Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12201 - 12250 OF 15723 RESULTS

July 30, 1999

Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors

Science, ISSN: 00368075

Hans D. Brightbill; Daniel H. Libraty; Stephan R. Krutzik; Ruey-Bing Yang; John T. Belisle; Joshua R. Bleharski; Michael Maitland; Michael V. Norgard; Scott E. Plevy; Stephen T. Smale; Patrick J. Brennan; Bloom; Godowski; Robert L. Modlin

July 30, 1999

Cell activation and apoptosis by bacterial lipoproteins through Toll- like receptor-2

Science, ISSN: 00368075

Antonios O. Aliprantis; Ruey-Bing Yang; Melanie R Mark; Shelly Suggett; Devaux; Justin D. Radolf; Gary R. Klimpel; Godowski; Arturo Zychlinsky

July 30, 1999

Multiple Ras effector pathways contribute to G1 cell cycle progression

Journal of Biological Chemistry, ISSN: 00219258

Hendrik Gille; Julian Downward

July 22, 1999

A convenient microscale colorimetric method for terminal galactose on immunoglobulins

Biochemical and Biophysical Research Communications, ISSN: 0006291X

T. Shantha Raju; Namita Nayak; Briggs; O'Connor; Laura Lerner

July 21, 1999

Hemostatic effects of 1 mg daily warfarin on post CABG patients

Journal of Thrombosis and Thrombolysis, ISSN: 09295305

Jeanine M. Walenga; Debra Hoppensteadt; Roque Pifarré; Michael D. Cressman; Donald B. Hunninghake; Fox; Michael L. Terrin; Jeffrey L. Probstfield

July 20, 1999

Stoichiometry of the interaction between the major histocompatibility- complex-related Fc receptor and its Fc ligand

Biochemistry, ISSN: 00062960

Luis M. Sánchez; David M. Penny; Pamela J. Bjorkman

July 20, 1999

Transgene expression in the guinea pig cochlea mediated by a lentivirus- derived gene transfer vector

Human Gene Therapy, ISSN: 10430342

Jay J. Han; Anand N. Mhatre; Michael Wareing; Robert Pettis; Gao; Romain N. Zufferey; Didier Trono; Anil K. Lalwani

July 16, 1999

Real-time control of antibody loading during protein A affinity chromatography using an on-line assay

Journal of Chromatography A, ISSN: 00219673

Fahrner; Gregory S. Blank

July 15, 1999

The mechanism of activation of NADPH oxidase in the cell-free system: The activation process is primarily catalytic and not through the formation of a stoichiometric complex

Biochemical Journal, ISSN: 02646021

Andrew R. Cross; Erickson; John T. Curnutte

July 15, 1999

Signaling events induced by lipopolysaccharide-activated Toll-like receptor 2

Journal of Immunology, ISSN: 00221767

Ruey-Bing Yang; Melanie R Mark; Austin L. Gurney; Godowski

July 15, 1999

Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior

Journal of Neuroscience, ISSN: 02706474

Ruey-Bing Yang; Susan W. Robinson; Wei-Hong Xiong; King-Wai Yau; David G. Birch; Garbers

July 15, 1999

Determination of residues involved in ligand binding and signal transmission in the human IFN-α receptor 2

Journal of Immunology, ISSN: 00221767

Anan Chuntharapai; Gibbs; Lu; Ow; Scot A. Marsters; Avi Ashkenazi; De Vos; K.Jin Kim

July 12, 1999

Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane

Journal of Cell Biology, ISSN: 00219525

Antonius Koller; William B. Snyder; Klaas Nico Faber; Thibaut J. Wenzel; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani

July 8, 1999

Predictors and timing of adverse experiences during transdermal nicotine therapy

Drug Safety, ISSN: 01145916

Steven G. Gourlay; Andrew Forbes; Tracey Marriner; John J. McNeil

July 2, 1999

Identification of amino acids that modulate mannose phosphorylation of mouse DNase I, a secretory glycoprotein

Journal of Biological Chemistry, ISSN: 00219258

Atsushi Nishikawa; Akash Nanda; Walter Gregory; John Frenz; Stuart Kornfeld

July 2, 1999

Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC

Journal of Molecular Biology, ISSN: 00222836

Ultsch; Wiesmann; Laura C. Simmons; Jill Henrich; Yang; Dorothea Reilly; Bass; De Vos

