Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14001 - 14050 OF 15787 RESULTS

January 1, 1994

Dissecting the energetics of an antibody‐antigen interface by alanine shaving and molecular grafting

Protein Science, ISSN: 1469896X 09618368

Jin; James A. Wells

January 1, 1994

Activation of TNF‐R1 receptor in the presence of copper kills TNF resistant CEM leukemic T cells

Journal of Cellular Physiology, ISSN: 10974652 00219541

H. Garrett Wada; Katherine S. Fok; Brian M. Fendly; Nancy Y. Chiang; Howard H. Sussman

January 1, 1994

Use of polymerase chain reaction (PCR) in the development of a recombinant organism.

Developments in biological standardization, ISSN: 03015149

Helder; Utter

January 1, 1994

Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice

Immunity, ISSN: 10747613

Huang; Hultgren; Noel Dybdal; Stewart

January 1, 1994

Interferon-α and induction of type I diabetes

Biomedicine and Pharmacotherapy, ISSN: 07533322

Tracy Stewart

January 1, 1994

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life

Molecular and Cellular Biology, ISSN: 02707306

Phillip Belgrader; Jiu Cheng; Xianbo Zhou; Lori S. Stephenson; Lynne E. Maquat

January 1, 1994

New techniques in protein chemistry.

Developments in biological standardization, ISSN: 03015149

O'Connor; Rodney Keck; Reed J. Harris; Field

January 1, 1994

Report on the Genetic Stability Symposium. April 10-12, 1991. West Coast Chapter, Parenteral Drug Association.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick; Helder

January 1, 1994

Approaches to analysis of aggregates and demonstrating mass balance in pharmaceutical protein (basic fibroblast growth factor) formulations

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Shahrokh; Stratton; Eberlein; Y. John Wang

January 1, 1994

Chinese hamster ovary cells contain transcriptionally active full-length type C proviruses

Journal of Virology, ISSN: 0022538X

Yolanda S. Lie; Elicia M. Penuel; Mari-Anne L. Low; Nguyen; Jocelyn O. Mangahas; Anderson; Christos J. Petropoulos

January 1, 1994

Humanized Monoclonal Antibodies

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Presta

January 1, 1994

Evaporation of Aqueous Aerosols Produced by Jet Nebulizers: Effects on Particle Size and Concentration of Solution in the Droplets

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Phipps; Gonda

January 1, 1994

Sialomucin ligands for selectins: a new family of cell adhesion molecules.

Princess Takamatsu symposia,

Lasky

January 1, 1994

Rac translocates independently of the neutrophil NADPH oxidase components p47(phox) and p67(phox). Evidence for its interaction with flavocytochrome b558

Journal of Biological Chemistry, ISSN: 00219258

Heyworth; Benjamin P. Bohl; Bokoch; John T. Curnutte

January 1, 1994

In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells

Blood, ISSN: 00064971

Francis C. Zeigler; Frederic J. De Sauvage; Widmer; Gilbert-Andre Keller; Christopher J. Donahue; Schreiber; Malloy; Hass; Dan L. Eaton; William Matthews

January 1, 1994

The X-ray structure of a growth hormone-prolactin receptor complex

Nature, ISSN: 00280836

Somers; Ultsch; De Vos; Anthony A. Kossiakoff

January 1, 1994

Ron is a heterodimeric tyrosine kinase receptor activated by the HGF homologue MSP

EMBO Journal, ISSN: 02614189

Giovanni Gaudino; Antonia Follenzi; Luigi Naldini; Chiara Collesi; Massimo Santoro; Kathleen A. Gallo; Godowski; Paolo M. Comoglio

January 1, 1994

An interleukin-4-induced transcription factor: IL-4 Stat

Science, ISSN: 00368075

Jinzhao Hou; Ulrike Schindler; William J. Henzel; Tze Chun Ho; Mike Brasseur; Steven L. McKnight

January 1, 1994

Regulation of experimental autoimmune neuritis by transforming growth factor-β1

Cellular Immunology, ISSN: 00088749

Shahik K. Gregorian; Wyne P. Lee; L. Steven Beck; Abdolmohamad Rostami; Edward P. Amento

January 1, 1994

Addition of a bacterial alginate lyase to purulent cf sputum in vitro can result in the disruption of alginate and modification of sputum viscoelasticity

