Back

Featured Topics

Behind The Science
Breast Cancer
Cancer Immunotherapy
Hematology
Lung Cancer
Manufacturing
Multiple Sclerosis
Oncology
Ophthalmology
Partnering
Respiratory Health
Rheumatology
About Us Contact Us Leadership Awards & Recognition Investors Suppliers Compliance
  • Twitter
  • Facebook
  • LinkedIn

Understanding Lupus Nephritis


Read More Stories
Nov 6, 2019

Lupus nephritis is a severe and potentially life-threatening complication of systemic lupus erythematosus (SLE) resulting from inflammation in the kidney.

~1.5 MILLION AMERICANS

are affected by lupus, and about 70% have the systemic form, SLE.1,2

Up to 60%

with SLE will develop lupus nephritis.3

Lupus nephritis overwhelmingly impacts women

particularly young women of color.2,4

It is more prevalent in certain populations.

African American, Hispanic, Native American, and Asian American women are 2 to 3 times more likely than Caucasian women to get lupus.2,4

Asian, African Caribbean, African American, and Hispanic

ethnicities are most likely to present with more severe lupus nephritis than other ethnic groups.3

Up to 25% of proliferative lupus nephritis patients will develop potentially life-threatening end-stage renal disease.5

Lupus nephritis develops early in the course of SLE, therefore becoming a major predictor of poor prognosis.5

We're taking action to recruit a broader, more diverse population of participants into clinical trials, including diseases such as lupus nephritis, to ensure clinical trial participants more closely reflect those impacted by the disease for which a medicine is being studied. To learn more about our efforts in this area, please visit http://www.gene.com/inclusiveresearch.

  •   References Down arrow

    1A. de Zubiria Salgado and C. Herrera-Diaz, "Lupus Nephritis: An Overview of Recent Findings. Autoimmune Diseases," vol. 2012, Article ID 849684, 221 pages, 2012. doi:10.1155/2012/849684

    2Lupus Facts and Statistics. Last accessed October 24, 2019
    Available at: https://www.lupus.org/resources/lupus-facts-and-statistics

    3Ramesh Saxena, Tina Mahaian and Chandra Mohan, "Lupus Nephritis: Current Update," Arthritis Research & Therapy, 2011, 13:240. doi:10.1186/ar3378

    4Lupus Research Alliance. Lupus Fact Sheet. Last accessed October 24, 2019
    Available at: http://www.lupusresearch.org/wp-content/uploads/2017/09/Lupus-Fact-Sheet.pdf

    5Alberto de Zubiria Salgado and Catalina Herrera-Diaz, "Lupus Nephritis: An Overview of Recent Findings," Autoimmune Diseases, vol. 2012, Article ID 849684, 21 pages, 2012. doi:10.1155/2012/849684


Tags:

  • Rheumatology,
  • Nephrology

Read More Stories

Read about breakthrough science, the everyday people who make it happen, and the patients we serve.

  • Now Hiring
  • Find A Job
  • Professional Areas
  • Diversity & Inclusion
  • Chief Diversity Officer
  • Fostering Belonging
  • Health Equity
  • Advancing Inclusive Research
  • Transforming Society
  • Our 2021 Diversity & Inclusion Report
  • Our Work in Action
  • Kindergarten to Careers
  • For Scientists
  • Our Scientists
  • Publications
  • Oncology
  • Immunology
  • Neuroscience
  • Metabolism
  • Infectious Disease
  • Ophthalmology
  • For Patients
  • Our Medicines
  • Financial Support
  • Genentech Patient Foundation
  • Understanding Insurance
  • Medicine Information Support
  • Clinical Trial Information
  • Advancing Inclusive Research
  • Our Approach to Pricing
  • Patient Advocacy
  • Create With Us
  • Disease Education
  • For Medical Professionals
  • Our Medicines & Products
  • Our Pipeline
  • Medical Resources
  • Clinical Trial Information
  • Sunshine Act Compliance
  • Product Security
  • For Partners
  • Our Approach
  • What We Are Looking For
  • Partner With Us
  • Our Stories
  • For Media
  • News Features
  • Press Releases
  • Statements
  • Company Information
  • Sign Up For News Alerts
  • For Good
  • Giving
  • Diversity & Inclusion
  • Sustainability
  • About Us
  • Leadership
  • Policy & Advocacy
  • Our Focus on Oncology
  • Awards & Recognition
  • Investors
  • Suppliers
  • Our Approach to Pricing
  • CA Transparency in Supply
  • Compliance Overview
  • Contact Us
  • Call Us
  • Email Us
  • Visit us
  • Submit a Medical Inquiry
  • Submit a Media Inquiry
  • —
  • Privacy Policy
  • Terms & Conditions
  • Accessibility
© 2023 Genentech, Inc. All rights reserved. This site is intended for US residents only.