Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13851 - 13900 OF 15583 RESULTS

September 10, 1993

A novel domain within the 55 kd TNF receptor signals cell death

Cell, ISSN: 00928674

Louis A. Tartaglia; T. Merrill Ayres; Grace H.W. Wong; David V. Goeddel

September 1, 1993

Effect of intravenous infusion of growth hormone-releasing hormone on the morphology of rat pituitary somatotrophs

Endocrine Pathology, ISSN: 10463976 15590097

Lucia Stefaneanu; Kalman Kovacs; Eva Horvath; G.Clark Ross; J.Cronin Michael

August 25, 1993

Interferon-γ induces receptor dimerization in solution and on cells

Journal of Biological Chemistry, ISSN: 00219258

Andrew C. Greenlund; Schreiber; David V. Goeddel; Diane Pennica

July 24, 1993

Efficacy and safety of short-term administration of aerosolised recombinant human DNase I in adults with stable stage cystic fibrosis

The Lancet, ISSN: 01406736

Ranasinha; Assoufi; Geddes; Hodson; Empey; Steven Shak; David H. Christiansen; Henry J. Fuchs

July 15, 1993

Transforming Growth Factor-β Primes Macrophages to Express Inflammatory Gene Products in Response to Particulate Stimuli by an Autocrine/Paracrine Mechanism

Journal of Immunology, ISSN: 00221767

Paul W. Noble; Peter M. Henson; Catherine Lucas; Mora-Worms; Phillipe C. Carré; David W. H. Riches

July 10, 1993

Induction of HIV-1-neutralising and syncytium-inhibiting antibodies in uninfected recipients of HIV-1IIIB rgp120 subunit vaccine

The Lancet, ISSN: 01406736

David Schwartz; Mary Lou Clements; Geoffrey Gorse; Robert Belshe; Allen Izu; A-M. Duliege; Berman; Tom Twaddell; Donald M. Stablein; Richard Sposto; Robert F. Siliciano; Matthews

July 1, 1993

Tryptic Mapping of Recombinant Proteins by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry

Analytical Chemistry, ISSN: 15206882 00032700

Todd M. Billeci; Stults

July 1, 1993

Making tissue-type plasminogen activator more fibrin specific

Protein Engineering, Design and Selection, ISSN: 17410126

Nicholas F. Paoni; Alice M. Chow; Luis Peña; Keyt; Zoller; William F. Bennett

July 1, 1993

Simplification of High-Energy Collision Spectra of Peptides by Amino-Terminal Derivatization

Analytical Chemistry, ISSN: 15206882 00032700

Stults; Johnny Lai; Shannon McCune; Wetzel

July 1, 1993

Differential responses of human tumor cell lines to anti-p185HER2 monoclonal antibodies

Cancer Immunology, Immunotherapy, ISSN: 03407004 14320851

Gail D. Lewis; Figari; Brian M. Fendly; Wai Lee Wong; Paul J. Carter; Cornelia M. Gorman; Shepard

July 1, 1993

Human IgE receptor α-chain IgG chimera blocks passive cutaneous anaphylaxis reaction in vivo

Journal of Immunology, ISSN: 00221767

Haak-Frendscho; John B.B. Ridgway; Robert L. Shields; Robbins; Cornelia M. Gorman; Paula Jardieu

June 20, 1993

Crystals of human growth hormone-receptor complexes. Extracellular domains of the growth hormone and prolactin receptors and a hormone mutant designed to prevent receptor dimerization

Journal of Molecular Biology, ISSN: 00222836

Ultsch; De Vos

June 15, 1993

Selection of an anti-IGF-1 Fab from a Fab phage library created by mutagenesis of multiple CDR loops

Gene, ISSN: 03781119

Lisa J. Garrard; Henner

June 8, 1993

Glycosylphosphatidylinositol anchored proteins are preferentially targeted to the basolateral surface in Fischer rat thyroid epithelial cells

Journal of Cell Biology, ISSN: 00219525

Chiara Zurzolo; Michael P. Lisanti; Caras; Lucio Nitsch; Rodriguez-Boulan

June 1, 1993

Human macrophage inflammatory protein cr (MIP-1α) and MIP-1β chemoklnes attract distinct populations of lymphocytes

Journal of Experimental Medicine, ISSN: 15409538 00221007

Thomas J. Schall; Bacon; Camp; Kaspari; David V. Goeddel

June 1, 1993

O-linked fucose and other post-translational modifications unique to EGF modules

Glycobiology, ISSN: 09596658

Reed J. Harris; Spellman

June 1, 1993

Loss in expression of the retinoblastoma gene product in human gliomas is associated with advanced disease

Journal of Neuro-Oncology, ISSN: 0167594X 15737373

Wolfgang Hamel; Manfred Westphal; Shepard

June 1, 1993

Combinatorial mediators of inflammation?

