Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 4751 - 4800 OF 15191 RESULTS

Treatment with a human recombinant monoclonal IgG antibody against oxidized LDL in atherosclerosis-prone pigs reduces cathepsin S in coronary lesions
International Journal of Cardiology, ISSN: 18741754 01675273
Christian Bo Poulsen; Ahmed Ludvigsen Al-Mashhadi; Karin von Wachenfeldt; Jacob Fog Bentzon; Lars Bo Nielsen; Rozh H. Al-Mashhadi; Jesper Thygesen; Lars Tolbod; Jens Rolighed Larsen; Jørgen Frøkiær; Ahmed Tawakol; Esad Vucic; Jill Fredrickson; Amos Baruch; Björn Frendéus; Anna-Karin Robertson; Søren Kragh Moestrup; Ludovic Drouet; Erling Falk
View on Scopus
A simple and sensitive method to analyze genotoxic impurity hydrazine in pharmaceutical materials
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Jennifer Wang; Samuel H. Yang; Kelly Zhang
View on Scopus
Validation and determination of taselisib, a β-sparing phosphoinositide 3-kinase (PI3K) inhibitor, in human plasma by LC-MS/MS
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 1873264X 07317085
Xiao Ding; Faber; Shi; McKnight; Dorshorst; Joseph A. Ware; Brian J. Dean
View on Scopus
A sensitive mutation screening method supporting cell line development for biotherapeutics
Analytical Biochemistry, ISSN: 10960309 00032697
Ildana Valisheva; Reed J. Harris; Judith Zhu-Shimoni
View on Scopus
Green Chemistry Articles of Interest to the Pharmaceutical Industry
Organic Process Research and Development, ISSN: 1520586X 10836160
Rakeshwar Bandichhor; Apurba Bhattacharya; Marian C. Bryan; Andrew Cosbie; Alba Díaz-Rodríguez; Louis Diorazio; Zhongbo Fei; Kenneth Fraunhoffer; John Hayler; Matthew Hickey; Luke Humphreys; Paul Richardson; Scott Roberts; Timothy White; Stijn Wuyts; Jingjun Yin
View on Scopus
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
PLoS Biology, ISSN: 15449173
Mario Novkovic; Lucas Onder; Jovana Cupovic; Jun Abe; David Bomze; Viviana Cremasco; Elke Scandella; Jens V. Stein; Gennady Bocharov; ShannonJ. Turley; Burkhard Ludewig
View on Scopus
Topological Small-World Organization of the Fibroblastic Reticular Cell Network Determines Lymph Node Functionality
PLoS Biology, ISSN: 15457885 15449173
Mario Novkovic; Lucas Onder; Jovana Cupovic; Jun Abe; David Bomze; Viviana Cremasco; Elke Scandella; Jens V. Stein; Gennady Bocharov; Shannon J. Turley; Burkhard Ludewig
View on Scopus
Modeling and simulation of maintenance treatment in first-line non-small cell lung cancer with external validation
BMC Cancer, ISSN: 14712407
Kelong Han; Laurent Claret; Alan Sandler; Asha Das; Jin Y. Jin; Rene Bruno
View on Scopus
The selective estrogen receptor downregulator GDC-0810 is efficacious in diverse models of ER+ breast cancer
eLife, ISSN: 2050084X
James D. Joseph; Beatrice Darimont; Wei Zhou; Alfonso Arrazate; Amy Young; Ellen Ingalla; Kimberly Walter; Robert A. Blake; Jim Nonomiya; Zhengyu Guan; Kategaya; Steven P. Govek; Andiliy G. Lai; Mehmet Kahraman; Dan Brigham; John Sensintaffar; Nhin Lu; Gang Shao; Jing Qian; Kate Grillot; Michael Moon; Rene Prudente; Eric Bischoff; Kyoung-Jin Lee; Celine Bonnefous; Karensa L. Douglas; Jackaline D. Julien; Johnny Y. Nagasawa; Anna Aparicio; Josh Kaufman; Benjamin Haley; Jennifer M. Giltnane; Ingrid E. Wertz; Lackner; Michelle Nannini; Deepak Sampath; Luis J. Schwarz; H. Charles Manning; Mohammed Noor Tantawy; Carlos L. Arteaga; Richard A. Heyman; Peter J. Rix; Lori S. Friedman; Nicholas D. Smith; Ciara Metcalfe; Jeffrey H. Hager
View on Scopus
GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 10916490 00278424
Robin A. Aglietti; Alberto Estevez; Aaron Gupta; Monica Gonzalez Ramirez; Peter S. Liu; Nobuhiko Kayagaki; Claudio Ciferri; Vishva M. Dixit; Erin C. Dueber
View on Scopus
NeuCode Proteomics Reveals Bap1 Regulation of Metabolism
Cell Reports, ISSN: 22111247
