Genentech: Publications

August 1, 1992

Quantitation of E. coli protein impurities in recombinant human interferon-γ

Applied Biochemistry and Biotechnology, ISSN: 02732289 15590291

Chen; Championsmith; Blanchard; Gorrell; Niepelt; Federici; Formento; Sinicropi

July 31, 1992

Ecdysteroid-dependent regulation of genes in mammalian cells by a Drosophila ecdysone receptor and chimeric transactivators

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Christopherson; Melanie R Mark; Bajaj; Godowski

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July 31, 1992

Relaxin increases rat heart rate by a direct action on the cardiac atrium

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

David G. Ward; G. Roger Thomas; Cronin

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July 6, 1992

A simple approach to improving sensitivity in a one-step monoclonal antibody-based ELISA for human IIbIIIa using multiple conjugates

Journal of Immunological Methods, ISSN: 00221759

Rowland; Michael A. Wooldridge; Rosenthal; Wai Lee T. Wong

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July 1, 1992

Gas-Phase Host-Guest Chemistry of Carcerands and Hemicarcerands

Journal of the American Chemical Society, ISSN: 15205126 00027863

Lydia M. Nuwaysir; John A. Castoro; Cathy Liub-Chii Yang; Charles L. Wilkins

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June 12, 1992

Purification, sequence, and cellular localization of a novel chromosomal protein that binds to Methylated DNA

Cell, ISSN: 00928674

Joe D. Lewis; Richard R. Meehan; William J. Henzel; Ingrid Maurer-Fogy; Peter Jeppesen; Franz Klein; Adrian Bird

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June 12, 1992

An endothelial ligand for L-Selectin is a novel mucin-like molecule

Cell, ISSN: 00928674

Lasky; Mark S. Singer; Dowbenko; Yasuyuki Imai; William J. Henzel; Christopher Grimley; Christopher Fennie; Nancy Gillett; Susan R. Watson; Steven D. Rosent

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June 4, 1992

The three members of the selectin receptor family recognize a common carbohydrate epitope, the sialyl Lewis(x) oligosaccharide

Journal of Cell Biology, ISSN: 00219525

Carroll Foxall; Susan R. Watson; Dowbenko; Christopher Fennie; Lasky; Makoto Kiso; Hasegawa; Darwin Asa; Brian K. Brandley

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June 1, 1992

Sequence of the exon-containing regions of the human factor VIII gene

Human Molecular Genetics, ISSN: 09646906

Jane Gitschier; William I. Wood

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June 1, 1992

Estrogen-dependent, tamoxifen-resistant tumorigenic growth of MCF-7 cells transfected with HER2/neu

Breast Cancer Research and Treatment, ISSN: 01676806 15737217

Benz; Gary K. Scott; Jay Sarup; Johnson; Debasish Tripathy; Ester Coronado; Shepard; C.Kent Osborne

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June 1, 1992

Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex

Molecular Endocrinology, ISSN: 19449917 08888809

Leong; Baxter; Camerato; Jin Dai; William I. Wood

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June 1, 1992

Purification and sequence determination of canine relaxin

Journal of Protein Chemistry, ISSN: 02778033 15734943

Dennis R. Stewart; William J. Henzel; Richard L. Vandlen

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June 1, 1992

Structure and functional expression of the acid-labile subunit of the insulin-like growth factor-binding protein complex

Molecular Endocrinology, ISSN: 19449917 08888809

Leong; Robert C. Baxter; Camerato; Jin Dai; William I. Wood

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May 20, 1992

Hydrogen bonding in globular proteins

Journal of Molecular Biology, ISSN: 00222836

Douglas F. Sticke; Presta; Ken A. Dill; George D. Rose

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May 1, 1992

Purification and characterization of recombinant porcine prorelaxin expressed in Escherichia coli

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

G.Kesava Reddy; Sripad Gunwar; Carla B. Green; David T.W. Fei; Chen; Simon C.M. Kwok

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May 1, 1992

A polymorphic dinucleotide repeat in intron 1 of the human tissue plasminogen activator gene

Human Molecular Genetics, ISSN: 09646906

Thomas; Drayna

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May 1, 1992

Human chromosome 19 contains the neurotrophin-5 gene locus and three related genes that may encode novel acidic neurotrophins

Somatic Cell and Molecular Genetics, ISSN: 07407750 15729931

Lucy R. Berkemeier; Tayfun Özçelik; Uta Francke; Rosenthal

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May 1, 1992

Cyclic RGD Peptide Analogues as Antiplatelet Antithrombotics

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Peter L. Barker; Sherron L. Bullens; Bunting; Burdick; Kathryn S. Chan; Tracy Deisher; Eigenbrot; Thomas Gadek; Robin Gantzos; Michael T. Lipari; Craig D. Muir; Napier; Pitti; Allan Padua; Quan; Mark S. Stanley; Martin Struble; Jeffrey Tom; Burnier