Pulmonary Pharmacology, ISSN: 09520600

Mrsny; Lazazzera; Daugherty; Schiller; Thomas W. Patapoff

January 1, 1994

Functional role of type I and type II interferons in antiviral defense

Science, ISSN: 00368075

Ulrike Müller; Ulrich Steinhoff; Luiz F. L. Reis; Silvio Hemmi; Jovan Pavlovic; Rolf M. Zinkernagel; Michel Aguet

January 1, 1994

Variable Success of Peptide-Resin Cleavage and Deprotection Following Solid-Phase Synthesis

Techniques in Protein Chemistry, ISSN: 10808914

Gregg B. Fields; Ruth H. Angeletti; Steve A. Carr; Alan J. Smith; Stults; Lynn C. Williams; Janis D. Young

January 1, 1994

Identification of 2-D Gel Proteins at the Femtomole Level by Molecular Mass Searching of Peptide Fragments in a Protein Sequence Database

Techniques in Protein Chemistry, ISSN: 10808914

William J. Henzel; Todd M. Billeci; Stults; Susan C. Wong; Christopher Grimley; Colin K. Watanabe

January 1, 1994

Structural Characterization of a Novel Tetrasaccharide Attached to Ser-61 of Human Factor IX by Mass Spectrometry and 1H NMR Spectroscopy

Techniques in Protein Chemistry, ISSN: 10808914

Reed J. Harris; Basa; Victor Ling; Spellman; Kenneth J. Smith; John Glushka; Russell W. Carlson; Van Halbeek

January 1, 1994

Receptor dimerization determines the effects of growth hormone in primary rat adipocytes and cultured human IM-9 lymphocytes

Endocrinology, ISSN: 00137227

Mapoko M. Ilondo; Anders B. Damholt; Cunningham; James A. Wells; Pierre De Meyts; Ronald M. Shymko

January 1, 1994

The stoichiometry of growth hormone-binding protein complexes in human plasma: Comparison with cell surface receptors

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Gerhard Baumann; Henry B. Lowman; Moises Mercado; James A. Wells

January 1, 1994

A liquid‐phase binding analysis for L‐selectin: A strong dependency on highly clustered sulfate groups

European Journal of Biochemistry, ISSN: 14321033 00142956

Tomoaki YOSHIDA; Christopher Fennie; Lasky; Yuan C. LEE

January 1, 1994

IV. Yeast sequencing reports. Nucleotide sequence of the SAC2 gene of Saccharomyces cerevisiae

Yeast, ISSN: 10970061 0749503X

Ralf Kölling; Angela Lee; Ellson Y. Chen; David Botstein

January 1, 1994

Assay Systems for the Growth Hormone-Binding Protein

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727

Carlsson; Moises Mercado; Gerhard Baumann; Mark Stene; Kenneth M. Attie; Marcel Reichert; Kerstin Albertsson-Wikland; Kelly Dawson; Wai Lee T. Wong

January 1, 1994

Delayed-type hypersensitivity response in experimental autoimmune neuritis treated with peptide-coupled spleen cells

Journal of Neuroimmunology, ISSN: 01655728

Shahik K. Gregorian; Abdolmohamad Rostami

January 1, 1994

Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient mice

Nature, ISSN: 00280836

Sharon Erickson; Frederic J. De Sauvage; Kristine Kikly; Karen Carver-Moore; Sharon Pitts-Meek; Nancy Gillett; Kathleen C. Sheehan; Schreiber; David V. Goeddel; Mark Moore

January 1, 1994

Thrombocytopenia in c-mpl-deficient mice

Science, ISSN: 00368075

Austin L. Gurney; Karen Carver-Moore; Frederic J. De Sauvage; Mark Moore

January 1, 1994

Structure of the RGD protein decorsin: Conserved motif and distinct function in leech proteins that affect blood clotting

Science, ISSN: 00368075

Andrzej M. Krezel; Gerhard Wagner; Jana Seymour-Ulmer; Lazarus

January 1, 1994

Stimulation of megakaryocytopoiesis and thrombopoiesis by the c-Mpl ligand

Nature, ISSN: 00280836

Frederic J. De Sauvage; Hass; Spencer; Malloy; Austin L. Gurney; Steven A. Spencer; Darbonne; William J. Henzel; Suzy C. Wong; Wun-Jing Kuang; Karl J. Oles; Hultgren; Lawrence A. Solberg Jr.; David V. Goeddel; Dan L. Eaton

January 1, 1994

Effect of Interferon Gamma on Infection-Related Death in Patients With Severe Injuries: A Randomized, Double-blind, Placebo-Controlled Trial

