Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14051 - 14100 OF 15583 RESULTS

Human relaxin decreases collagen accumulation in vivo in two rodent models of fibrosis
Journal of Investigative Dermatology, ISSN: 15231747 0022202X
Elaine N. Unemori; Steven Beck; Wyne P. Lee; Yvette Xu; Mark Siegel; Gilbert-Andre Keller; Liggitt; Eugene A. Bauer; Edward P. Amento
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Growth factor modulation of insulin-like growth factor-binding proteins in rat osteoblast-like cells
Endocrinology, ISSN: 19457170 00137227
Theresa L. Chen; Chang; DiGregorio; Andrew J. Perlman; Yung-Fu Huang
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Glycosylation-dependent cell adhesion molecule 1 (GlyCAM 1) mucin is expressed by lactating mammary gland epithelial cells and is present in milk
Journal of Clinical Investigation, ISSN: 00219738
Dowbenko; Kikuta; Christopher Fennie; Nancy Gillett; Lasky
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Partial functional mapping of the human interleukin-8 type A receptor: Identification of a major ligand binding domain
Journal of Biological Chemistry, ISSN: 00219258
Hébert; Anan Chuntharapai; Smith; Timothy J. Colby; Jin Kim; Richard Horuk
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Protein engineering. Editorial overview
Current Opinion in Biotechnology, ISSN: 09581669
Anthony A. Kossiakoff; Michael Smith
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Increased Transforming Growth Factor β Expression Inhibits Cell Proliferation in Vitro, yet Increases Tumorigenicity and Tumor Growth of Meth A Sarcoma Cells
Cancer Research, ISSN: 15387445 00085472
Hsun-Lang Chang; Nancy Gillett; Figari; Alfredo R. Lopez; Michael A. Palladino; Rik Derynck
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Characterization of radioiodinated recombinant human TGF‐β1 binding to bone matrix within rabbit skull defects
Journal of Bone and Mineral Research, ISSN: 15234681 08840431
Richardson; Zioncheck; Edward P. Amentoè; Leo Deguzmanè; Wyne P. Leeè; Yvette Xuè; L. Steven Beckè
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Expression of insulin-like growth factor-I (IGF-I) in the rat fallopian tube: Possible autocrine and paracrine action of fallopian tube-derived IGF-I on the fallopian tube and on the preimplantation embryo
Endocrinology, ISSN: 19457170 00137227
Carlsson; Hillensjo; Anders Nilsson; Tornell; Billig
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Activated eosinophils evoke chloride secretion in model intestinal epithelia primarily via regulated release of 5'-AMP
Journal of Immunology, ISSN: 00221767
Murray B. Resnick; Sean P. Colgan; Thomas W. Patapoff; Mrsny; Christopher S. Awtrey; Charlene Delp-Archer; Peter F. Weller; James L. Madara
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Stability and characterization of human growth hormone.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Rodney Pearlman; Bewley
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Intravenous and endobronchial administration of G4120, a cyclic Arg-Gly-Asp-containing platelet GPIIb/IIIa receptor-blocking pentapeptide, enhances and sustains coronary arterial thrombolysis with rt-PA in a canine preparation
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Tsunehiro Yasuda; Herman K. Gold; Chikashi Kohmura; Luis Guerrero; Hiroyuki Yaoita; John T. Fallon; Bunting; Desire Collen
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Assessing genetic heterogeneity in production cell lines: Detection by peptide mapping of a low level tyr to gln sequence variant in a recombinant antibody
Nature Biotechnology, ISSN: 10870156
Reed J. Harris; Amy Murnane; Utter; Karen L. Wagner; Edward T. Cox; Gian D. Polastri; Helder; Mary B. Sliwkowski
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The vascular endothelial growth factor (VEGF) isoforms: Differential deposition into the subepithelial extracellular matrix and bioactivity of extracellular matrix-bound VEGF
Molecular Biology of the Cell, ISSN: 10591524
John E. Park; Gilbert-Andre Keller; Napoleone Ferrara
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Protective effects of selectin chimeras in neutrophil-mediated lung injury
Journal of Immunology, ISSN: 00221767
Michael S. Mulligan; Susan R. Watson; Christopher Fennie; Peter A. Ward
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In situ ligand binding of recombinant human [125I] activin-A and recombinant human [125I]inhibin-A to the adult rat ovary
Endocrinology, ISSN: 19457170 00137227
Woodruff; Lynne Krummen; Glynis McCray; Mather
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Preparation of Radiolabeled Materials for Studies of Deposition of Fibers in the Human Respiratory Tract
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684
Chan; Gonda
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Humanization of an antibody directed against IgE
Journal of Immunology, ISSN: 00221767
Presta; Steven Lahr; Robert L. Shields; James P. Porter; Cornelia M. Gorman; Brian M. Fendly; Paula Jardieu
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Binding of L-selectin to the vascular sialomucin CD34
Science, ISSN: 00368075
Baumhueter; Mark S. Singer; William J. Henzel; Stefan Hemmerich; Renz; Steven D. Rosen; Lasky
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Stability characterization and formulation development of alteplase, a recombinant tissue plasminogen activator.
Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467
Tue H. Nguyen; Carole A. Ward
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Comparative analysis of the human macrophage inflammatory protein family of cytokines (chemokines) on proliferation of human myeloid progenitor cells: Interacting effects involving suppression, synergistic suppression, and blocking of suppression
Journal of Immunology, ISSN: 00221767
Hal E. Broxmeyer; Barbara Sherry; Scott Cooper; Li Lu; Rodney Maze; M. Patricia Beckmann; Cerami; Peter Ralph
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Appearance of additional ouabain binding sites on platelet surfaces following activation
Experimental Cell Research, ISSN: 00144827
Tracie Bork; Mrsny
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Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet α-granules
Journal of Clinical Investigation, ISSN: 00219738
Prem Handagama; Dorothy F. Bainton; Yvonne Jacques; Marion T. Conn; Lazarus; Shuman
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IGF-I is required for normal embryonic growth in mice
Genes and Development, ISSN: 08909369
Powell-Braxton; Hollingshead; Warburton; Mary Dowd; Sharon Pitts-Meek; Dyana K. Dalton; Nancy Gillett; Stewart
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Biosynthesis and function of membrane bound and secreted forms of recombinant CD11b/CD18 (Mac‐1)
Journal of Cellular Biochemistry, ISSN: 10974644 07302312
Berman; Nakamura; Riddle; Chiu; Karen L. Fisher; Mark Champe; Gray; Ward; Fong
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Crystal structure of a sweet tasting protein thaumatin I, at 1·65 Å resolution
Journal of Molecular Biology, ISSN: 00222836
Craig M. Ogata; Paul F. Gordon; De Vos; Sung-Hou Kim
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Identification of a single amino acid residue responsible for the binding of a class of β-adrenergic receptor antagonists to 5-hydroxytryptamine(1A) receptors
Molecular Pharmacology, ISSN: 0026895X
Xiao-Ming Guan; Peroutka; Brian K. Kobilka
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Identification of human milk α-lactalbumin as a cell growth inhibitor
Protoplasma, ISSN: 0033183X 16156102
Thompson; Farrell Jr.; Sanjeeva Mohanam; Sue Liu; Kidwell; Bansal; Cook; Medina; Claire Kotts; Mozeena Bano
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Guidelines for national authorities on quality assurance for biological products
World Health Organization - Technical Report Series, ISSN: 05123054
Ayres; Benmansour; Breschkin; Darodjatun; Drozdov; Esber; Furesz; Homma; Jeffcoate; Kalyanaraman; Langlois; Magrath; Moor; John F. Obijeski; Sizaret; Spieser; Weber; Xiang Jianzhi
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Expression and characterization of hepatocyte growth factor receptor-IgG fusion proteins. Effects of mutations in the potential proteolytic cleavage site on processing and ligand binding
Journal of Biological Chemistry, ISSN: 00219258
Melanie R Mark; Lokker; Zioncheck; Luis; Godowski
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Both intrathymic and peripheral selection modulate the differential expression of Vβ among CD4+ and CD8+ T cells
Journal of Experimental Medicine, ISSN: 15409538 00221007
Pamela J. Fink; Kathryn Swan; Gail Turk; Mark Moore; Francis R. Carbone
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Dual regulation of vascular endothelial growth factor bioavailability by genetic and proteolytic mechanisms
Journal of Biological Chemistry, ISSN: 00219258
Houck; Leung; Rowland; Jane Winer; Napoleone Ferrara
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Basis for the use of rhDNase as a therapy in cystic fibrosis
Polymeric Materials Science and Engineering, Proceedings of the ACS Division of Polymeric Materials Science and Engineering, ISSN: 07430515
Pearlman; Steven J. Shire; Cipolla; Daugherty; Thomas W. Patapoff; Ross C. Clark; Gilbert-Andre Keller; Mrsny
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RANTES and macrophage inflammatory protein lot induce the migration and activation of normal human eosinophil granulocytes
Journal of Experimental Medicine, ISSN: 15409538 00221007
Antal Rot; Martin Krieger; Thomas Brunner; Stephan C. Bischoff; Thomas J. Schall; Clemens A. Dahinden
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Synthesis and Vibrational Analysis of a Locked 14-s-cis Conformer of Retinal
