Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14951 - 15000 OF 15632 RESULTS

January 1, 1989

Inflammatory destruction of pancreatic β cells in γ-interferon transgenic mice

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Sarvetnick; Shizuru; Liggitt; Stewart

January 1, 1989

1H NMR Structural Characterization of a Recombinant Kringle 2 Domain from Human Tissue-Type Plasminogen Activator

Biochemistry, ISSN: 15204995 00062960

In-Ja L. Byeon; Robert F. Kelley; Miguel Llinás

January 1, 1989

Endothelial interleukin-8: A novel inhibitor of leukocyte-endothelial interactions

Science, ISSN: 00368075

Gimbrone Jr.; Obin; Brock; Luis; Hass; Hébert; Yip; Leung; Lowe; William J. Kohr; Darbonne; Bechtol; Baker

January 1, 1989

Engineering subtilisin BPN′ for site‐specific proteolysis

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Paul J. Carter; Björn Nilsson; Burnier; Burdick; James A. Wells

January 1, 1989

A common language for physical mapping of the human genome

Science, ISSN: 00368075

Maynard Olson; Leroy Hood; Charles Cantor; David Botstein

January 1, 1989

A fusion protein required for vesicle-mediated transport in both mammalian cells and yeast

Nature, ISSN: 00280836

Duncan W. Wilson; Celeste A. Wilcox; Gregory C. Flynn; Ellson Y. Chen; Wun-Jing Kuang; William J. Henzel; Marc R. Block; Axel Ullrich; James E. Rothman

January 1, 1989

Cloning and expression of the cDNA for the murine interferon γ receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Patrick W. Gray; Leong; Fennie; Farrar; Pingel; Fernandez-Luna; Schreiber

January 1, 1989

Synthesis of novel polycyclic nucleoside analogues incorporation into oligodeoxynucleotides, and interaction with complementary sequences

Journal of the American Chemical Society, ISSN: 15205126 00027863

Norbert Bischofberger; Matteucci

January 1, 1989

Monoclonal Antibodies: Production, Purification, and Technology

Advances in Clinical Chemistry, ISSN: 00652423

David Vetterlein

January 1, 1989

Pharmacologic basis for the safety assessment of recombinant human proteins

Journal of the American College of Toxicology, ISSN: 07300913

Cossum

January 1, 1989

Peptide-based radioimmunoassay for insulin receptor. Detection of insulin-stimulated downregulation in IM-9 lymphocytes

Diabetes, ISSN: 00121797

McFarland; Ramachandran; Grunfeld

January 1, 1989

Fibroblasts transformed with v-src show enhanced formation of an inositol tetrakisphosphate

Science, ISSN: 00368075

Johnson; Wasilenko; Matringly; Weber; Garrison

January 1, 1989

Designing CD4 immunoadhesins for AIDS therapy

Nature, ISSN: 00280836

Capon; Steven M. Chamow; Joyce Mordenti; Scot A. Marsters; Timothy Gregory; Hiroaki Mitsuya; Randal A. Byrn; Catherine Lucas; Florian M. Wurm; Jerome E. Groopman; Samuel Broder; Smith

January 1, 1989

Studies of the HER-2/neu proto-oncogene in human breast and ovarian cancer

Science, ISSN: 00368075

Dennis J. Slamon; William Godolphin; Lovell A. Jones; John A. Holt; Steven Wong; Duane E. Keith; Wendy J. Levin; Susan G. Stuart; Judy Udove; Axel Ullrich; Michael F. Press

January 1, 1989

Protein Engineering of Disulfide Bonds in Subtilisin BPN'

Biochemistry, ISSN: 15204995 00062960

Colin Mitchinson; James A. Wells

January 1, 1989

Human transforming growth factor-β3: Recombinant expression, purification, and biological activities in comparison with transforming growth factors-β1 and -β2

Molecular Endocrinology, ISSN: 19449917 08888809

Graycar; Duncan A. Miller; Arrick; Lyons; Moses; Rik Derynck

January 1, 1989

The MHC-binding and gpl20-binding functions of CD4 are separable

Science, ISSN: 00368075

Daniel Lamarre; Avi Ashkenazi; Sylvain Fleury; Smith; Rafick-P. Sekaly; Capon

January 1, 1989

Purification and Characterization of Tissue Plasminogen Activator Kringle-2 Domain Expressed in Escherichia coli

Biochemistry, ISSN: 15204995 00062960

Scott Cleary; Michael G. Mulkerrin; Robert F. Kelley

January 1, 1989

Generic trans-kingdom sex?