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April 30, 1992

Tumor necrosis factor-α pretreatment is protective in a rat model of myocardial ischemia-reperfusion injury

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Lynne J. Eddy; David V. Goeddel; Grace H.W. Wong

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April 24, 1992

Nerve growth factor increases calcium binding protein (Calbindin-D28K) in rat olfactory bulb

Brain Research, ISSN: 00068993

Iacopino; Christakos; Modi; C.Anthony Altar

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April 8, 1992

Recombinant Human DNase Inhalation in Normal Subjects and Patients With Cystic Fibrosis: A Phase 1 Study

JAMA - Journal of the American Medical Association, ISSN: 15383598 00987484

Moira L. Aitken; Wylie Burke; Gwen McDonald; Shak; A. Bruce Montgomery; Arnold L. Smith

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April 1, 1992

Differentiation factor/leukemia inhibitory factor protection against lethal endotoxemia in mice: Synergistic effect with interleukin 1 and tumor necrosis factor

Journal of Experimental Medicine, ISSN: 15409538 00221007

Richard Alexander; Grace H.W. Wong; Gerard M. Doherty; David J. Venzon; Douglas L. Fraker; Jeffrey A. Norton

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March 19, 1992

A preliminary study of aerosolized recombinant human deoxyribonuclease i in the treatment of cystic fibrosis

New England Journal of Medicine, ISSN: 15334406 00284793

Richard C. Hubbard; McElvaney; Birrer; Woodrow W. Robinson; Clara Jolley; Ronald G. Crystal; Shak; Margaret Wu; Milica S. Chernick

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March 6, 1992

Computer simulation as a tool for the rapid optimization of the high-performance liquid chromatogrpahic separation of a tryptic digest human growth hormone

Journal of Chromatography A, ISSN: 00219673

Chloupek; William S. Hancock; Lloyd R. Snyder

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March 1, 1992

Analysis of solvent structure in proteins using neutron D2OH2O solvent maps: Pattern of primary and secondary hydration of trypsin

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Anthony A. Kossiakoff; Sintchak; Shpungin; Presta

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February 14, 1992

Identity of a differentiation inhibiting factor for mouse myeloid leukemia cells with NM23/nucleoside diphosphate kinase

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Junko Okabe-Kado; Takashi Kasukabe; Yoshio Honma; Moriaki Hayashi; William J. Henzel; Hozumi

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February 5, 1992

The structure of human lymphotoxin (tumor necrosis factor-β) at 1.9-Å resolution

Journal of Biological Chemistry, ISSN: 00219258

Michael J. Eckt; Ultsch; Rinderknecht; De Vos; Stephen R. Sprang

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February 1, 1992

Incorporation of a Stabilizing Ca2+-Binding Loop into Subtilisin BPN

Biochemistry, ISSN: 15204995 00062960

Braxton; James A. Wells

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February 1, 1992

Mambin, a Potent Glycoprotein Ilb-IIIa Antagonist and Platelet Aggregation Inhibitor Structurally Related to the Short Neurotoxins

Biochemistry, ISSN: 15204995 00062960

Robert S. McDowell; Dennis; Michael G. Mulkerrin; Lazarus; Louie; Shuster

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February 1, 1992

Antigen Binding Thermodynamics and Antiproliferative Effects of Chimeric and Humanized anti-p185HER2 Antibody Fab Fragments

Biochemistry, ISSN: 15204995 00062960

Robert F. Kelley; Mark P. O'Connell; Paul J. Carter; Presta; Eigenbrot; Michael Covarrubias; Snedecor; James H. Bourell; David Vetterlein

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February 1, 1992

The Ca2+Ion and Membrane Binding Structure of the Gla Domain of Ca-Prothrombin Fragment 1

Biochemistry, ISSN: 15204995 00062960

Soriano-Garcia; Kaillathe Padmanabhan; Alexander Tulinsky; De Vos

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February 1, 1992

13C NMR Investigation of the Anomeric Specificity of CMP-TV-Acetylneuraminic Acid Synthetase from Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Michael G. Ambrose; Freese; Mary S. Reinhold; Williie F. Vann; Warner

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February 1, 1992

Human Natriuretic Peptide Receptor-A Guanylyl Cyclase Is Self-Associated prior to Hormone Binding

Biochemistry, ISSN: 15204995 00062960

David G Lowe

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February 1, 1992

The Type II Isoform of Bovine Brain Protein L-Isoaspartyl Methyltransferase Has an Endoplasmic Reticulum Retention Signal (…RDEL) at Its C-Terminus