Joshua M. Baughman; Christopher M. Rose; Ganesh Kolumam; Webster; Emily M. Wilkerson; Anna E Merrill; Timothy W. Rhoads; Rajkumar Noubade; Paula Katavolos; Justin Lesch; Donald S. Stapleton; Mary E. Rabaglia; Kathy L. Schueler; Raymond Asuncion; Melanie Domeyer; Jose Zavala-Solorio; Michael Reich; Jason Devoss; Mark P. Keller; Alan D. Attie; Alexander S. Hebert; Michael S. Westphall; Joshua J Coon; Donald S. Kirkpatrick; Anwesha Dey
View on Scopus
Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains
Molecular Cell, ISSN: 10974164 10972765
Till Maurer; Ingrid E. Wertz
View on Scopus
Preclinical pharmacokinetics of MHAA4549A, a human monoclonal antibody to influenza A virus, and the prediction of its efficacious clinical dose for the treatment of patients hospitalized with influenza A
mAbs, ISSN: 19420870 19420862
Priyanka Gupta; Amrita Kamath; Summer Park; Chiu; Jeff Lutman; Mauricio Maia; Man-Wah Tan; Min Xu; Lee R. Swem; Rong Deng
View on Scopus
Immunomodulatory antibodies for the treatment of lymphoma: Report on the CALYM Workshop
OncoImmunology, ISSN: 2162402X 21624011
Roch Houot; Philippe Gaulard; Schreiber; Ira Mellman; Olivier Lambotte; Pierre G. Coulie; Thierry Fest; Alan Korman; Ronald Levy; Margaret A. Shipp; Karin Tarte; Holbrook E. K. Kohrt; Aurélien Marabelle; Stephen Ansell; Hervé Watier; Andrea van Elsas; Arun Balakumaran; Frederick Arce Vargas; Sergio A. Quezada; Gilles Salles; Daniel Olive
View on Scopus
An inhibitor of KDM5 demethylases reduces survival of drug-tolerant cancer cells
Nature Chemical Biology, ISSN: 15524469 15524450
Maia Vinogradova; Victor S Gehling; Amy Gustafson; Shilpi Arora; Charles Tindell; Catherine Wilson; Kaylyn E Williamson; Gulfem D. Guler; Pranoti Gangurde; Wanda Manieri; Jennifer Busby; E. Megan Flynn; Fei Lan; Hyo-Jin Kim; Shobu Odate; Andrea G Cochran; Yichin Liu; Matthew Wongchenko; Yibin Yang; Tommy K. Cheung; Tobias Maile; Ted Lau; Michael Costa; Ganapati V. Hegde; Erica L. Jackson; Pitti; David Arnott; Christopher Bailey; Steve Bellon; Richard T Cummings; Brian K Albrecht; Jean-Christophe Harmange; James R. Kiefer; Patrick Trojer; Marie Classon
View on Scopus
A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor on the pharmacokinetics of vismodegib
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Vikram Malhi; Dawn Colburn; Sarah Williams; Cornelis E. Hop; Mark J. Dresser; Priya Chandra; Richard A. Graham
View on Scopus
Mechanism-Based Competitive Binding Model to Investigate the Effect of Neonatal Fc Receptor Binding Affinity on the Pharmacokinetic of Humanized Anti-VEGF Monoclonal IgG1 Antibody in Cynomolgus Monkey
AAPS Journal, ISSN: 15507416
Chee Ng; Fielder; Jin Y. Jin; Rong Deng
View on Scopus
A role for FOXO1 in BCR-ABL1-independent tyrosine kinase inhibitor resistance in chronic myeloid leukemia
Leukemia, ISSN: 14765551 08876924
Marie-Claire Wagle; Eiring; Matthew Wongchenko; Shan Lu; Yinghui Guan; Wang; Lackner; Lukas Amler; Garret M. Hampton; Deininger; O'Hare; Yibing Yan
View on Scopus
Implementation of mechanism of action biology-driven early drug development for children with cancer
European Journal of Cancer, ISSN: 18790852 09598049
Andy Pearson; Ralf Herold; Raphaël F. Rousseau; Chris Copland; Brigid Bradley-Garelik; Debbie Binner; Renaud Capdeville; Hubert Caron; Jacqueline Carleer; Louis Chesler; Birgit Geoerger; Pamela Kearns; Lynley V. Marshall; Stefan M. Pfister; Gudrun Schleiermacher; Jeffrey Skolnik; Cesare Spadoni; Jaroslav Sterba; Hendrick Van Den Berg; Martina Uttenreuther-Fischer; Olaf Witt; Koen Norga; Gilles Vassal; Georger; Iannone; Jakacki; Russo
View on Scopus
The Impact of Systemic Factors on Clinical Response to Ranibizumab for Diabetic Macular Edema Presented in part at: 38th Macula Society Annual Meeting, February 2015, Scottsdale, Arizona.
