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Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13051 - 13100 OF 16396 RESULTS

Growth hormone binding affinity for its receptor surpasses the requirements for cellular activity
Biochemistry, ISSN: 00062960
Kenneth H. Pearce Jr.; Cunningham; Fuh; Tuula Teeri; James A. Wells
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A cardioactive peptide from the southern armyworm, Spodoptera eridania
Peptides, ISSN: 01969781
Kenji Furuya; Murray Hackett; Marc A. Cirelli; Kathleen M. Schegg; Houle Wang; Jeffrey Shabanowitz; Donald F. Hunt; David A. Schooley
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The yeast a1 and α2 homeodomain proteins do not contribute equally to heterodimeric DNA binding
Molecular and Cellular Biology, ISSN: 02707306
Yisheng Jin; Hualin Zhong; Andrew K. Vershon
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Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of a humanized monoclonal antibody against vascular endothelial growth factor
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Yvonne S. Lin; Cindy B. Nguyen; Jose-Luis Mendoza; Escandon; David T.W. Fei; Meng; Modi
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The optimal flow rate and column length for maximum production rate of protein A affinity chromatography
Bioprocess Engineering, ISSN: 0178515X
Fahrner; Harish V. Iyer; Gregory S. Blank
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Therapy of allergic pulmonary diseases with anti-IgE antibodies. A review
Pediatric Pulmonology, ISSN: 87556863
Robert B. Fick Jr.
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Consultation before thrombolytic therapy in acute myocardial infarction
American Journal of Cardiology, ISSN: 00029149
Nadim Al-Mubarak; William J. Rogers; Costas Lambrew; Laura J. Bowlby; William J. French
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A novel 96-well scintillation proximity assay for the measurement of apoptosis
Cytotechnology, ISSN: 09209069
Amy E. McMurtrey; Robert J. Graves; Jeff Hooley; Gerard Brophy; Gail D. Lewis Phillips
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VEGF loaded microspheres injected intramuscularly produce local neovascularization in normal, aged C57BL-6 mice
Proceedings of the Controlled Release Society, ISSN: 10220178
Daugherty; Hope Steinmetz; Hoeffel; Duenas; Tobin; Franklin V. Peale Jr.; Anne Ryan; Bunting; Cleland
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Antibody variable region binding by Staphylococcal protein A: Thermodynamic analysis and location of the Fv binding site on E-domain
Protein Science, ISSN: 09618368
Melissa A. Starovasnik; Mark P. O'Connell; Wayne J. Fairbrother; Robert F. Kelley
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Importance of VEGF for breast cancer angiogenesis in vivo: Implications from intravital microscopy of combination treatments with an anti-VEGF neutralizing monoclonal antibody and doxorubicin
Anticancer Research, ISSN: 02507005
Per Borgström; Daniel P. Gold; Kenneth J. Hillan; Napoleone Ferrara
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Vascular endothelial growth factor: Molecular and biological aspects
Current Topics in Microbiology and Immunology, ISSN: 0070217X
Napoleone Ferrara
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Reported in vivo spliced site mutations in the factor IX gene: Severity of splicing defects and a hypothesis for predicting deleterious splice donor mutations
Human Mutation, ISSN: 10597794
Rhett P. Ketterling; Joni B. Drost; William A. Scaringe; Dong-Zhou Liao; Jing-Zhong Liu; Carol K. Kasper; Steve S. Sommer
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Sialidase gene transfection enhances epidermal growth factor receptor activity in an epidermoid carcinoma cell line, A4311
Cancer Research, ISSN: 00085472
Emmanuelle J. Meuillet; Roger Kroes; Hirotaka Yamamoto; Warner; Ferrari; Barbara Mania-Farnell; David George; Abdelhadi Rebbaa; Joseph R. Moskal; Eric G. Bremer
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A survey of the recent patent literature on the delivery of genes and oligonucleotides
Journal of Drug Targeting, ISSN: 1061186X
Mrsny
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Assessment of rhVEGF integrity in a photopolymerizable hydrogel
Proceedings of the Controlled Release Society, ISSN: 10220178
Duenas; Philbrook; Roth; Cleland
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Erratum: UCP4, a novel brain-specific mitochondrial protein that reduces membrane potential in mammalian cells (FEBS Letters 443 (1999) (326-330) PII: S001457939801713X)
FEBS Letters, ISSN: 00145793
Mao; Yu; Zhong; Wenlu Li; Brush; Steve Sherwood; Adams; Pan
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Receptor binding and biological activity of mammalian expressed sensory and motor neuron-derived factor (SMDF)
