; Z. Lewis Liu; Anne Lucas; Chitra F. Manohar; Garry Miyada; Zora Modrusan; Helen Parkes; Raj K. Puri; Laura Reid; Thomas B. Ryder; Marc Salit; Raymond R. Samaha; Uwe Scherf; Timothy J. Sendera; Robert A. Setterquist; Leming Shi; Richard Shippy; Jesus V. Soriano; Elizabeth A. Wagar; Janet A. Warrington; Mickey Williams; Frederike Wilmer; Mike Wilson; Paul K. Wolber; Xiaoning Wu; Renata Zadro

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October 1, 2005

TNF-related apoptosis-inducing ligand (TRAIL)/Apo2L suppresses experimental autoimmune encephalomyelitis in mice

Immunology and Cell Biology, ISSN: 08189641

Erika Cretney; Jonathan L. McQualter; Nobuhiko Kayagaki; Hideo Yagita; Claude C.A. Bernard; Iqbal S. Grewal; Avi Ashkenazi; Mark J. Smyth

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September 23, 2005

Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy

Cell, ISSN: 00928674

Sophie Pattingre; Amina Tassa; Xueping Qu; Rita Garuti; Huan Liang Xiao; Noboru Mizushima; Milton Packer; Michael D. Schneider; Beth Levine

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September 21, 2005

Inhibitory effects of interferon-γ on myocardial hypertrophy

Cytokine, ISSN: 10434666

Hongkui Jin; Wei Li; Renhui Yang; Annie Ogasawara; Hsienwie Lu; Nicholas F. Paoni

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September 19, 2005

Divergent roles of IL-23 and IL-12 in host defense against Klebsiella pneumoniae

Journal of Experimental Medicine, ISSN: 00221007

Kyle I. Happel; Patricia J. Dubin; Mingquan Zheng; Nico Ghilardi; Christie Lockhart; Lee J. Quinton; Anthony R. Odden; Judd E. Shellito; Gregory J. Bagby; Steve Nelson; Jay K. Kolls

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September 15, 2005

Preclinical antilymphoma activity of a humanized anti-CD40 monoclonal antibody, SGN-40

Cancer Research, ISSN: 00085472

Che-Leung Law; Kristine A. Gordon; John Collier; Kerry Klussman; Julie A. McEarchern; Charles G. Cerveny; Bruce J. Mixan; Wyne P. Lee; Zhonghau Lin; Patricia A. Valdez; Alan Wahl; Iqbal S. Grewal

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September 15, 2005

Novel method of generating prostate-specific Cre-loxP gene switching via intraductal delivery of adenovirus

Prostate, ISSN: 02704137

Ching Ching Leow; Xi-De Wang; Gao

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September 15, 2005

A novel method for observing proteins in vivo using a small fluorescent label and multiphoton imaging

Biochemical Journal, ISSN: 02646021

Stanley W. Botchway; Ignasi Barba; Randolf Jordan; Rebecca Harmston; Peter M. Haggie; Simon P. Williams; Alexandra M. Fulton; Anthony W. Parker; Kevin M. Brindle

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September 13, 2005

Gene targeting using a promoterless gene trap vector ("targeted trapping") is an efficient method to mutate a large fraction of genes

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Roland H. Friedel; Andrew Plump; Lu; Kerri Spilker; Christine Jolicoeur; Karen G. Wong; Tadmiri R. Venkatesh; Avraham Yaron; Mary Hynes; Bin Chen; Ami Okada; Susan K. McConnell; Helen Rayburn; Marc Tessier-Lavigne

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September 1, 2005

Mutations increasing exposure of a receptor binding site epitope in the soluble and oligomeric forms of the caprine arthritis-encephalitis lentivirus envelope glycoprotein

Virology, ISSN: 00426822

Isidro Hötzel; William P. Cheevers

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September 1, 2005

NMR methods for studying the structure and dynamics of RNA

ChemBioChem, ISSN: 14394227

Michael P. Latham; Darin J. Brown; Scott A. McCallum; Arthur Pardi

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