Ophthalmology, ISSN: 15494713 01616420
Rishi Singh; Karishma Habbu; Justis P. Ehlers; M. Cecilia Lansang; Lauren Hill; Ivaylo Stoilov
View on Scopus
Native MS and ECD Characterization of a Fab–Antigen Complex May Facilitate Crystallization for X-ray Diffraction
Journal of the American Society for Mass Spectrometry, ISSN: 18791123 10440305
Ying Zhang; Weidong Cui; Aaron T. Wecksler; Hao Zhang; Patricia Molina; Galahad Deperalta; Michael L. Gross
View on Scopus
Evaluation of Heavy-Chain C-Terminal Deletion on Product Quality and Pharmacokinetics of Monoclonal Antibodies
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Guoying Jiang; X. Christopher Yu; Daniela Bumbaca; Zhilan Hu; Annamarie Amurao; Duenas; Marc Wong; Iverson; Kai Zheng; Lam; Jia Chen; Roxanne Vega; Sheila Ulufatu; Cecilia Leddy; Helen Davis; Amy Shen; Wong; Reed J. Harris; Y. John Wang; Dongwei Li
View on Scopus
Engineering highly potent and selective microproteins against Nav1.7 sodium channel for treatment of pain
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Anatoly Shcherbatko; Andrea Rossi; Davide Foletti; Guoyun Zhu; Oren Bogin; Meritxell Galindo Casas; Mathias Rickert; Adela Hasa-Moreno; Victor Bartsevich; Andreas Crameri; Alexander R. Steiner; Robert A. Henningsen; Avinash Gill; Jaume Pons; David L. Shelton; Arvind Rajpal; Pavel Strop
View on Scopus
Uncovering a dual regulatory role for caspases during endoplasmic reticulum stress-induced cell death
Molecular and Cellular Proteomics, ISSN: 15359484 15359476
Veronica G. Anania; Kebing Yu; Florian Gnad; Rebecca R. Pferdehirt; Han Li; Taylur P. Ma; Diana Jeon; Nikolaus Fortelny; William F. Forrest; Avi Ashkenazi; Christopher Overall; Jennie R. Lill
View on Scopus
Quantitative comparison of DNA methylation assays for biomarker development and clinical applications
Nature Biotechnology, ISSN: 15461696 10870156
Christoph Bock; Florian Halbritter; Francisco J. Carmona; Sascha Tierling; Paul Datlinger; Yassen Assenov; María Berdasco; Anke K. Bergmann; Keith Booher; Florence Busato; Mihaela Campan; Christina Dahl; Christina M. Dahmcke; Dinh Diep; Agustín F. Fernández; Clarissa Gerhauser; Andrea Haake; Katharina Heilmann; Thomas Holcomb; Dianna Hussmann; Mitsuteru Ito; Ruth Kläver; Martin Kreutz; Marta Kulis; Virginia Lopez; Shalima S. Nair; Dirk S. Paul; Nongluk Plongthongkum; Wenjia Qu; Ana C. Queirós; Frank Reinicke; Guido Sauter; Thorsten Schlomm; Aaron Statham; Clare Stirzaker; Ruslan Strogantsev; Rocío G. Urdinguio; Kimberly Walter; Dieter Weichenhan; Daniel J. Weisenberger; Beck; Susan J. Clark; Manel Esteller; Anne C. Ferguson-Smith; Mario F. Fraga; Per Guldberg; Lise Lotte Hansen; Peter W. Laird; José I. Martín-Subero; Anders O. H. Nygren; Ralf Peist; Christoph Plass; David S. Shames; Reiner Siebert; Xueguang Sun; Jörg Tost; Jörn Walter; Kun Zhang
View on Scopus
Simulations to Predict Clinical Trial Outcome of Bevacizumab Plus Chemotherapy vs. Chemotherapy Alone in Patients With First-Line Gastric Cancer and Elevated Plasma VEGF-A
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kelong Han; Laurent Claret; Piao; Priti Hegde; Amita Joshi; Powell; Jin Y. Jin; Rene Bruno
View on Scopus
Quantitative phosphoproteomic analysis of the PI3K-regulated signaling network
Proteomics, ISSN: 16159861 16159853