Current Biology, ISSN: 09609822

Lasky

June 1, 1993

Prevention of metastasis by inhibition of the urokinase receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Crowley; Robert L. Cohen; Brian K. Lucas; Liu; Shuman; Levinson

May 20, 1993

Theoretical considerations for the design and development of a drug: Influence of pharmacokinetics and dosage regimen on receptor interactions

Pharmaceutical Research, ISSN: 07248741

Joyce Mordenti; Rescigno

April 23, 1993

Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptor

Cell, ISSN: 00928674

Louis A. Tartaglia; Mike Rothe; Yan-Fen Hu; David V. Goeddel

April 16, 1993

Solid phase synthesis of peptide para -nitroanilides

Tetrahedron Letters, ISSN: 00404039

Burdick; Martin Struble; Burnier

April 1, 1993

Physical Properties of Recombinant Apolipoprotein(a) and Its Association with LDL to Form an Lp(a)-like Complex

Biochemistry, ISSN: 15204995 00062960

Martin L. Phillips; Audra V. Lembertas; Verne N. Schumaker; Lawn; Steven J. Shire; Zioncheck

March 26, 1993

Protein sorting by high-performance liquid chromatography. I. Biomimetic interaction chromatography of recombinant human deoxyribonuclease I on polyionic stationary phases

Journal of Chromatography A, ISSN: 00219673

Cacia; Quan; Vasser; Mary B. Sliwkowski; John Frenz

March 15, 1993

Proper glycosylation and phosphorylation of the type A natriuretic peptide receptor are required for hormone-stimulated guanylyl cyclase activity

Journal of Biological Chemistry, ISSN: 00219258

Koller; Michael T. Lipari; David V. Goeddel

March 1, 1993

Biochemical Characterization of the Extracellular Domain of the 75-Kilodalton Tumor Necrosis Factor Receptor

Biochemistry, ISSN: 15204995 00062960

Diane Pennica; Van Lam; Weber; William J. Kohr; Basa; Spellman; Avi Ashkenazi; Steven J. Shire; David V. Goeddel

March 1, 1993

Lack of impact of early catheterization and fibrin specificity on bleeding complications after thrombolytic therapy

Journal of the American College of Cardiology, ISSN: 07351097

Thomas C. Wall; Robert M. Califf; Stephen G. Ellis; Kristina Sigmon; Dean J. Kereiakes; Barry S. George; Joseph Samaha; David Sane; David Stump; Richard S. Stack; Eric Topol

March 1, 1993

A new yeast gene with a myosin-like heptad repeat structure

Molecular and General Genetics, ISSN: 00268925 16174623

Ralf Kölling; Nguyen; Ellson Y. Chen; David Botstein

February 28, 1993

An Alu sequence interupts a human 5-hydroxytryptamine1D receptor pseudogene

Gene, ISSN: 03781119

Tuan Nguyen; Adriano Marchese; James L. Kennedy; Arturas Petronis; Peroutka; Peter H. Wu; Brian F. O'Dowd

February 20, 1993

X-ray structures of the antigen-binding domains from three variants of humanized anti-p185HER2 antibody 4D5 and comparison with molecular modeling

Journal of Molecular Biology, ISSN: 00222836

Eigenbrot; Michael Randal; Presta; Paul J. Carter; Anthony A. Kossiakoff

February 12, 1993

Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor

Cell, ISSN: 00928674

Kuldeep Neote; DiGregorio; John Mak; Richard Horuk; Thomas J. Schall

January 13, 1993

Extracellular matrix regulates expression of the TGF-β1 gene

Journal of Cell Biology, ISSN: 00219525

Charles H. Streuli; Christian Schmidhauser; Michael S. Kobrin; Mina J. Bissell; Rik Derynck

January 1, 1993

Homotypic leukocyte aggregation triggered by a monoclonal antibody specific for a novel epitope expressed by the integrin β1 subunit: Conversion of nonresponsive cells by transfecting human integrin α4 subunit cDNA