Journal of the American Chemical Society, ISSN: 15205126 00027863
Mary E. M. Cromwell; Ronald Gebhard; Xiao-Yuan Li; Elvira S. Batenburg; Johan C.P. Hopman; Johan Lugtenburg; Richard A. Mathies
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The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein
Journal of Biological Chemistry, ISSN: 00219258
Leonard; Matthew J. Hart; Jill V. Platko; Alessandra Eva; William J. Henzel; Tony Evans; Richard A. Cerione
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The identification and characterization of a GDP-dissociation inhibitor (GDI) for the CDC42Hs protein
Journal of Biological Chemistry, ISSN: 00219258
David Leonard; Matthew J. Hart; Jill V. Platko; Alessandra Eva; William J. Henzel; Tony Evans; Richard A. Cerione
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Detection of human leukemia inhibitory factor by monoclonal antibody based ELISA
Journal of Immunological Methods, ISSN: 00221759
K.Jin Kim; Merlyn Alphonso; Charles H. Schmelzer; David G Lowe
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Proteins containing an uncleaved signal for glycophosphatidylinositol membrane anchor attachment are retained in a post-ER compartment
Journal of Cell Biology, ISSN: 00219525
Paul Moran; Caras
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Separation of oxidized human growth hormone variants by revesed-phase high-performance liquid chromatography. Effect of mobile phase pH and organic modifier
Journal of Chromatography A, ISSN: 00219673
Glen Teshima; Eleanor Canova-Davis
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The synthesis of chiral 3-oxo-6-[(phenylmethoxy)-carbonyl]-2-piperazineacetic acid esters designed for the presentation of an aspartic acid side chain. A subsequent novel Friedel Crafts reaction
Tetrahedron Letters, ISSN: 00404039
Timothy P. Kogan; Thomas E. Rawson
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An antibody capture bioassay (ACB) for DNase in human serum samples
Journal of Immunological Methods, ISSN: 00221759
Ursula E.M. Gibson; Chen; Baker; Sinicropi
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Identification of a soluble form of a ligand for the lymphocyte homing receptor
Journal of Experimental Medicine, ISSN: 15409538 00221007
Brustein; Kraal; Mebius; Susan R. Watson
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Structural Studies of Potent Constrained RGD Peptides
Journal of the American Chemical Society, ISSN: 15205126 00027863
Robert S. McDowell; Thomas Gadek
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Orthogonally Protected N3-(Carboxymethyl)-l-2,3-diaminopropanoic Acids and O-(Carhoxymethyl)-L-serines for Solid-Phase Peptide Synthesis
Journal of Organic Chemistry, ISSN: 15206904 00223263
Mark S. Stanley
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Precursor structure, expression, and tissue distribution of human guanylin
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Frederic J. De Sauvage; Satish Keshav; Wun-Jing Kuang; Nancy Gillett; William J. Henzel; David V. Goeddel
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Structural effects induced by mutagenesis affected by crystal packing factors: The structure of a 30–51 disulfide mutant of basic pancreatic trypsin inhibitor
Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585
Eigenbrot; Michael Randal; Anthony A. Kossiakoff
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Crystallization and preliminary characterization of three crystal forms of human recombinant transforming growth factor-α
Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X
Avis T. Danishefsky; Louis E. Burton; Rubin
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High resolution functional analysis of antibody-antigen interactions
Journal of Molecular Biology, ISSN: 00222836
Jin; Brian M. Fendly; James A. Wells
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Further characterization of the interaction between L-selectin and its endothelial ligands
Glycobiology, ISSN: 09596658
Yasuyuki Imai; Lasky; Steven D. Rosen
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The synthesis of substituted methoxypoly(ethyleneglycol) derivatives suitable for selective protein modification
Synthetic Communications, ISSN: 15322432 00397911
Timothy P. Kogan
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