Nature, ISSN: 00280836

Scott E. Stachel; Patricia C. Zambryski

January 1, 1989

Fragments of Bovine Insulin-like Growth Factors I and II Stimulate Proliferation of Rat L6 Myoblast Cells

Biochemistry, ISSN: 15204995 00062960

Yasuo Konishi; Claire Kotts; Lea Doerr Bullock; Jacob S. Tou; Debra A. Johnson

January 1, 1989

Purification of Recombinant Human Tissue Factor

Biochemistry, ISSN: 15204995 00062960

Lisa R. Paborsky; Keri M. Tate; Reed J. Harris; Yansura; Louise Band; Glynis McCray; Cornelia M. Gorman; Donogh P. O'Brien; Judy H. Chang; James R. Swartz; Victor P. Fung; James N. Thomas; Gordon A. Vehar

January 1, 1989

Rapid Kinetics of α2-Adrenergic Inhibition of Adenylate Cyclase. Evidence for a Distal Rate-Limiting Step

Biochemistry, ISSN: 15204995 00062960

William J. Thomsen; Richard R. Neubig

January 1, 1989

Lutropin-choriogonadotropin receptor: An unusual member of the G protein-coupled receptor family

Science, ISSN: 00368075

McFarland; Rolf Sprengel; Phillips; Martin Köhler; Nora Rosemblit; Nikolics; Deborah L. Segaloff; Peter H. Seeburg

January 1, 1989

Connective tissue metabolism including cytokines

Current Opinion in Rheumatology, ISSN: 10408711

Edward P. Amento

January 1, 1989

Substrate Specificities of Growth Factor Associated Kallikreins of the Mouse Submandibular Gland

Biochemistry, ISSN: 15204995 00062960

Michael Blaber; Paul J. Isackson; James C. Marsters Jr.; Burnier; Ralph A. Bradshaw

January 1, 1989

Absorption of human growth hormone from the rat lung.

Biotechnology Therapeutics, ISSN: 08982848

John R. Patton; McCabe; Hansen; Daugherty

January 1, 1989

A yeast actin-binding protein is encoded by SAC6, a gene found by suppression of an actin mutation

Science, ISSN: 00368075

Alison E. M. Adams; David Botstein; Drubin

December 8, 1988

Thrombolytic Therapy

New England Journal of Medicine, ISSN: 15334406 00284793

Grossbard; Chesebro; Knatterud; Eugene Braunwald; Ross; Simoons; Verstraete; Stephen Gerard; Jack Levin; Runge; Haber; Marder; Sherry

December 1, 1988

Design objectives for aseptic seals

Wisniewski

December 1, 1988

Treatment strategies after successful thrombolysis in acute myocardial infarction

Heart and Lung: Journal of Acute and Critical Care, ISSN: 01479563

Ramsden

December 1, 1988

Cloning and mRNA tissue distribution of rabbit cholesteryl ester transfer protein

Journal of Lipid Research, ISSN: 00222275

Mariko Nagashima; McLean; Lawn

December 1, 1988

The Role of Quality Control in Biotechnology: An Analytical Perspective

Analytical Chemistry, ISSN: 15206882 00032700

Robert L. Garnick; Solli; Papa

December 1, 1988

Human tumor necrosis factor-α receptor. Purification by immunoaffinity chromatography and initial characterization

Journal of Biological Chemistry, ISSN: 00219258

Stauber; Aiyer; Aggarwal

December 1, 1988

Assessment of successful reperfusion after thrombolysis

Heart and Lung: Journal of Acute and Critical Care, ISSN: 01479563

Henderson

November 11, 1988

Sequence of the Bacillus thuringiensis phosphatidylinositol specific phospholipase C

Nucleic Acids Research, ISSN: 03051048

Henner; Yang; Ellson Y. Chen; Renate Hellmiss; Rodriguez; Martin G. Low

November 1, 1988

Inhibitors of Cyclic AMP Phosphodiesterase. 3. Synthesis and Biological Evaluation of Pyrido and Imidazolyl Analogues of 1,2,3,5-Tetrahydro-2-oxoimidazo[2,1-b]quinazoline