Growth Factors, ISSN: 08977194
Phyllis L. Osheroff; Siao Ping Tsai; Nancy Y. Chiang; King; Li; Gail D. Lewis; Kenneth Wong; William J. Henzel; Mather
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Regulation of Apo-2 ligand/TRAIL expression in NK cells - Involvement in NK cell-mediated cytotoxicity
Cytokine, ISSN: 10434666
Ann-Charlotte Johnsen; Johan Haux; Bjørg Steinkjer; Unni Nonstad; Kjartan Egeberg; Anders Sundan; Avi Ashkenazi; Espevik
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Single-administration vaccines: Controlled-release technology to mimic repeated immunizations
Trends in Biotechnology, ISSN: 01677799
Cleland
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Use of infrared spectroscopy to assess secondary structure of human growth hormone within biodegrable microspheres
Journal of Pharmaceutical Sciences, ISSN: 00223549
Tzung-Horng Yang; Aichun Dong; Jeffrey D. Meyer; OluFunmi Johnson; Cleland; John F. Carpenter
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Thrombopoietin (Tpo) in the fetus and neonate: Tpo concentrations in preterm and term neonates, and organ distribution of Tpo and its receptor (c-mpl) during human fetal development
Early Human Development, ISSN: 03783782
Martha C. Sola; Sandra E. Juul; Meng; Shaily Garg; Paul Sims; Darlene A. Calhoun; J. Benjamin Dame; Robert D. Christensen
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Induction of apoptosis in cancer cells by tumor necrosis factor and butyrolactone, an inhibitor of cyclin-dependent kinases
Brazilian Journal of Medical and Biological Research, ISSN: 1414431X 0100879X
Belizário; Steve Sherwood; Beçak
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Role of baseline parameters in determining indirect pharmacodynamic responses
Journal of Pharmaceutical Sciences, ISSN: 00223549
Yu-Nien Sun; William J. Jusko
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Expression of the mucosal vascular addressin, MAdCAM-1, in inflammatory liver disease
Liver, ISSN: 01069543
Kenneth J. Hillan; Kelly E. Hagler; Roderick N. M. MacSween; Anne Ryan; Renz; Chiu; Rod K. Ferrier; George L. Bird; Amar P. Dhillon; Linda D. Ferrell; Fong
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Evidence of anaphylaxy after alteplase infusion
Stroke, ISSN: 00392499
Jobst Rudolf; Martin Grond; Prince; Susanne Schmülling; Wolf-Dieter Heiss
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Pex17p is required for import of both peroxisome membrane and lumenal proteins and interacts with Pex19p and the peroxisome targeting signal- receptor docking complex in Pichia pastoris
Molecular Biology of the Cell, ISSN: 10591524
William B. Snyder; Antonius Koller; Aaron Jobu Choy; Monique A. Johnson; James M. Cregg; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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Pex19p interacts with Pex3p and Pex10p and is essential for peroxisome biogenesis in Pichia pastoris
Molecular Biology of the Cell, ISSN: 10591524
William B. Snyder; Klaas Nico Faber; Thibaut J. Wenzel; Antonius Koller; Georg H. Lüers; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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Elastase substrate specificity tailored through substrate-assisted catalysis and phage display
Protein Engineering, ISSN: 02692139
William Dall'Acqua; Cornelia Halin; Maria L. Rodrigues; Paul J. Carter
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Somatotroph and lactotroph changes in the adenohypophyses of mice with disrupted insulin-like growth factor I gene
Endocrinology, ISSN: 00137227
Lucia Stefaneanu; Powell-Braxton; Wesley B. Won; Varadaraj Chandrashekar; Andrzej Bartke
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Analytical ultracentrifugation in the pharmaceutical industry
Journal of Pharmaceutical Sciences, ISSN: 00223549
Jun Liu; Steven J. Shire
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Selective cloning of cell surface proteins involved in organ development: Epithelial glycoprotein is involved in normal epithelial differentiation
Endocrinology, ISSN: 00137227
Jean-Philippe Stephan; Penelope E. Roberts; Bald; James Lee; Qimin Gu; Devaux; Mather
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Effects of Igf1 gene deletion on postnatal growth patterns
Endocrinology, ISSN: 00137227
Jie Wang; Jian Zhou; Powell-Braxton; Carolyn Bondy
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Evidence that insulin-like growth factor I and growth hormone are required for prostate gland development
Endocrinology, ISSN: 00137227
Weifeng Ruan; Powell-Braxton; John J. Kopchick; David Kleinberg
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Estimating effectiveness in an observational study: A case study of dornase alfa in cystic fibrosis
