Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 16396 RESULTS

February 17, 1999

Effects of chronic renal failure and growth hormone on serum levels of insulin-like growth factor-binding protein-4 (IGFBP-4) and IGFBP-5 in children: A report of the southwest pediatric nephrology study group

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

David R. Powell; Susan K. Durham; Eileen D. Brewer; James W. Frane; Sandra L. Watkins; Ronald J. Hogg; Subburaman Mohan

February 15, 1999

Spontaneous activation of NADPH oxidase in a cell-free system: Unexpected multiple effects of magnesium ion concentrations

Biochemical Journal, ISSN: 02646021

Andrew R. Cross; Erickson; Beverly A. Ellis; John T. Curnutte

February 15, 1999

Structure of a CXC chemokine-receptor fragment in complex with interleukin-8

Structure, ISSN: 09692126

Nicholas J. Skelton; Quan; Dorothea Reilly; Henry B. Lowman

February 2, 1999

Recombinant human Dnase I (rhDNase) in patients with lupus nephritis

Lupus, ISSN: 09612033

John C. Davis; Manzi; Yarboro; Rairie; McInnes; Averthelyi; Sinicropi; Victoria Hale; Balow; Austin; Boumpas; Klippel

February 1, 1999

Protein identification using 20-minute Edman cycles and sequence mixture analysis

Analytical Biochemistry, ISSN: 00032697

William J. Henzel; Jake Tropea; David Dupont

February 1, 1999

Incorporation of 15N from ammonium into the N-linked oligosaccharides of an immunoadhesin glycoprotein expressed in Chinese hamster ovary cells

Glycobiology, ISSN: 09596658

Martin Gawlitzek; Damon I. Papac; Mary B. Sliwkowski; Thomas Ryll

February 1, 1999

Specification of dopaminergic and serotonergic neurons in the vertebrate CNS

Current Opinion in Neurobiology, ISSN: 09594388

Mary Hynes; Rosenthal

February 1, 1999

The domains of death: Evolution of the apoptosis machinery

Trends in Biochemical Sciences, ISSN: 09680004

Aravind; Vishva M. Dixit; Eugene V. Koonin

February 1, 1999

Analysing hippocampal function in transgenic mice: An ethological perspective

Trends in Neurosciences, ISSN: 01662236

Gerlai; Nicola S. Clayton

January 29, 1999

UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells

FEBS Letters, ISSN: 00145793

Mao; Yu; Zhong; Wenlu Li; Brush; Steve Sherwood; Adams; Pan

January 28, 1999

Sonic hedgehog signaling by the patched-smoothened receptor complex

Current Biology, ISSN: 09609822

Maximilien Murone; Rosenthal; Frederic J. De Sauvage

January 26, 1999

Factor VIIa's first epidermal growth factor-like domain's role in catalytic activity

Biochemistry, ISSN: 00062960

Jianping Jin; Jinli Chang; Jen-Yea Chang; Robert F. Kelley; Darrel W. Stafford; David L. Straight

January 22, 1999

Developmental expression and co-localization of cyclin G1 and the B' subunits of protein phosphatase 2a in neurons

Molecular Brain Research, ISSN: 0169328X

Menno Van Lookeren Campagne; Koji Okamoto; Carol Prives; Ramanjit Gill

January 22, 1999

Trophic effects of cardiotrophin-1 and interleukin-11 on rat dorsal root ganglion neurons in vitro

Molecular Brain Research, ISSN: 0169328X

Michael Thier; Mark Hall; John K. Heath; Diane Pennica; Joachim Weis

January 20, 1999

A simple, two-component buffer enhances use of chromatofocusing for processing of therapeutic proteins

Biotechnology and Bioengineering, ISSN: 00063592

Kathleen A. Logan; Inger Lagerlund; Steven M. Chamow

January 19, 1999

Oncogenic ras fails to restore an in vivo tumorigenic phenotype in embryonic stem cells lacking vascular endothelial growth factor (VEGF)

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Yu-Ping Shi; Napoleone Ferrara

January 19, 1999

Permissive role of thrombopoietin and granulocyte colony-stimulating factor receptors in hematopoietic cell fate decisions in vivo

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Ruedi Stoffel; Sandra Ziegler; Nico Ghilardi; Birgit Ledermann; Frederic J. De Sauvage; Radek C. Skoda