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Robert A. Stephenson; Robert Alvarez; John J. Bruno; Arthur M. Strosberg

November 1, 1988

Topical Nonsteroidal Antipsoriatic Agents. 2. 2,3-(Alkylidenedioxy)naphthalene Analogues of Lonapalene

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Brad E. Loe; Gordon H. Jones; John M. Young

November 1, 1988

Inhibitors of Cyclic AMP Phosphodiesterase. 4. Synthesis and Evaluation of Potential Prodrugs of Lixazinone (N-Cyclohexyl-N-methyl-4-[(1,2,3,5-tetrahydro-2-oxoimidazo[2,1-b]quinazolin-7-yl)-oxy]butyramide, RS-82856)

Journal of Medicinal Chemistry, ISSN: 15204804 00222623

Michael C. Venuti; Robert Alvarez; John J. Bruno; Arthur M. Strosberg; Leo Gu; Hi-Shi Chiang; Ian J. Massey; Nancy Chu; John H. Fried

October 4, 1988

Enzyme-linked immunosorbent assays (ELISAs) for the determination of contaminants resulting from the immunoaffinity purification of recombinant proteins

Journal of Immunological Methods, ISSN: 00221759

Catherine Lucas; Nelson; Peterson; Frie; David Vetterlein; Timothy Gregory; Chen

September 30, 1988

Analysis of nucleotide sequences of two ligninase cDNAs from a white-rot filamentous fungus, Phanerochaete chrysosporium

Gene, ISSN: 03781119

Herman A. de Boer; Zhang; Collins; C.Adinarayana Reddy

September 26, 1988

The nucleotide sequence for the cDNA of bovine interleukin-1 beta

Nucleic Acids Research, ISSN: 03051048

Leong; Gail W. Flaggs; Lawman; Patrick W. Gray

September 26, 1988

The nucleotide sequence for the cDNA of bovine interleukin-1 alpha

Nucleic Acids Research, ISSN: 03051048

Leong; Gail W. Flaggs; Lawman; Patrick W. Gray

September 1, 1988

Resistance of tumor cells to tumor necrosis factor

Journal of Clinical Immunology, ISSN: 02719142 15732592

Shepard; Gail D. Lewis

August 26, 1988

Transforming growth factor α

Cell, ISSN: 00928674

Rik Derynck

August 26, 1988

Mutation of the insulin receptor at tyrosine 960 inhibits signal transmission but does not affect its tyrosine kinase activity

Cell, ISSN: 00928674

Morris F. White; James N. Livingston; Jonathan M. Backer; Vilma Lauris; Dull; Axel Ullrich; C. Ronald Kahn

August 17, 1988

Transplantation resistance to a rous sarcoma virus-induced tumor in mice immunized with v-src protein

Journal of the National Cancer Institute, ISSN: 00278874

Noboru Kuzumaki; Hisakazu Fujita; Hirotoshi Dosaka; Motoo Katabami; Levinson

August 15, 1988

Purification and characterization of the restriction endonuclease RsrI, an isoschizomer of EcoRI

Gene, ISSN: 03781119

Patricia J. Greene; Barry T. Ballard; Frank Stephenson; William J. Kohr; Rodriguez; John M. Rosenberg; Herbert W. Boyer

August 12, 1988

Analysis of host-virus interactions in AIDS with anti-gp120 T cell clones: Effect of HIV sequence variation and a mechanism for CD4+ cell depletion

Cell, ISSN: 00928674

Robert F. Siliciano; Trebor Lawton; Cindy Knall; Robert W. Karr; Berman; Timothy Gregory; Ellis L. Reinherz

August 1, 1988

ANALYTICAL AND PROCESS CHROMATOGRAPHY IN PHARMACEUTICAL PROTEIN PRODUCTION.

Chemical Engineering Progress, ISSN: 03607275

Stuart E. Builder; William S. Hancock

August 1, 1988

Tolerance and efficacy of recombinant human interferon gamma in the treatment of refractory genital warts

American Journal of Medicine, ISSN: 00029343

Philip K. Kirby; Nancy Kiviat; Ann Beckman; Denise Wells; Stephen A. Sherwin; Lawrence Corey

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