Scientists / Publications

Publications

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DISPLAYING 10601 - 10650 OF 15632 RESULTS

Self-association of therapeutic proteins: Implications for product development
Misbehaving Proteins: Protein (Mis)Folding, Aggregation, and Stability,
Cromwell; Chantal Felten; Heather Flores; Jun Liu; Steven J. Shire
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Phase 1 study of erlotinib HCl alone and combined with temozolomide in patients with stable or recurrent malignant glioma
Neuro-Oncology, ISSN: 15228517
Michael D. Prados; Kathleen R. Lamborn; Susan Chang; Eric Burton; Nicholas Butowski; Mary Malec; Ami Kapadia; Jane Rabbit; Margaretta S. Page; Ann Fedoroff; Dong Xie; Kelley
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Concordance between central and local laboratory HER2 testing from a community-based clinical study
Clinical Breast Cancer, ISSN: 15268209
Josina C. Reddy; Reimann; Steven M. Anderson; Pam Klein
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Somatic mutations lead to an oncogenic deletion of Met in lung cancer
Cancer Research, ISSN: 00085472
Monica Kong-Beltran; Somasekar Seshagiri; Jiping Zha; Wenjing Zhu; Kaumudi Bhawe; Nerissa Mendoza; Thomas Holcomb; Kanan Pujara; Stinson; Ling Fu; Christophe Severin; Linda Rangell; Ralph H. Schwall; Lukas Amier; Dineli Wickramasinghe; Robert Yauch
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Erratum: Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution (Journal of Pharmaceutical Sciences [2005] 94 [1928-1940] DOI: 10.1002/jps.20347)
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Jun Liu; Mary D. H. Nguyen; Andya; Steven J. Shire
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Mayo Clinic consensus statement for the use of bisphosphonates in multiple myeloma
Mayo Clinic Proceedings, ISSN: 00256196
Martha Lacy; Angela Dispenzieri; Morie A. Gertz; Philip R. Greipp; Kimberly L. Gollbach; Suzanne R. Hayman; Shaji Kumar; John A. Lust; S. Vincent Rajkumar; Stephen J. Russell; Witzig; Steven R. Zeldenrust; David Dingli; P. Lief Bergsagel; Rafael Fonseca; Craig B. Reeder; A. Keith Stewart; Vivek Roy; Robert J. Dalton; Alan B. Carr; Deepak Kademani; Eugene E. Keller; Christopher F. Viozzi; Robert A. Kyle
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Omalizumab pretreatment decreases acute reactions after rush immunotherapy for ragweed-induced seasonal allergic rhinitis
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Thomas B. Casale; William W. Busse; Joel N. Kline; Zuhair K. Ballas; Mark H. Moss; Robert G. Townley; Masoud Mokhtarani; Vicki Seyfert-Margolis; Adam Asare; Kirk Bateman; Yamo Deniz
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Pharmacokinetics/pharmacodynamics of nondepleting anti-CD4 monoclonal antibody (TRX1) in healthy human volunteers
Pharmaceutical Research, ISSN: 07248741
Chee Ng; Stefanich; Banmeet S. Anand; Fielder; Louis Vaickus
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Decreased protein C, protein S, and antithrombin levels are predictive of poor outcome in Gram-negative sepsis caused by Burkholderia pseudomallei
International Journal of Infectious Diseases, ISSN: 12019712
Steven P. LaRosa; Steven M. Opal; Barbara Utterback; Sau Chi Betty Yan; Jeffrey D. Helterbrand; Andrew J.H. Simpson; Wipada Chaowagul; Nicholas J. White; Charles J. Fisher Jr.
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Detection of T lymphocytes specific for human endogenous retrovirus K (HERV-K) in patients with seminoma
AIDS Research and Human Retroviruses, ISSN: 08892229
Seth Rakoff-Nahoum; Peter Kuebler; Jonas J. Heymann; Megan E. Sheehy; Gabriel M. Ortiz; Graham S. Ogg; Jason D. Barbour; Jack Lenz; Alan D. Steinfeld; Douglas F. Nixon
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Proteomic studies support the use of multi-product immunoassays to monitor host cell protein impurities
Proteomics, ISSN: 16159853 16159861
Denise C. Krawitz; William F. Forrest; G. Tony Moreno; Joshua Kittleson; Kathleen M. Champion
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The crystal structure of murine coronin-1: A regulator of actin cytoskeletal dynamics in lymphocytes
Structure, ISSN: 09692126
Brent A. Appleton; Ping Wu; Wiesmann
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Cytokines, NF-kappaB, microenvironment, intestinal inflammation and cancer.