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

John L. Bednarczyk; James N. Wygant; Margit C. Szabo; Laura Molinari‐Storey; Renz; Fong; Bradley W. McIntyre

January 1, 1993

Evidence supporting a role for cathepsin B in the generation of T cell antigenic epitopes of human growth hormone

Molecular Immunology, ISSN: 01615890

Gillian Bushell; Nelson; Chiu; Christopher Grimley; William J. Henzel; Burnier; Fong

January 1, 1993

Receptor/ligand interactions in the C-C chemokine family

Advances in Experimental Medicine and Biology, ISSN: 00652598

Thomas J. Schall; John Mak; DiGregorio; Kuldeep Neote

January 1, 1993

Production of Fusion Protein SpA:: EcoRI in Batch Culture in a 60‐L Airlift Tower Loop Reactor

Biotechnology Progress, ISSN: 15206033 87567938

Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Heike Jürgens; Birgit Reinhardt; Karl Schügerl

January 1, 1993

Glycoprotein IIb IIIa Antagonists

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Brent Blackburn; Thomas Gadek

January 1, 1993

Triply Convergent Synthesis of 15-(Phenoxymethyl) and 4,5-Allenyl Prostaglandins. Preparation of an Individual Isomer of Enprostil

Journal of Organic Chemistry, ISSN: 15206904 00223263

Owen W. Gooding; Colin C. Beard; Gary F. Cooper; Jackson

January 1, 1993

Thermodynamic Analysis of an Antibody Functional Epitope

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Mark P. O'Connell

January 1, 1993

Peptide Stability in Drug Development: In vitro Peptide Degradation in Plasma and Serum

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Powell

January 1, 1993

Identification and Structural Analysis of the Tetrasaccharide NeuAcα(2→6)Galβ(1→4)GlcNAcβ(1→3)Fucαl→O-Linked to Serine 61 of Human Factor IX

Biochemistry, ISSN: 15204995 00062960

Reed J. Harris; Basa; Victor Ling; Spellman; Van Halbeek; John Glushka; Kenneth J. Smith

January 1, 1993

Neurotrophin-4/5 is a mammalian-specific survival factor for distinct populations of sensory neurons

Journal of Neuroscience, ISSN: 02706474

Alun M. Davies; Antony Horton; Louis E. Burton; Charles H. Schmelzer; Richard L. Vandlen; Rosenthal

January 1, 1993

Overproduction of recombinant proteins by escherichia coli - employing the combinations of two and three different types of multicopy plasmids - in a 60-litre working volume airlift tower loop reactor

Process Biochemistry, ISSN: 13595113

Lutz Brandes; Xiaoan Wu; Hans E. Maschke; Karl Schügerl

January 1, 1993

The Human Erythrocyte Inflammatory Peptide (Chemokine) Receptor. Biochemical Characterization, Solubilization, and Development of a Binding Assay for the Soluble Receptor

Biochemistry, ISSN: 15204995 00062960

Richard Horuk; Timothy J. Colby; Darbonne; Thomas J. Schall; Kuldeep Neote

January 1, 1993

Vascular endothelial growth factor

Trends in Cardiovascular Medicine, ISSN: 10501738

Napoleone Ferrara

January 1, 1993

Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

Nature, ISSN: 00280836

K.Jin Kim; Bing Li; Jane Winer; Armanini; Nancy Gillett; Phillips; Napoleone Ferrara

January 1, 1993

Difficulties in Precise Quantitation of CD4+T Lymphocytes for Clinical Trials: A Review

Biologicals, ISSN: 10958320 10451056

David T.W. Fei; Paxton; Chen

January 1, 1993

5‐Hydroxytryptamine Receptors

Journal of Neurochemistry, ISSN: 14714159 00223042

Peroutka

January 1, 1993

The molecular basis for growth hormone-receptor interactions

Recent Progress in Hormone Research, ISSN: 00799963

James A. Wells; Cunningham; Fuh; Henry B. Lowman; Bass; Michael G. Mulkerrin; Ultsch; Abraham M. Devos

January 1, 1993

Epidermal growth factor stimulates vascular endothelial growth factor production by human malignant glioma cells: A model of glioblastoma multiforme pathophysiology

Molecular Biology of the Cell, ISSN: 10591524

Corey K. Goldman; Jin Kim; Wai Lee T. Wong; Vickie King; Tommy Brock; G. Yancey Gillespie

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