July 1, 1999

High-performance tangential flow filtration using charged membranes

Journal of Membrane Science, ISSN: 03767388

Robert Van Reis; Brake; Charkoudian; Burns; Andrew Zydney

June 30, 1999

Investigation of protein-surfactant interactions by analytical ultracentrifugation and electron paramagnetic resonance: The use of recombinant human tissue factor as an example

Pharmaceutical Research, ISSN: 07248741

LaToya S. Jones; Cipolla; Jun Liu; Steven J. Shire; Theodore W. Randolph

June 15, 1999

Cardiotrophin-1 attenuates endotoxin-induced acute lung injury

Journal of Surgical Research, ISSN: 00224804

Edward J. Pulido; Brian D. Shames; Diane Pennica; O'Leary; Denis D. Bensard; Brian S. Cain; Robert C. McIntyre Jr.

June 15, 1999

Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord

Journal of Neuroscience, ISSN: 02706474

Kerr; Bradbury; David L. H. Bennett; Trivedi; Dassan; French; David L. Shelton; McMahon; Stephen W.N. Thompson

June 15, 1999

Zebrafish genetic map with 2000 microsatellite markers

Genomics, ISSN: 08887543

Nobuyoshi Shimoda; Ela W. Knapik; John Ziniti; Chäng Sim; Erika Yamada; Stacy Kaplan; Donald Jackson; Frederic J. De Sauvage; Howard Jacob; Mark C. Fishman

June 11, 1999

RIP3, a novel apoptosis-inducing kinase

Journal of Biological Chemistry, ISSN: 00219258

Xiaoqing Sun; Lee James; Tony A. Navas; Daryl T. Baldwin; Stewart; Vishva M. Dixit

June 10, 1999

The toll of innate immunity on microbial pathogens

New England Journal of Medicine, ISSN: 00284793

Robert L. Modlin; Hans D. Brightbill; Godowski

June 5, 1999

Lack of developmental neurotoxicity of MN rgp120/HIV-1 administered subcutaneously to neonatal rats

Toxicological Sciences, ISSN: 10966080

Bussiere; Laurel M. Hardy; Peterson; John A. Foss; Robert H. Garman; Alan M. Hoberman; Mildred S. Christian

June 1, 1999

A low-volume, short-path length dynamic light scattering sample cell for highly turbid suspensions

Analytical Biochemistry, ISSN: 00032697

Thomas W. Patapoff; Travis H. Tani; Cromwell

June 1, 1999

The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII

Biochemistry, ISSN: 00062960

Yung-Hsiang Kao; Geoffrey F. Lee; Yang Wang; Melissa A. Starovasnik; Robert F. Kelley; Spellman; Laura Lerner

June 1, 1999

Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system

Development (Cambridge), ISSN: 09501991

Stavros Taraviras; Camelia V. Marcos-Gutierrez; Pascale Durbec; Harsha Jani; Maria Grigoriou; Madhu Sukumaran; Li-Chong Wang; Mary Hynes; Geoffrey Raisman; Vassilis Pachnis

June 1, 1999

Identification of a human anti-CD55 single-chain Fv by subtractive panning of a phage library using tumor and nontumor cell lines

Cancer Research, ISSN: 00085472

John B.B. Ridgway; Eric Ng; Jeffrey Kern; James Lee; Brush; Goddard; Paul J. Carter

June 1, 1999

A dynamic film model for ultrafiltration

Journal of Membrane Science, ISSN: 03767388

Perkins; Saksena; Van Reis

June 1, 1999

VEGF couples hypertrophic cartilage remodeling, ossification and angiogenesis during endochondral bone formation

Nature Medicine, ISSN: 10788956

Hans-Peter Gerber; Thiennu H. Vu; Anne Ryan; Joe Kowalski; Zena Werb; Napoleone Ferrara

June 1, 1999

The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII

Biochemistry, ISSN: 00062960

Kao; Geoffrey F. Lee; Yang Wang; Melissa A. Starovasnik; Robert F. Kelley; Spellman; Laura Lerner

May 28, 1999

UC-genentech trial [1] (multiple letters)

Science, ISSN: 00368075

Henner; David V. Goeddel; Herbert Heyneker; Itakura Keiichi; Yansura; Ross; Miozzari; Peter H. Seeburg

May 28, 1999

Simultaneous presence of p47(phox) and flavocytochrome b-245 are required for the activation of NADPH oxidase by anionic amphiphiles: Evidence for an intermediate state of oxidase activation

Journal of Biological Chemistry, ISSN: 00219258

Andrew R. Cross; Erickson; John T. Curnutte

May 27, 1999

Genentech stands by original data [3]

Nature, ISSN: 00280836

Henner; David V. Goeddel; Herbert Heyneker; Itakura Keiichi; Yansura; Ross; Miozzari

May 22, 1999

A two-dimensional protein map of Chinese hamster ovary cells

Electrophoresis, ISSN: 01730835

Kathleen M. Champion; David Arnott; William J. Henzel; Sam Hermes; Weikert; Stults; Vanderlaan; Lynne Krummen

May 19, 1999

Structural basis for the binding specificity of a SSTR1-Selective analog of somatostatin

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Longchuan Chen; Carl Hoeger; Jean Rivier; V. Danial Fitzpatrick; Richard L. Vandlen; Armen H. Tashjian Jr.