Florian Gnad; Jeffery J. Wallin; Kyle A. Edgar; Sophia Doll; David Arnott; Liliane Robillard; Donald S. Kirkpatrick; Matthew P. Stokes; Ulka Vijapurkar; Georgia Hatzivassiliou; Lori S. Friedman; Marcia Belvin
View on Scopus
Phosphoproteome analysis of the MAPK pathway reveals previously undetected feedback mechanisms
Proteomics, ISSN: 16159861 16159853
Florian Gnad; Sophia Doll; Kyung Song; Matthew P. Stokes; John Moffat; Bonnie Liu; David Arnott; Jeffery J. Wallin; Lori S. Friedman; Georgia Hatzivassiliou; Marcia Belvin
View on Scopus
Cellular Interrogation: Exploiting Cell-to-Cell Variability to Discriminate Regulatory Mechanisms in Oscillatory Signalling
PLoS Computational Biology, ISSN: 15537358 1553734X
Javier Estrada; Natalie Andrew; Daniel Gibson; Frederick Chang; Florian Gnad; Jeremy Gunawardena
View on Scopus
Reply
Gastroenterology, ISSN: 15280012 00165085
Mary E. Keir; Tew; Jason A. Hackney
View on Scopus
Preclinical safety profile of a depleting antibody against CRTh2 for asthma: Well tolerated despite unexpected CRTh2 expression on vascular pericytes in the central nervous system and gastric mucosa
Toxicological Sciences, ISSN: 10960929 10966080
Kathila S. Rajapaksa; Tao Huang; Neeraj Sharma; Shannon Liu; Margaret Solon; Arthur Reyes; Sarah Paul; Angie Yee; Janet Tao; Sreedevi Chalasani; Nga Bien-Ly; Kai H. Barck; Richard A. D. Carano; Jianyong Wang; Linda Rangell; Meire C. Bremer; Dimitry Danilenko; Paula Katavolos; Isidro Hötzel; Karin Reif; Cary D. Austin
View on Scopus
A spectral method for color quantitation of a protein drug solution
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124 10797440
Trevor E. Swartz; Jian Yin; Thomas W. Patapoff; Travis A. Horst; Susan M. Skieresz; Gordon Leggett; Charles Morgan; Kimia Rahimi; Joseph C. Marhoul; Bruce Kabakoff
View on Scopus
Hydrolysis of polysorbate 20 and 80 by a range of carboxylester hydrolases
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124 10797440
Andrew C. McShan; Pervina Kei; Junyan A. Ji; Daniel C. Kim; Y. John Wang
View on Scopus
Validation of a spectral method for quantitative measurement of color in protein drug solutions
PDA Journal of Pharmaceutical Science and Technology, ISSN: 19482124 10797440
Jian Yin; Trevor E. Swartz; Jian Zhang; Thomas W. Patapoff; Bartolo Chen; Joseph C. Marhoul; Norman Shih; Bruce Kabakoff; Kimia Rahimi
View on Scopus
Protective and detrimental effects of neuroectodermal cell–derived tissue factor in mouse models of stroke
JCI insight,
Shaobin Wang; Brandi Reeves; Erica Sparkenbaugh; Janice Russell; Zbigniew Soltys; Hua Zhang; James E. Faber; Nigel S. Key; Daniel Kirchhofer; D. Neil Granger; Nigel Mackman; Rafal Pawlinski
View on Scopus
Protective and detrimental effects of neuroectodermal cell–derived tissue factor in mouse models of stroke
JCI insight, ISSN: 23793708
Shaobin Wang; Brandi Reeves; Erica Sparkenbaugh; Janice Russell; Zbigniew Soltys; Hua Zhang; James E. Faber; Nigel S. Key; Daniel Kirchhofer; D. Neil Granger; Nigel Mackman; Rafal Pawlinski
View on Scopus
Safety and efficacy of subcutaneous tocilizumab in adults with systemic sclerosis (faSScinate): a phase 2, randomised, controlled trial
The Lancet, ISSN: 1474547X 01406736