Cancer treatment and research, ISSN: 09273042
Arndt J Schottelius; Harald Dinter
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IL-27 limits IL-2 production during Th1 differentiation
Journal of Immunology, ISSN: 00221767
Alejandro V. Villarino; Jason S. Stumhofer; Christiaan J. M. Saris; Robert A. Kastelein; Frederic J. De Sauvage; Christopher A. Hunter
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Discovery of thrombin activatable fibrinolysis inhibitor (TAFI)
Journal of Thrombosis and Haemostasis, ISSN: 15387836 15387933
Bertina; Van Tilburg; Haverkate; Bouma; Von Dem Borne; Meijers; William Campbell; Dan L. Eaton; Dirk F. Hendriks; Willemse
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Interleukin-27R (WSX-1/T-cell cytokine receptor) gene-deficient mice display enhanced resistance to Leishmania donovani infection but develop severe liver immunopathology
American Journal of Pathology, ISSN: 00029440
Lucia E. Rosas; Anjali A. Satoskar; Kimberly M. Roth; Tracy L. Keiser; Joseph Barbi; Christopher A. Hunter; Frederic J. De Sauvage; Abhay R. Satoskar
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Large-scale trends in the evolution of gene structures within 11 animal genomes
PLoS Computational Biology, ISSN: 15537358 1553734X
Mark Yandell; Chris J. Mungall; Chris Smith; Simon Prochnik; Joshua S. Kaminker; George Hartzell; Suzanna E. Lewis; Gerald M. Rubin
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Counterpoint: Why biogenerics are a strawman
Nature Biotechnology, ISSN: 15461696 10870156
Robert L. Garnick
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TGF-β regulates the mechanical properties and composition of bone matrix
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Guive Balooch; Mehdi Balooch; Ravi K. Nalla; Stephen Schilling; Ellen H. Filvaroff; Grayson W. Marshall; Sally J. Marshall; Robert O. Ritchie; Rik Derynck; Tamara Alliston
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Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Michelle A. Lowes; Francesca Chamian; Maria V. Abello; Judilyn Fuentes-Duculan; Shao-Lee Lin; Rachel Nussbaum; Inna Novitskaya; Henrietta Carbonaro; Irma Cardinale; Toyoko Kikuchi; Patricia Gilleaudeau; Mary Sullivan-Whalen; Knut Wittkowski; Kim Papp; Marvin Garovoy; Wolfgang Dummer; Ralph M. Steinman; James G. Krueger
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Identification of the minimal protein domain required for priming activity of munc13-1
Current Biology, ISSN: 09609822
David R. Stevens; Zheng-Xing Wu; Ulf Matti; Harald Junge; Claudia Schirra; Ute Becherer; Sonja M. Wojcik; Nils Brose; Jens Rettig
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Angiogenesis as a therapeutic target
Nature, ISSN: 00280836 14764679
Napoleone Ferrara; Robert S. Kerbel
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Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
Clinical Cancer Research, ISSN: 10780432
Robert Yauch; Thomas Januario; Eberhard; Guy Cavet; Wenjing Zhu; Ling Fu; Thinh Q. Pham; Robert Soriano; Stinson; Somasekar Seshagiri; Zora Modrusan; Chin-Yu Lin; Vincent O'Neill; Lukas Amler
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MORT1/FADD is involved in liver regeneration
World Journal of Gastroenterology, ISSN: 10079327
Marcus Schuchmann; Felix Rückert; Jose F. Garcia-Lazaro; Andrea Karg; Jürgen Burg; Natalia Knorr; Jürgen Siebler; Eugene Varfolomeev; David Wallach; Wolfgang Schreiber; Ansgar W. Lohse; Peter R. Galle
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Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Cary D. Austin; Xiaohui Wen; Lewis Gazzard; Nelson; Richard H. Scheller; Suzie J. Scales
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Interspecies exchange mutagenesis of the first epidermal growth factor-like domain of human factor VII
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Williamson; Pyke; Sampath Sridhara; Robert F. Kelley; Morris A. Blajchman; Bryan J. Clarke
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Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Eugene Varfolomeev; Heather Maecker; Darcie Sharp; David Lawrence; Renz; Domagoj Vucic; Avi Ashkenazi
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P63 is an essential proapoptotic protein during neural development
Neuron, ISSN: 08966273
W. Bradley Jacobs; Gregory Govoni; Daniel Ho; Jasvinder K. Atwal; Fanie Barnabe-Heider; William M. Keyes; Alea A. Mills; Freda D. Miller; David R. Kaplan
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A smooth operator for LPS responses
Nature Immunology, ISSN: 15292908 15292916
Godowski
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TWEAK attenuates the transition from innate to adaptive immunity
Cell, ISSN: 00928674
Heather Maecker; Eugene Varfolomeev; Frank C. Kischkel; David Lawrence; Heidi LeBlanc; Wyne P. Lee; Stephen D. Hurst; Dimitry Danilenko; Jun Li; Ellen H. Filvaroff; Becky Yang; Dylan Daniel; Avi Ashkenazi
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Salutary effects of combining early very low-dose systemic estradiol with growth hormone therapy in girls with Turner syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Rosenfield; Nancy Devine; Joanne Julius Hunold; Nelly Mauras; Thomas Moshang Jr.; Allen W. Root