Journal of Pediatrics, ISSN: 00223476
Charles A. Johnson; Butler; Michael W. Konstan; Timothy J. Breen; Morgan
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Capillary electrophoresis sodium dodecyl sulfate nongel sieving analysis of a therapeutic recombinant monoclonal antibody: A biotechnology perspective
Analytical Chemistry, ISSN: 00032700
Glenn Hunt; Wassim Nashabeh
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Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage
Journal of Neurocytology, ISSN: 03004864
Zheng; Gretchen D. Frantz; Lewis; Mark X. Sliwkowski; Gao
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VEGF antagonism reduces edema formation and tissue damage after ischemia/reperfusion injury in the mouse brain
Journal of Clinical Investigation, ISSN: 00219738
Nicholas Van Bruggen; Harold Thibodeaux; James T. Palmer; Wyne P. Lee; Ling Fu; Cairns; Daniel B. Tumas; Gerlai; Simon P. Williams; Menno Van Lookeren Campagne; Napoleone Ferrara
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Secondary reduction in the apparent diffusion coefficient of water, increase in cerebral blood volume, and delayed neuronal death after middle cerebral artery occlusion and early reperfusion in the rat
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
Menno Van Lookeren Campagne; Roger Thomas; Harold Thibodeaux; James T. Palmer; Simon P. Williams; David G Lowe; Nicholas Van Bruggen
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Anti-IgE as novel therapy for the treatment of asthma
Current Opinion in Pulmonary Medicine, ISSN: 10705287
Robert B. Fick Jr.
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RIPs: An emerging family of kinases involved in pro-inflammatory and apoptotic signaling
Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451
Vishva M. Dixit
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Characterization of a candidate Borrella burgdorferi β3-chain integrin ligand identified using a phage display library
Molecular Microbiology, ISSN: 0950382X
Jenifer Coburn; Wambui Chege; Loranne Magoun; Bodary; John M. Leong
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Neuregulin receptor-mediated gene transfer by human epidermal growth factor receptor 2-targeted antibodies and neuregulin-1
Cancer Gene Therapy, ISSN: 09291903
Jeffrey Kern; Robert Wakita; Mark X. Sliwkowski
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Novel peptides selected to bind vascular endothelial growth factor target the receptor-binding site
Biochemistry, ISSN: 00062960
Wayne J. Fairbrother; Hans W. Christinger; Andrea G Cochran; Fuh; Christopher J. Keenan; Quan; Stephanie K. Shriver; Jeffrey Tom; James A. Wells; Cunningham
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Crystal structure of the complex between VEGF and a receptor-blocking peptide
Biochemistry, ISSN: 00062960
Wiesmann; Hans W. Christinger; Andrea G Cochran; Cunningham; Wayne J. Fairbrother; Christopher J. Keenan; Meng; De Vos
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Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer
Nature, ISSN: 00280836
Pitti; Scot A. Marsters; David Lawrence; Margaret Roy; Frank C. Kischkel; Patrick Dowd; Arthur Huang; Christopher J. Donahue; Steve Sherwood; Daryl T. Baldwin; Godowski; William I. Wood; Austin L. Gurney; Kenneth J. Hillan; Robert L. Cohen; Goddard; David Botstein; Avi Ashkenazi
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Safety and immunogenicity of HIV recombinant envelope vaccines in HIV- infected infants and children
Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology, ISSN: 10779450
John S. Lambert; James McNamara; Samuel L. Katz; Terry Fenton; Minhee Kang; Thomas C. VanCott; Robert Livingston; Elizabeth Hawkins; Jack Moye Jr.; William Borkowsky; Daniel Johnson; Ram Yogev; A-M. Duliege; Francis; Anne Gershon; Diane W. Wara; Natasha L. Martin; Myron Levin; George McSherry; Gale Smith
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Crystal structure of the MATa1/MATα2 homeodomain heterodimer in complex with DNA containing an A-tract
Nucleic Acids Research, ISSN: 03051048
Thomas Li; Yisheng Jin; Andrew K. Vershon; Cynthia Wolberger
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Host defense molecule polymorphisms influence the risk for immune- mediated complications in chronic granulomatous disease
Journal of Clinical Investigation, ISSN: 00219738
Charles B. Foster; Thomas Lehrnbecher; Femke Mol; Seth M. Steinberg; David J. Venzon; Thomas J. Walsh; Noack; Julie Rae; Jerry A. Winkelstein; John T. Curnutte; Stephen J. Chanock
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Compendium of excipients for parenteral formulations
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Powell; Tue H. Nguyen; Baloian
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