January 19, 1999

Involvement of regulatory and catalytic subunits of phosphoinositide 3-kinase in NF-κB activation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Christophe Béraud; William J. Henzel; Patrick A. Baeuerle

January 11, 1999

Molecular analysis of chronic granulomatous disease caused by defects in gp91-phox

Human Mutation, ISSN: 10597794

Pablo Patino; Juan E. Perez; Juan A. Lopez; Antonio Condino-Neto; Anete S. Grumach; Jorge H. Botero; John T. Curnutte; Diana García De Olarte

January 8, 1999

A discrete three-amino acid segment (LVI) at the C-terminal end of kinase-impaired ErbB3 is required for transactivation of ErbB2

Journal of Biological Chemistry, ISSN: 00219258

Gabriele Schaefer; Robert W. Akita; Mark X. Sliwkowski

January 8, 1999

Non-flammable preparative reversed-phase liquid chromatography of recombinant human insulin-like growth factor-I

Journal of Chromatography A, ISSN: 00219673

Fahrner; Philip M. Lester; Gregory S. Blank; David H. Reifsnyder

January 5, 1999

Effect of electric field on liquid chromatographic separation of peptide digests. Combining capillary separation techniques

Journal of Chromatography A, ISSN: 00219673

Alex Apffel; Hongfeng Yin; William S. Hancock; Douglass McManigill; John Frenz; Shiaw-Lin Wu

January 5, 1999

Treatment with growth hormone enhances contractile reserve and intracellular calcium transients in myocytes from rats with postinfarction heart failure

Circulation, ISSN: 00097322

Minori Tajima; Ellen O. Weinberg; Jozef Bartunek; Hongkui Jin; Renhui Yang; Nicholas F. Paoni; Beverly H. Lorell

January 5, 1999

Use of the steric mass action model in ion-exchange chromatographic process development

Journal of Chromatography A, ISSN: 00219673

Harish V. Iyer; Sarah Tapper; Philip M. Lester; Bradley Wolk; Robert Van Reis

January 4, 1999

Boo, a novel negative regulator of cell death, interacts with Apaf-1

EMBO Journal, ISSN: 02614189

Qizhong Song; Yongping Kuang; Vishva M. Dixit; Claudius Vincenz

January 1, 1999

Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease

Liver, ISSN: 01069543

Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Sherman Fong

January 1, 1999

Intraocular pharmacokinetics and safety of a humanized monoclonal antibody in rabbits after intravitreal administration of a solution or a PLGA microsphere formulation

Toxicological Sciences, ISSN: 10966080

Joyce Mordenti; Karen Thomsen; Vojtech Licko; Lea Berleau; Jeanne Kahn; R. Andrew Cuthbertson; Duenas; Anne Ryan; Cheryl A. Schofield; Terrence W. Berger; Meng; Cleland

January 1, 1999

Comparisons of the Intraocular Tissue Distribution, Pharmacokinetics, and Safety of 125I-Labeled Full-Length and Fab Antibodies in Rhesus Monkeys Following Intravitreal Administration

Toxicologic Pathology, ISSN: 01926233

Joyce Mordenti; R. Andrew Cuthbertson; Napoleone Ferrara; Karen Thomsen; Lea Berleau; Vojtech Licko; Philip C. Allen; Celia R. Valverde; Meng; David T.W. Fei; Kathleen M. Fourre; Anne Ryan

January 1, 1999

Hypertension and endothelial dysfunction in apolipoprotein E knockout mice

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Renhui Yang; Powell-Braxton; Annie Ko Ogaoawara; Noel Dybdal; Bunting; Osamu Ohneda; Hongkui Jin

January 1, 1999

A common mechanism for recombinant human NGF, BDNF, NT-3, and murine NGF slow unfolding

Protein Science, ISSN: 09618368

Linda R. De Young; Charles H. Schmelzer; Louis E. Burton

January 1, 1999

Airway epithelial CFTR mRNA expression in cystic fibrosis patients after repetitive administration of a recombinant adenovirus

Journal of Clinical Investigation, ISSN: 00219738

Ben-Gary Harvey; Philip L. Leopold; Neil R. Hackett; Tina M. Grasso; P. Mickey Williams; Ayly Ling Tucker; Robert J. Kaner; Barbara Ferris; Gonda; Sweeney; Ramachandran Ramalingam; Kovesdi; Steven Shak; Crystal

January 1, 1999

Creatine: a review of efficacy and safety.

