Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13551 - 13600 OF 15583 RESULTS

Guanylyl cyclase receptors
Journal of Biological Chemistry, ISSN: 00219258
Garbers; David G Lowe
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Application of capillary high-performance liquid chromatography to biotechnology, with reference to the analysis of recombinant DNA-derived human growth hormone
Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 03784347
John E. Battersby; Andrew W. Guzzetta; William S. Hancock
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Entry of naive CD4 T cells into peripheral lymph nodes requires I-selectin
Journal of Experimental Medicine, ISSN: 15409538 00221007
Linda M. Bradley; Susan R. Watson; Susan L. Swain
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Phase I studies with biologicals
European Journal of Clinical Research, ISSN: 09613692
Froehlich
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Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. II. Selectivity effects observed in the separation of several peptide and protein mixtures
Journal of Chromatography A, ISSN: 00219673
Chloupek; William S. Hancock; Brian A. Marchylo; Kirkland; Barry E. Boyes; Lloyd R. Snyder
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Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. I. Optimizing the separation of a growth hormone tryptic digest
Journal of Chromatography A, ISSN: 00219673
William S. Hancock; Chloupek; Kirkland; Lloyd R. Snyder
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Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins
Neuroscience Letters, ISSN: 03043940
Alun M. Davies; Rosenthal
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HIV-1(MN) recombinant gp120 vaccine serum, which fails to neutralize primary isolates of HIV-1, does not antagonize neutralization by antibodies from infected individuals [2]
AIDS, ISSN: 02699370
Wrin; Nunberg
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Biologic activities of the murine β-chemokine TCA3
Journal of Immunology, ISSN: 00221767
Yi Luo; Joseph Laning; Shamala Devi; John Mak; Thomas J. Schall; Martin E. Dorf
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Rupture of the mitochondrial outer membrane impairs porin assembly
Journal of Biological Chemistry, ISSN: 00219258
Mitchell Smith; Shawn Hicks; Kevin Baker; Roy McCauley
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Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity
Journal of Biological Chemistry, ISSN: 00219258
Shih; Laramee; Charles H. Schmelzer; Louis E. Burton; Winslow
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Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes
Journal of Biological Chemistry, ISSN: 00219258
Arvind Nanda; Robert Romanek; John T. Curnutte; Sergio Grinstein
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Colorimetric determination of dnase i activity with a DNA-methyl green substrate
Analytical Biochemistry, ISSN: 10960309 00032697
Sinicropi; Baker; Prince; Shiffer; Shak
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R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells
Oncogene, ISSN: 09509232
Adrienne D. Cox; Teresa R. Brtva; David G Lowe; Channing J. Der
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Cell surface P- and E-selectin support shear-dependent rolling of bovine γ/δ T cells
Journal of Immunology, ISSN: 00221767
Mark A. Jutila; Robert F. Bargatze; Sandy Kurk; R. Aaron Warnock; Niloofar Ehsani; Susan R. Watson; Bruce Walcheck
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A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells
Journal of Immunology, ISSN: 00221767
Steven M. Chamow; Zhang; Xiang Y. Tan; Mhatre; Scot A. Marsters; Peers; Randal A. Byrn; Avi Ashkenazi; Junghans
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Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia
Circulation, ISSN: 00097322
Satoshi Takeshita; Li-Qun Pu; Lawrence A. Stein; Allan D. Sniderman; Bunting; Napoleone Ferrara; Jeffrey M. Isner; James F. Symes
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Determination of the Solution Structure of the Peptide Hormone Guanylin: Observation of a Novel Form of Topological Stereoisomerism
Biochemistry, ISSN: 15204995 00062960
Nicholas J. Skelton; Garcia; David V. Goeddel; Quan; Burnier
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Conformational Changes in the Reversed Phase Liquid Chromatography of Recombinant Human Growth Hormone as a Function of Organic Solvent: The Molten Globule State
Analytical Chemistry, ISSN: 15206882 00032700
Wicar; Michael G. Mulkerrin; Bathory; Khundkar; Karger
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Exploring the Microtubule-Binding Region of Bovine Microtubule-Associated Protein-2 (MAP-2): CDNA Sequencing, Bacterial Expression, and Site-Directed
Biochemistry, ISSN: 15204995 00062960
Richard L. Coffey; John C. Joly; Brian D. Cain; Daniel L. Purich
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Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange
Journal of Molecular Biology, ISSN: 00222836
Crisona; Kanaar; Gonzalez; Zechiedrich; Klippel; Cozzarelli
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Role of the 75-kDa tumor necrosis factor receptor: Inhibition of early hematopoiesis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Frede W. Jacobsen; Mike Rothe; Leiv Rusten; David V. Goeddel; Erlend B. Smeland; Ole P. Veiby; Lars Slørdal; Sten E. W. Jacobsen
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Suppression of mammalian 5′ splice-site defects by U1 small nuclear RNAs from a distance
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Justus B. Cohen; Jon E. Snow; Spencer; Levinson
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The binding site on human immunoglobulin E for its high affinity receptor
Journal of Biological Chemistry, ISSN: 00219258
Presta; Robert L. Shields; O'Connell; Steven Lahr; James P. Porter; Cornelia M. Gorman; Paula Jardieu
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Indications for growth hormone
The Lancet, ISSN: 01406736
Barry M. Sherman
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Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin
Blood, ISSN: 00064971
Baumhueter; Noel Dybdal; Carrie Kyle; Lasky
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Cellular and molecular characterization of the role of the FLK-2/FLT-3 receptor tyrosine kinase in hematopoietic stem cells