Dinesh Khanna; Christopher P. Denton; Angelika Jahreis; Jacob M. Van Laar; Tracy M. Frech; Marina E. Anderson; Murray Baron; Lorinda Chung; Gerhard Fierlbeck; Santhanam Lakshminarayanan; Yannick Allanore; Janet E. Pope; Gabriela Riemekasten; Virginia D. Steen; Ulf Müller-Ladner; Robert Lafyatis; Giuseppina Stifano; Helen Spotswood; Haiyin Chen-Harris; Sebastian Dziadek; Alyssa M. Morimoto; Thierry Sornasse; Jeffrey N. Siegel; Daniel E. Furst
View on Scopus
Discovery of (S)-1-(1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl)-4-(2-((1-methyl-1H-pyrazol-5-yl)amino)pyrimidin-4-yl)pyridin-2(1H)-one (GDC-0994), an Extracellular Signal-Regulated Kinase 1/2 (ERK1/2) Inhibitor in Early Clinical Development
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
James F. Blake; Michael Burkard; Jocelyn Chan; Huifen Chen; Kang-Jye Chou; Dolores Diaz; Danette Dudley; John J. Gaudino; Stephen Gould; Jonas Grina; Thomas Hunsaker; Lichuan Liu; Matthew Martinson; David Moreno; Lars Mueller; Christine Orr; Patricia Pacheco; Ann R. Qin; Kevin Rasor; Li Ren; Kirk D. Robarge; Sheerin Shahidi-Latham; Jeffrey Stults; Francis Sullivan; Weiru Wang; Jianping Yin; Aihe Zhou; Marcia Belvin; Mark Merchant; John Moffat; Jacob B. Schwarz
View on Scopus
Using Mass Spectrometry to Quantify Rituximab and Perform Individualized Immunoglobulin Phenotyping in ANCA-Associated Vasculitis
Analytical Chemistry, ISSN: 15206882 00032700
John R. Mills; Divi Cornec; Surendra Dasari; Paula M. Ladwig; Amber M. Hummel; Melissa Cheu; David L. Murray; Maria A. Willrich; Melissa R. Snyder; Hoffman; Cees Kallenberg; Langford; Peter A. Merkel; Paul A. Monach; Seo; Spiera; E. William St. Clair; John H. Stone; Specks; David R. Barnidge
View on Scopus
Expression profiling of constitutive mast cells reveals a unique identity within the immune system
Nature Immunology, ISSN: 15292916 15292908
Daniel F. Dwyer; Nora A. Barrett; K Frank Austen; Edy Y. Kim; Michael B. Brenner; Laura Shaw; Bingfei Yu; Ananda Goldrath; Sara Mostafavi; Aviv Regev; Andrew Rhoades; Devapregasan Moodley; Hideyuki Yoshida; Mathis; Christophe Benoist; Tsukasa Nabekura; Viola Lam; Lewis L. Lanier; Brian Brown; Miriam Merad; Viviana Cremasco; Shannon J. Turley; Monach; Michael L. Dustin; Yuesheng Li; Susan A. Shinton; Richard R. Hardy; Tal Shay; Yilin Qi; Katelyn Sylvia; Joonsoo Kang; Keke Fairfax; Gwendalyn J. Randolph; Michelle L. Robinette; Anja Fuchs; Marco Colonna
View on Scopus
Society for immunotherapy of cancer (SITC) statement on the proposed changes to the common rule
Journal for ImmunoTherapy of Cancer, ISSN: 20511426
Howard L. Kaufman; Lisa H. Butterfield; Pierre G. Coulie; Sandra Demaria; Robert L. Ferris; Jérôme Galon; Samir N. Khleif; Ira Mellman; Pamela S. Ohashi; Willem W. Overwijk; Suzanne L. Topalian; Francesco M. Marincola
View on Scopus
Regulatory T cell modulation by CBP/EP300 bromodomain inhibition
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Srimoyee Ghosh; Alexander M. Taylor; Melissa Chin; Hon-Ren Huang; Andrew R. Conery; Jennifer A. Mertz; Andres Salmeron; Pranal J. Dakle; Deanna Mele; Alexandre Côté; Hariharan Jayaram; Jeremy Setser; Florence Poy; Georgia Hatzivassiliou; Denise DeAlmeida-Nagata; Peter Sandy; Charlie Hatton; F. Anthony Romero; Eugene Y. Chiang; Thornik Reimer; Terry Crawford; Eneida Pardo; Venita G. Watson; Vickie Tsui; Andrea G Cochran; Laura E. Zawadzke; Jean-Christophe Harmange; James E. Audia; Barbara M. Bryant; Richard T Cummings; Steven Magnuson; Jane L. Grogan; Steve Bellon; Brian K Albrecht; Robert J. Sims; Jose M. Lora