Journal of the American Pharmaceutical Association (Washington,D.C. : 1996), ISSN: 10865802

Graham; Hatton

January 1, 1999

Development of noradrenergic neurons in the zebrafish hindbrain requires BMP, FGF8, and the homeodomain protein soulless/Phox2a

Neuron, ISSN: 08966273

Guo; Brush; Hiroki Teraoka; Goddard; Stephen W. Wilson; Mary C. Mullins; Rosenthal

January 1, 1999

Conformational changes in the activation loop of the insulin receptor's kinase domain

Protein Science, ISSN: 09618368

Mark Frankel; Steven M. Bishop; Ararat J. Ablooglu; Yuan-Ping Han; Ronald A. Kohanski

January 1, 1999

Chromatography of recombinant proteins.

Developments in biological standardization, ISSN: 03015149

O'Connor

January 1, 1999

Kinase Receptor Activation (KIRA): a rapid and accurate alternative to endpoint bioassays.

Developments in biological standardization, ISSN: 03015149

Michael D Sadick

January 1, 1999

How much insulin-like growth factor-I (IGF-I) circulates?: impact of standardization on IGF-I assay accuracy.

Developments in biological standardization, ISSN: 03015149

Quarmby; Quan

January 1, 1999

Pharmacokinetics of insulin-like growth factor I in hypopituitarism: Correlation with binding proteins

American Journal of Physiology - Endocrinology and Metabolism, ISSN: 01931849

Nelly Mauras; Quarmby; Duane C. Bloedow

January 1, 1999

Role of baseline parameters in determining indirect pharmacodynamic responses

Journal of Pharmaceutical Sciences, ISSN: 00223549

Sun; William J. Jusko

January 1, 1999

FGF-19, a novel fibroblast growth factor with unique specificity for FGFR4

Cytokine, ISSN: 10434666

Xie; Ilona N. Holcomb; Bethanne Deuel; Patrick Dowd; Arthur Huang; Alicia Vagts; Foster; Jie Liang; Brush; Qimin Gu; Kenneth J. Hillan; Goddard; Austin L. Gurney

January 1, 1999

Allergic bronchopulmonary aspergillosis in cystic fibrosis: Reported prevalence, regional distribution, and patient characteristics

Chest, ISSN: 00123692

David E. Geller; Kaplowitz; Michael Light; Andrew A. Colin

January 1, 1999

A human antibody that binds to the γ-carboxyglutamic acid domain of factor IX is a potent antithrombotic in vivo

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Jacques Himber; Louis Burcklen; Paul Moran; Peek; Shelley Suggett; Devaux; Daniel Kirchhofer

January 1, 1999

Role of vascular endothelial growth factor in the regulation of angiogenesis

Kidney International, ISSN: 00852538

Napoleone Ferrara

January 1, 1999

A real time quantitative PCR-based method for the detection and quantification of simian virus 40

Biologicals, ISSN: 10451056

Shi; Jeniffer Ho; Lenore A Norling; Margaret Roy; Yuan Xu

January 1, 1999

Real time quantitative PCR as a method to evaluate simian virus 40 removal during pharmaceutical protein purification

Biologicals, ISSN: 10451056

Shi; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Alison J. Laney; Yuan Xu

January 1, 1999

Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels

American Journal of Pathology, ISSN: 00029440

Suya Yang; Jennifer Graham; Jeanne Kahn; Eric A. Schwartz; Mary E. Gerritsen

January 1, 1999

The biology of human epidermal growth factor receptor 2.

Current Oncology Reports, ISSN: 15233790

Sundaresan; Elicia M. Penuel; Mark X. Sliwkowski

January 1, 1999

Development and testing of a thermoluminescence dosemeter for mixed neutron-photon-beta radiation fields

Radiation Protection Dosimetry, ISSN: 01448420

Zummo; Liu

January 1, 1999

Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection

Journal of Virology, ISSN: 0022538X

Tsutomu Murakami; Tian-Yuan Zhang; Yoshio Koyanagi; Yuetsu Tanaka; Jin Kim; Yoichi Suzuki; Shigeru Minoguchi; Hirokazu Tamamura; Michinori Waki; Akiyoshi Matsumoto; Nobutaka Fujii; Hisatoshi Shida; James A. Hoxie; Stephen C. Peiper; Naoki Yamamoto

January 1, 1999

Commentary: Role of the pathologist in the identification and characterization of therapeutic molecules

Toxicologic Pathology, ISSN: 01926233

Anne Ryan

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.