Archives of Surgery, ISSN: 15383644 00040010

David J. Dries; Gregory J. Jurkovich; Ronald V. Maier; Terry P. Clemmer; Steven N. Struve; John A. Weigelt; Gregory G. Stanford; Daniel L. Herr; Howard R. Champion; Frank R. Lewis; David Hoyt; John Hansbrough; Albert E. Yellin; Thomas V. Berne; Donald D. Trunkey; Howard S. Jaffe; Catherine Munera; Peggy Fisher; Karen M. Starko

January 1, 1994

Neutrophil and B cell expansion in mice that lack the murine IL-8 receptor homolog

Science, ISSN: 00368075

Cacalano; James Lee; Kristine Kikly; Anne Ryan; Sharon Pitts-Meek; Hultgren; William I. Wood; Mark Moore

January 1, 1994

Artificial bone graft formulation for rhTGF-β1

Proceedings of the Controlled Release Society, ISSN: 10760458

Tue H. Nguyen; Cromwell; Wong; L. Steven Beck; Plouhar; Ongpipattanakul

December 15, 1993

Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow

Journal of Immunology, ISSN: 00221767

Mebius; Dowbenko; Angelica Williams; Christopher Fennie; Lasky; Susan R. Watson

December 5, 1993

Comparison of a structural and a functional epitope

Journal of Molecular Biology, ISSN: 00222836

Cunningham; James A. Wells

December 5, 1993

Affinity maturation of human growth hormone by monovalent phage display

Journal of Molecular Biology, ISSN: 00222836

Henry B. Lowman; James A. Wells

December 1, 1993

Disseminated tuberculosis in interferon γ Gene-disrupted mice

Journal of Experimental Medicine, ISSN: 15409538 00221007

Andrea M. Cooper; Dyana K. Dalton; Stewart; John P. Griffin; David G. Russell; Ian M. Orme

December 1, 1993

Cytokine reversal of morphine-induced suppression of the antibody response

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Bussiere; Adler; Rogers; Eisenstein

December 1, 1993

Neurotrophic factor therapy of Alzheimer's disease

Clinical Neuroscience, ISSN: 10656766

Klaus D. Beck; Franz Hefti

December 1, 1993

An essential role for interferon γ in resistance to mycobacterium tuberculosis infection

Journal of Experimental Medicine, ISSN: 15409538 00221007

JoAnne L. Flynn; John Chan; Karla J. Triebold; Dyana K. Dalton; Stewart; Bloom

December 1, 1993

Successful immunization of rhesus monkeys with the extracellular domain of p185(HER2): A potential approach human breast cancer

Vaccine Research, ISSN: 10567909

Brian M. Fendly; Claire Kotts; Wai Lee T. Wong; Figari; Harel; Staib; Monique E. Carver; David Vetterlein; Mitchell; Shepard

December 1, 1993

The development of stable protein formulations: A close look at protein aggregation, deamidation, and oxidation

Critical Reviews in Therapeutic Drug Carrier Systems, ISSN: 07434863

Cleland; Powell; Steven J. Shire

November 1, 1993

Identification of Carbohydrate Structures in Glycoprotein Peptide Maps by the Use of LC/MS with Selected Ion Extraction with Special Reference to Tissue Plasminogen Activator and a Glycosylation Variant Produced by Site Directed Mutagenesis

Analytical Chemistry, ISSN: 15206882 00032700

Andrew W. Guzzetta; Basa; William S. Hancock; Keyt; William F. Bennett

November 1, 1993

Response to influenza infection in mice with a targeted disruption in the interferon γ gene

Journal of Experimental Medicine, ISSN: 15409538 00221007

Mary Beth Graham; Dyana K. Dalton; Giltinan; Vivian L. Braciale; Stewart; Thomas J. Braciale

October 15, 1993

Isolation and characterization of an intracellular serine proteinase inhibitor from a monkey kidney epithelial cell line

Journal of Biological Chemistry, ISSN: 00219258

Kurt A. Morgenstern; William J. Henzel; Baker; Susan C. Wong; Andrzej Pastuszyn; Walter Kisiel

October 1, 1993

Isolation and properties of a soluble sialidase from the culture fluid of chinese hamster ovary cells

Glycobiology, ISSN: 09596658

Warner; Joseph Chang; Ferrari; Reed J. Harris; McNerney; Bennett; Burnier; Mary B. Sliwkowski

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