View on Scopus
Phase I study of apitolisib (GDC-0980), dual phosphatidylinositol-3-kinase and mammalian target of rapamycin kinase inhibitor, in patients with advanced solid tumors
Clinical Cancer Research, ISSN: 15573265 10780432
Saoirse O. Dolly; Andrew Wagner; Bendell; Hedy L. Kindler; Lee M. Krug; Tanguy Y. Seiwert; Marjorie G. Zauderer; Martijn P. Lolkema; Doris Apt; Ru-Fang Yeh; Jill Fredrickson; Jill M. Spoerke; Koeppen; Joseph A. Ware; Jennifer O. Lauchle; Howard A. Burris; De Bono
View on Scopus
Outsourcing the immune response to cancer
Science, ISSN: 10959203 00368075
Mahesh Yadav; Lélia Delamarre
View on Scopus
Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Schmid; Sarah Pinder; Duncan Wheatley; Jane Macaskill; Charles Zammit; Jennifer Hu; Robert Price; Nigel Bundred; Sirwan Hadad; Alice Shia; Shah-Jalal Sarker; Louise Lim; Patrycja Gazinska; Natalie Woodman; Darren Korbie; Matt Trau; Paul Mainwaring; Steven Gendreau; Lackner; Mika K. Derynck; Wilson; Hannah Butler; Gemma Earl; Parker; Arnie Purushotham; Alastair Thompson
View on Scopus
Design and Development of a Series of Potent and Selective Type II Inhibitors of CDK8
ACS Medicinal Chemistry Letters, ISSN: 19485875
Philippe Bergeron; Michael F. T. Koehler; Elizabeth M. Blackwood; Krista K. Bowman; Clark; Ron Firestein; James R. Kiefer; Klaus Maskos; Mark L. McCleland; Linda O. Elliott; Sreemathy Ramaswamy; Laurent Salphati; Stephen Schmidt; Elisabeth V. Schneider; Jiansheng Wu; Beresini
View on Scopus
Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Terry Crawford; Vickie Tsui; E. Megan Flynn; Shumei Wang; Alexander M. Taylor; Alexandre Côté; James E. Audia; Beresini; Burdick; Richard T Cummings; Leslie A. Dakin; Martin Duplessis; Andrew C. Good; Michael C. Hewitt; Hon-Ren Huang; Hariharan Jayaram; James R. Kiefer; Ying Jiang; Jeremy Murray; Christopher G. Nasveschuk; Eneida Pardo; Florence Poy; F. Anthony Romero; Yong Tang; Jian Wang; Zhaowu Xu; Laura E. Zawadzke; Xiaoyu Zhu; Brian K Albrecht; Steven Magnuson; Steve Bellon; Andrea G Cochran
View on Scopus
Chemically Diverse Group i p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Joachim Rudolph; Lesley J. Murray; Chudi O. Ndubaku; Thomas O'Brien; Elizabeth M. Blackwood; Weiru Wang; Ignacio Aliagas; Lewis Gazzard; James J. Crawford; Joy Drobnick; Wendy Lee; Xianrui Zhao; Klaus P. Hoeflich; David A. Favor; Ping Dong; Haiming Zhang; Christopher E. Heise; Angela Oh; Christy C. Ong; Hank La; Paroma Chakravarty; Connie Chan; Diana Jakubiak; Jennifer A. Epler; Sreemathy Ramaswamy; Roxanne Vega; Cain; Dolores Diaz; Yu Zhong
View on Scopus
The Structural Basis for Class II Cytokine Receptor Recognition by JAK1
Structure, ISSN: 18784186 09692126
Ryan Ferrao; Heidi J. A. Wallweber; Hoangdung Ho; Christine Tam; Yvonne Franke; John Quinn; Patrick J. Lupardus
View on Scopus
Isolation and Characterization of Monoclonal Antibody Charge Variants by Free Flow Isoelectric Focusing
Analytical Chemistry, ISSN: 15206882 00032700
Brian Hosken; Charlene Li; Berny Mullappally; Carl Co; Boyan Zhang
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.