May 18, 1999

Total alanine-scanning mutagenesis of insulin-like growth factor I (IGF- I) identifies differential binding epitopes for IGFBP-1 and IGFBP-3

Biochemistry, ISSN: 00062960

Yves Dubaquié; Henry B. Lowman

May 17, 1999

Cultivation of Tetrahymena thermophila in a 1.5-m3 airlift bioreactor

Applied Microbiology and Biotechnology, ISSN: 01757598

Hellenbroich; Ulrich Valley; Thomas Ryll; Roland Wagner; Tekkanat; Kessler; Roß; Deckwer

May 17, 1999

Performance of sonication and microfluidization for liquid-liquid emulsification

Pharmaceutical Development and Technology, ISSN: 10837450

Maa; Chung C. Hsu

May 17, 1999

Insulin-like growth factor I regulates renal development in rodents

Developmental Genetics, ISSN: 0192253X

Sharon A. Rogers; Powell-Braxton; Marc R. Hammerman

May 15, 1999

Development and validation of real-time quantitative reverse transcriptase-polymerase chain reaction for monitoring gene expression in cardiac myocytes in vitro

Analytical Biochemistry, ISSN: 00032697

Jane Winer; Chris Jung; Irene Shackel; P. Mickey Williams

May 15, 1999

TRAIL (Apo-2L) and TRAIL receptors in human placentas: Implications for immune privilege

Journal of Immunology, ISSN: 00221767

Teresa A. Phillips; Jian Ni; Pan; Steven M. Ruben; Ying-Fei Wei; Judith L. Pace; Joan S. Hunt

May 14, 1999

Purification and quantitation of tumor necrosis factor receptor immunoadhesin using a combination of immunoaffinity and reversed-phase chromatography

Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 13872273

John E. Battersby; Vanderlaan; Andrew J.S. Jones

May 1, 1999

Platelet glycoprotein IIb/IIIa inhibition by Lamifiban reduces the neointimal response to angioplasty in a porcine model

Heart, ISSN: 13556037

Chico; Gunn; Arnold; Sherron L. Bullens; Bunting; Cumberland; Crossman

May 1, 1999

Sensitization of AIDS-Kaposi's sarcoma cells to Apo-2 ligand-induced apoptosis by actinomycin D

Journal of Immunology, ISSN: 00221767

Shunsuke Mori; Kaoru Murakami-Mori; Shuji Nakamura; Avi Ashkenazi; Benjamin Bonavida

May 1, 1999

Down-regulation of human basophil IgE and FCεRIα surface densities and mediator release by anti-IgE-infusions is reversible in vitro and in vivo

Journal of Immunology, ISSN: 00221767

Sarbjit S. Saini; Donald W. Macglashan Jr.; Sherry A. Sterbinsky; Alkis Togias; Daniel C. Adelman; Lawrence M. Lichtenstein; Bruce S. Bochner

May 1, 1999

Kinase receptor activation (KIRA): A rapid and accurate alternative to end-point bioassays

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Michael D Sadick; Anthony Intintoli; Quarmby; April McCoy; Eleanor Canova-Davis; Victor Ling

May 1, 1999

Purification of CMP-N-acetylneuraminic acid synthetase from bovine anterior pituitary glands

Glycobiology, ISSN: 09596658

Justine Vionnet; Nelydia Conception; Warner; Gerardo Zapata; John Hanover; Williie F. Vann

April 29, 1999

Aberrant metabolic sialylation of recombinant proteins expressed in Chinese hamster ovary cells in high productivity cultures

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Santell; Thomas Ryll; Etcheverry; Michael Santoris; George Dutina; Angie Wang; Jane Gunson; Warner

April 26, 1999

Real-time monitoring of recombinant antibody breakthrough during protein a affinity chromatography

Biotechnology and Applied Biochemistry, ISSN: 08854513

Fahrner; Gregory S. Blank

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