Biochemistry, ISSN: 15204995 00062960

Steven M. Potter; Brett A. Johnson; Agnes Henschen; Aswad; Andrew W. Guzzetta

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February 1, 1992

Characterization of a Recombinant Extracellular Domain of the Type 1 Tumor Necrosis Factor Receptor: Evidence for Tumor Necrosis Factor-α Induced Receptor Aggregation

Biochemistry, ISSN: 15204995 00062960

Diane Pennica; Paul E. Borchardt; Lewis; David V. Goeddel; William J. Kohr; Helga Raab; Brian M. Fendly; Steven J. Shire

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February 1, 1992

Engagement of major histocompatibility complex class II molecules by superantigen induces inflammatory cytokine gene expression in human rheumatoid fibroblast-like synoviocytes

Journal of Experimental Medicine, ISSN: 15409538 00221007

Walid Mourad; Khalil Mehindate; Thomas J. Schall; Shaun R. McColl

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February 1, 1992

A Region of Tissue Plasminogen Activator That Affects Plasminogen Activation Differentially with Various Fibrin(ogen)-Related Stimulators

Biochemistry, ISSN: 15204995 00062960

Eastman; Florian M. Wurm; Robert Van Reis; Deborah L. Higgins

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January 31, 1992

A role for IGF-1 in the rescue of CNS neurons following hypoxic-ischemic injury

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Peter Gluckman; Nicolin Klempt; Jian Guan; Carina Mallard; Ernest Sirimanne; Mike Dragunow; Martin Klempt; Singh; Chris Williams; Nikolics

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January 1, 1992

Pharmacokinetic modeling for evaluating dosing strategies of anti-p185HER2 monoclonal antibodies

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings, ISSN: 1557170X

Schoenhoff; Daniel A. Maneval; Hutchins; Gregory S. Blank; David Vetterlein; Joyce Mordenti; Green

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January 1, 1992

Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis

Molecular Immunology, ISSN: 01615890

Joseph R. Weber; Nelson; Cunningham; James A. Wells; Fong

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January 1, 1992

Human seminal relaxin is a product of the same gene as human luteal relaxin

Endocrinology, ISSN: 19457170 00137227

Winslow; Shih; James H. Bourell; Gerson Weiss; Baron R. Reed; Stults; Laura T. Goldsmith

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January 1, 1992

Thyroid follicular cells produce interleukin-8

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Weetman; Bennett; Wai Lee T. Wong

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January 1, 1992

Passive immunoneutralization with a monoclonal antibody reveals a role for endogenous activin-b in mediating fsh hypersecretion during estrus and following ovariectomy of hypophysectomized, pituitary-grafted rats

Endocrinology, ISSN: 19457170 00137227

Louis V. DePaolo; Bald; Brian M. Fendly

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January 1, 1992

Vascular endothelial growth factor messenger ribonucleic acid expression in the primate ovary

Endocrinology, ISSN: 19457170 00137227

Ravindranath; Lynda Little-Ihrig; Phillips; Napoleone Ferrara; Anthony J. Zeleznik

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January 1, 1992

Recovery of Cholinergic Phenotype in the Injured Rat Neostriatum: Roles for Endogenous and Exogenous Nerve Growth Factor

Journal of Neurochemistry, ISSN: 14714159 00223042

C.Anthony Altar; Armanini; Dugich-Djordjevic; Bennett; Regina Williams; Shamiram Feinglass; Vincent R. Anicetti; Sinicropi; Bakhit

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January 1, 1992

Activity and Biospecificity of Proteolyzed Forms and Dimeric Combinations of Recombinant Human and Murine Nerve Growth Factor

Journal of Neurochemistry, ISSN: 14714159 00223042

Louis E. Burton; Charles H. Schmelzer; Szonyi; Yedinak; Gorrell

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January 1, 1992

High resolution removal of virus from protein solutions using a membrane of unique structure

Bio/Technology, ISSN: 0733222X

Anthony J. DiLeo; Anthony E. Allegrezza Jr.; Stuart E. Builder

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January 1, 1992

DnaK-Mediated alterations in human growth hormone protein inclusion bodies

Bio/Technology, ISSN: 0733222X

Paul Blum; Mark Velligan; Lin; Abdul Matin

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January 1, 1992

Polyethylene glycol enhanced protein refolding

Bio/Technology, ISSN: 0733222X

Cleland; Stuart E. Builder; James R. Swartz; Maijorie Winkler; Judy H. Chang; Daniel I. C. Wang

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January 1, 1992

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

Science, ISSN: 00368075

Carlie De Vries; Escobedo; Hikaru Ueno; Houck; Napoleone Ferrara; Williams

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