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Analysis of protein therapeutics by capillary electrophoresis: Applications and challenges
Developments in Biologicals, ISSN: 14246074
Stacey Ma
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Quantitative structure-activity relationships of methotrexate and methotrexate analogues transported by the rat multispecific resistance- associated protein 2 (rMrp2)
European Journal of Pharmaceutical Sciences, ISSN: 09280987
Chee Ng; Yun-De Xiao; Bert L. Lum; Yong-Hae Han
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Expression of HIF-1α in human tumours [5]
Journal of Clinical Pathology, ISSN: 00219746
Adrian M. Jubb; Kenneth J. Hillan
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Rituximab in combination with fludarabine chemotherapy in low-grade or follicular lymphoma
Journal of Clinical Oncology, ISSN: 0732183X
Myron S. Czuczman; Koryzna; Mohr; Stewart; Donohue; Blumenson; Bernstein; McCarthy; Alam; Hernandez-Ilizaliturri; Skipper; Brown; Chanan-Khan; Klippenstein; Loud; Mike K Rock; Benyunes; Grillo-Lopez; Bernstein
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Development and the boundaries of the firm: A knowledge-based examination in drug development
Academy of Management 2005 Annual Meeting: A New Vision of Management in the 21st Century, AOM 2005,
Jeffrey T. Macher; Christopher S. Boerner
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Targeted therapy: Wave of the future
Journal of Clinical Oncology, ISSN: 0732183X
Pegram; Pietras; Alex Bajamonde; Pam Klein; Gwendolyn Fyfe
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Requirement for the SnoN oncoprotein in transforming growth factor β-induced oncogenic transformation of fibroblast cells
Molecular and Cellular Biology, ISSN: 02707306
Qingwei Zhu; Sonia Pearson-White; Kunxin Luo
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Class I FIPs, Rab11-binding proteins that regulate endocytic sorting and recycling
Methods in Enzymology, ISSN: 00766879
Elizabeth Tarbutton; Andrew A. Peden; Jagath R. Junutula; Rytis Prekeris
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Agreement in histologic assessments of the pituitary pars intermedia in aged horses
American Journal of Veterinary Research, ISSN: 00029645
Dianne McFarlane; Lisa M. Miller; Linden E. Craig; Noel Dybdal; Perry L. Habecker; Margaret A. Miller; Jon S. Patterson; Alastair E. Cribb
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Heterogeneity of recombinant antibodies: Linking structure to function
Developments in Biologicals, ISSN: 14246074
Reed J. Harris
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Isolation and culture of hair cell progenitors from postnatal rat cochleae
Journal of Neurobiology, ISSN: 00223034
Suo-qiang Zhai; Li Shi; Bu-Er Wang; Gui-liang Zheng; Wei Song; Yin-yan Hu; Gao
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Proteomics
Methods in Enzymology, ISSN: 00766879
Stults; David Arnott
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Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Andrew R. Hoffman; Beverly M. K. Biller; David Cook; Joyce Baptista; Bernard L. Silverman; Dao; Kenneth M. Attie; Fielder; Thomas J. Maneatis; Barbara M. Lippe
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Impaired skin barrier function in dermatologic disease and repair with moisturization
Cutis, ISSN: 00114162
Mark Lebwohl; Lisa G. Herrmann
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Strategies for developing a successful electronic submission
American Pharmaceutical Review, ISSN: 10998012
Pawson
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Clinical efficacy of efalizumab in patients with chronic plaque psoriasis: Results from three randomized placebo-controlled phase III trials: Part I
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
David M. Pariser; Kenneth B. Gordon; Kim Papp; Craig Leonardi; Paul Kwon; Peter Compton; Amy Chen Rundle; Patricia Walicke; Mark Lebwohl
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Safety of efalizumab in patients with moderate to severe chronic plaque psoriasis: Review of clinical data. Part II
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Kim Papp; Charles Camisa; Stephen P. Stone; Ivor Caro; Xiaolin Wang; Peter Compton; Patricia Walicke; Alice Gottlieb
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Symptom control and improved functioning: The effect of omalizumab on Asthma-Related Quality of Life (ARQL)
Journal of Asthma, ISSN: 02770903 15324303
Allan T. Luskin; Mark Kosinski; Bresnahan; Ashby; Dennis A. Wong
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Minimally important differences were estimated for the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) instrument using a combination of distribution- and anchor-based approaches
Journal of Clinical Epidemiology, ISSN: 08954356
Yost; Cella; Chawla; Holmgren; Eton; Ayanian; West
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