Blood, ISSN: 00064971
Francis C. Zeigler; Brian D. Bennett; Craig T. Jordan; Spencer; Baumhueter; Carroll; Jeff Hooley; Kenneth D. Bauer; William Matthews
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A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues
Science, ISSN: 00368075
Jackson; Burnier; Quan; Mark S. Stanley; Jeffrey Tom; James A. Wells
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Radioimmunotherapy of Human B-Cell Chronic Lymphocytic Leukemia in Nude Mice
Cancer Research, ISSN: 15387445 00085472
Zhu; Tarunendu Ghose; David Hoskin; Christine L. Y. Lee; Spencer H. S. Lee; Molly Mammen
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Purification and characterization of α-L-fucosidase from Chinese hamster ovary cell culture supernatant
Glycobiology, ISSN: 09596658
Michael J. Gramer; David V. Schaffer; Mary B. Sliwkowski; Charles F. Goochee
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Peptide liquid crystals: Inverse correlation of kinetic formation and thermodynamic stability in aqueous solution
Pharmaceutical Research, ISSN: 07248741
Powell; Fleitman; Sanders; Si
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Megestrol acetate in patients with AIDS and cachexia
Annals of Internal Medicine, ISSN: 00034819
Oster; Sheila R. Enders; Steven J. Samuels; Lawrence A. Cone; Thomas M. Hooton; Henry P. Browder; Neil M. Flynn
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Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Matzuk; Finegold; Mather; Lynne Krummen; Lu; Allan Bradley
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Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line
Journal of Biological Chemistry, ISSN: 00219258
Wen-Liang Kuo; Barry D. Gehm; Marsha Rich Rosner; Wenlu Li; Gilbert-Andre Keller
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Effect of aerosolized recombinant human dnase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis
New England Journal of Medicine, ISSN: 15334406 00284793
Henry J. Fuchs; David H. Christiansen; Drucy S. Borowitz; Martha L. Nash; Bonnie W. Ramsey; Arnold L. Smith; Edward M. Morris; Beryl J. Rosenstein; Mary Ellen Wohl
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Incorporation of bromodeoxyuridine in glutathione s-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis
Carcinogenesis, ISSN: 01433334
Dragan; James R. Hully; Crow; Mass; Pitot
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The Disulfide Linkages and Glycosylation Sites of the Human Natriuretic Peptide Receptor-C Homodimer
Biochemistry, ISSN: 15204995 00062960
Stults; Kathy L. O'Connell; Garcia; Alfred M Engel; David G Lowe; Garbers; Wong
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Structure of the Extracellular Domain of Human Tissue Factor: Location of the Factor VIIa Binding Site
Biochemistry, ISSN: 15204995 00062960
Yves A. Muller; Ultsch; Robert F. Kelley; De Vos
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Redundant functions of the genes knirps and knirps-related for the establishment of anterior Drosophila head structures
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Marcos González-Gaitán; Mike Rothe; Ernst A. Wimmer; Heike Taubert; Herbert Jäckle
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A novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptor
Cell, ISSN: 00928674
Mike Rothe; Suzy C. Wong; William J. Henzel; David V. Goeddel
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Liposome targeting to human immunodeficiency virus type 1-infected cells via recombinant soluble CD4 and CD4 immunoadhesin (CD4-IgG)
Biochimica et Biophysica Acta - Biomembranes, ISSN: 00052736
Diana Flasher; Krystyna Konopka; Steven M. Chamow; Paul Dazin; Avi Ashkenazi; Elizabeth Pretzer; Nejat Düzgüneş
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Neutralizing Antibodies to HIV-1 in Seronegative Volunteers Immunized With Recombinant gp 120 From the MN Strain of HIV-1
JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484
Robert Belshe; Geoffrey Gorse; Barney S. Graham; Peter Wright; Michael C. Keefer; Raphael Dolin; Matthews; Kent Weinhold; Dani P. Bolognesi; Richard Sposto; Donald M. Stablein; Tom Twaddell; Berman; Timothy Gregory; Allen Izu; Mary Clare Walker; Patricia Fast
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Peptide-Cyclizations on solid support: A fast and efficient route to small cyclopeptides
Tetrahedron Letters, ISSN: 00404039
Lutz S. Richter; Jeffrey Tom; Burnier
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Solution Conformation of an Atrial Natriuretic Peptide Variant Selective for the Type A Receptor
Biochemistry, ISSN: 15204995 00062960
Wayne J. Fairbrother; Brian C. Cunningham; Robert S. McDowell
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Contribution to Global Protein Stabilization of the N-Capping Box in Human Growth Hormone
Biochemistry, ISSN: 15204995 00062960
Eugene A. Zhukovsky; Presta; Michael G. Mulkerrin
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Complete mutagenesis of the extracellular domain of interleukin-8 (IL-8) type A receptor identifies charged residues mediating IL-8 binding and signal transduction
Journal of Biological Chemistry, ISSN: 00219258
Leong; Rhona C. Kabakoff; Hébert
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Preparative isolation of recombinant human insulin-like growth factor 1 by reversed-phase high-performance liquid chromatography
Journal of Chromatography A, ISSN: 00219673
Charles V. Olson; David H. Reifsnyder; Eleanor Canova-Davis; Victor Ling; Stuart E. Builder
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A surprising observation about Mitsunobu reactions in solid phase synthesis
Tetrahedron Letters, ISSN: 00404039
Lutz S. Richter; Thomas Gadek
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Mutational analysis and molecular modeling of the n-terminal kringle-containing domain of hepatocyte growth factor identifies amino acid side chains important for interaction with the c-metreceptor
Protein Engineering, Design and Selection, ISSN: 17410126
Lokker; Presta; Godowski
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Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent
Journal of Experimental Medicine, ISSN: 15409538 00221007
Fiona A. Symon; Garry M. Walsh; Susan R. Watson; Andrew J. Wardlaw
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